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Assessment of the Levels of Polybrominated Diphenyl Ethers in Blood Samples from Guadalajara, Jalisco, Mexico


The purpose of this study was to measure levels of polybrominated diphenyl ethers (PBDEs) in the blood of children (50 individuals) living in Guadalajara, Jalisco, Mexico. We analyzed six PBDE congeners by gas chromatography–mass spectrometry. Total PBDE levels ranged from not detectable (nd) to 15.2 μg/L on a whole-weight basis and from nd to 6,435 ng/g lipid on a lipid-weight basis. The dominant congener in our study was BDE-153, followed by BDE-154, BDE-99, BDE-100, and BDE-47. Levels of BDE-209 were below the detection limit. Our data indicate that children living in the areas studied in this work are exposed to high levels of PBDEs.

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  1. Athanasiasou M, Cuadra SN, Marsh G, Bergman A, Jakobson K (2008) Polybrominated diphenyl ethers (PBDEs) and bioaccumulative hydroxylated PBDE metabolites in young humans from Managua, Nicaragua. Environ Health Perspect 116:400–408

    Article  Google Scholar 

  2. Bergonzi R, De Palma G, Tomasi C, Cristina Ricossa M, Apostoli P (2009) Evaluation of different methods to determine total serum lipids for normalization of circulating organochlorine compounds. Int Arch Occup Environ Health 82:1241–1247

    Article  CAS  Google Scholar 

  3. Carrizo D, Grimalt JO (2007) Influence of breastfeeding in the accumulation of polybromodiphenyl ethers during the first years of child growth. Environ Sci Technol 41:4907–4912

    Article  CAS  Google Scholar 

  4. Costa LG, Giordano G, Tagliaferri S, Caglieri A, Mutti A (2008) Polybrominated diphenyl ether (PBDE) flame retardants: environmental contamination, human body burden and potential adverse health effects. Acta Biomed 79:172–183

    CAS  Google Scholar 

  5. Fängström B, Hovander L, Bignert A, Athanassiadis I, Linderholm L, Grandjean P, Weihe P, Bergman A (2005a) Concentrations of polybrominated diphenyl ethers, polychlorinated biphenyls, and polychlorobiphenylols in serum from pregnant Faroese women and their children 7 years later. Environ Sci Technol 39:9457–9463

    Article  Google Scholar 

  6. Fängström B, Strid A, Grandjean P, Weihe P, Bergman A (2005b) A retrospective study of PBDEs and PCBs in human milk from the Faroe Islands. Environ Health 4:12

    Article  Google Scholar 

  7. Han GG, Ding GQ, Lou XM, Wang XF, Han JL, Shen HT, Zhou Y, Du LY (2011) Correlations of PCBs, DIOXIN, and PBDE with TSH in children’s blood in areas of computer e-waste recycling. Biomed Environ Sci 24:112–116

    CAS  Google Scholar 

  8. Link B, Gabrio T, Mann V, Schilling B, Maisner V, König M, Flicker-Klein A, Zöllner I, Fischer G (2012) Polybrominated diphenyl ethers (PBDE) in blood of children in Baden Württemberg between 2002/03 and 2008/09. Int J Hyg Environ Health 215:224–228

    Article  CAS  Google Scholar 

  9. Lopez D, Athanasiadou D, Athanassiadis I, Yañez L, Ramirez R, Díaz-Barriga F, Bergman A (2006) Estudio preliminar sobre los niveles de exposición a PBDEs en sangre y leche materna en México. Acta Toxicol Argent 14:52–54

    Google Scholar 

  10. NHANES IV (2009) Third National Report on Human Exposure to Environmental Chemicals. Department of Health and Human Services Centers for Disease Control and Prevention, Atlanta

  11. Pérez-Maldonado IN, Ramírez-Jiménez Mdel R, Martínez-Arévalo LP, López-Guzmán OD, Athanasiadou M, Bergman A, Yarto-Ramírez M, Gavilán-García A, Yáñez L, Díaz-Barriga F (2009) Exposure assessment of polybrominated diphenyl ethers (PBDEs) in Mexican children. Chemosphere 75:1215–1220

    Article  Google Scholar 

  12. Rose M, Bennett DH, Bergman A, Fängström B, Pessah IN, Hertz-Picciotto I (2010) PBDEs in 2–5 year-old children from California and associations with diet and indoor environment. Environ Sci Technol 44:2648–2653

    Article  CAS  Google Scholar 

  13. Tan J, Cheng SM, Loganath A, Chong YS, Obbard JP (2007) Polybrominated diphenyl ethers in house dust in Singapore. Chemosphere 66:985–992

    Article  CAS  Google Scholar 

  14. Toms LL, Sjödin A, Harden F, Hobson P, Jones R, Edenfield E, Mueller JF (2009) Serum polybrominated diphenyl ether (PBDE) levels are higher in children (2–5 years of age) than in infants and adults. Environ Health Perspect 117:1461–1465

    Article  CAS  Google Scholar 

  15. Trejo-Acevedo A, Díaz-Barriga F, Carrizales L, Domínguez G, Costilla R, Ize-Lema I, Yarto-Ramírez M, Gavilán-García A, Mejía-Saavedra J, Pérez-Maldonado IN (2009) Exposure assessment of persistent organic pollutants and metals in Mexican children. Chemosphere 74:974–980

    Article  CAS  Google Scholar 

  16. United Nations Environment Program (2012) Report of the conference of the parties to the Stockholm convention on persistent organic pollutants on the work of its fifth meeting. Accessed 04 February 2012

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This work was supported by a grant from the Consejo Nacional de Ciencia y Tecnología, Mexico, CONACYT-SEMARNAT 107900.

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Correspondence to Iván N. Pérez-Maldonado.

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Orta-Garcia, S.T., León-Moreno, L.C., González-Vega, C. et al. Assessment of the Levels of Polybrominated Diphenyl Ethers in Blood Samples from Guadalajara, Jalisco, Mexico. Bull Environ Contam Toxicol 89, 925–929 (2012).

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  • Brominated flame retardants
  • Children
  • Mexico
  • BDE47
  • PBDEs
  • POPs