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Biochemical Responses in Freshwater Fish Exposed to Insecticide Propoxur

Abstract

Although designed to control pests selectively, there is some evidence that environmental contamination by pesticides increases risks for humans and wildlife. In the present study, we evaluated biomarkers of oxidative stress in Astyanax jacuhiensis exposed to (5, 15 and 30 µg L−1) of carbamate Propoxur (PPX) for 96 h. Glutathione S-transferase (GST) in liver and gills showed reduced activity in all PPX concentrations tested. Acetylcholinesterase (AChE) activities reduced in brain and muscle at concentrations 15 and 30 µg L−1 of PPX. Lipid peroxidation (LPO) and hydrogen peroxide (HP) had no significant differences. In the brain, protein carbonyl (PC) increased in all groups treated with PPX. Although PPX is a selective pesticide, it causes oxidative damage and enzyme alteration in fish. This study pointed out some biomarkers that could be used to assess effects of environmentally relevant concentrations of pesticides, and infer about studies using fish as bioindicator.

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Acknowledgements

We would like to thank Universidade Federal de Santa Maria (UFSM) for the support and the financial support and fellowships from the Brazilian agencies CAPES (Coordination for the Improvement of Higher Education Personnel) and CNPq (National Council for Scientific and Technological Development) for research´s fellowship to Vania Lucia Loro.

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Correspondence to Vania Lucia Loro.

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Gonçalves, C.R., Marins, A.T., do Amaral, A.M.B. et al. Biochemical Responses in Freshwater Fish Exposed to Insecticide Propoxur. Bull Environ Contam Toxicol 100, 524–528 (2018). https://doi.org/10.1007/s00128-018-2285-9

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Keywords

  • Characidae
  • Toxicology
  • Oxidants
  • Carbamate