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Potentiation Effect of Metolachlor on Toxicity of Organochlorine and Organophosphate Insecticides in Earthworm Eisenia andrei

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Abstract

Acetylcholinesterase, glutathione-S-transferase and catalase activities were determined in earthworms Eisenia andrei exposed to insecticides (endosulfan, temephos, malathion, pirimiphos-methyl) alone and in a binary combination with the herbicide metolachlor. Metolachlor individually was not acutely toxic, even at high concentrations applied; however, in the treated earthworms metolachlor enhanced the toxicity of endosulfan and temephos by significantly reducing the acetylcholinesterase activity. In binary combination with malathion and pirimiphos-methyl, metolachlor did not increase toxicity. The potentiation character of metolachlor is specific rather than general, and probably depends on the chemical structure of pesticides in the mixture.

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Correspondence to Branimir K. Hackenberger.

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Stepić, S., Hackenberger, B.K., Velki, M. et al. Potentiation Effect of Metolachlor on Toxicity of Organochlorine and Organophosphate Insecticides in Earthworm Eisenia andrei . Bull Environ Contam Toxicol 91, 55–61 (2013). https://doi.org/10.1007/s00128-013-1000-0

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  • DOI: https://doi.org/10.1007/s00128-013-1000-0

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