Toxicological Responses of Cyprinus carpio Exposed to a Commercial Formulation Containing Glyphosate

  • Roberta Cattaneo
  • Bárbara Clasen
  • Vania Lucia Loro
  • Charlene Cavalheiro de Menezes
  • Alexandra Pretto
  • Bernardo Baldisserotto
  • Adriana Santi
  • Luis Antonio de Avila
Article

DOI: 10.1007/s00128-011-0396-7

Cite this article as:
Cattaneo, R., Clasen, B., Loro, V.L. et al. Bull Environ Contam Toxicol (2011) 87: 597. doi:10.1007/s00128-011-0396-7

Abstract

The effects of commercial glyphosate herbicide formulation on the activity of acetylcholinesterase (AChE) enzyme and oxidative stress were studied in Cyprinus carpio exposed for 96 h to 0.0, 0.5, 2.5, 5.0 and 10.0 mg/L and then allowed to equal recovery period in water without herbicide. The activity of AChE was inhibited in the brain and in the muscle after exposure. However, after recovery period brain and muscle AChE activity increased. Brain thiobarbituric acid reactive species (TBARS) were measured as an indicator of oxidative stress. Increased TBARS levels were observed with all concentrations tested of the glyphosate formulation, and remained increased after the recovery period. The results recorded clearly indicate lipid peroxidation and anti-AChE action induced by Roundup® exposure.

Keywords

Glyphosate Carp AChE TBARS 

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Roberta Cattaneo
    • 3
  • Bárbara Clasen
    • 3
  • Vania Lucia Loro
    • 1
  • Charlene Cavalheiro de Menezes
    • 3
  • Alexandra Pretto
    • 3
  • Bernardo Baldisserotto
    • 2
  • Adriana Santi
    • 3
  • Luis Antonio de Avila
    • 4
  1. 1.Departamento de QuímicaCentro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria (UFSM)Santa MariaBrazil
  2. 2.Departamento de FisiologiaCentro de Ciências da Saúde, Universidade Federal de Santa Maria (UFSM)Santa MariaBrazil
  3. 3.Programa de Pós-graduação em Bioquímica ToxicológicaUFSMSanta MariaBrazil
  4. 4.Departamento de FitossanidadeUniversidade Federal de Pelotas (UFPel)PelotasBrazil

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