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Antioxidant Responses and Bioaccumulation in Green-lipped Mussels (Perna Viridis) Under Acute Tributyltin Chloride Exposure

Abstract

Green-lipped mussels (Perna viridis) were exposed to waterborne tributyltin chloride (TBTCl) at different concentrations (0.2, 0.4 and 0.8 μg L−1) for up to 72 h. Accumulated TBTCl in Perna viridis correlated linearly with the exposure concentrations of 0.2 μg L−1(R2 = 0.772), 0.4 μg L−1(R2 = 0.952), and 0.8 μg L−1(R2 = 0.909). The results of superoxide dismutase (SOD), glutathione peroxidase (GPx) and malondialdehyde (MDA) all decreased in gill tissues after 24 h of exposure, but the hepatic SOD and the hepatic GPx showed either little or no effect on exposure of TBTCl solutions. Analysis using the Spearman rank correlation coefficient showed the hepatic GPx activity appeared to have a significant negative correlativity (Rs = −0.42) with the exposed TBTCl concentrations, and the hepatic MDA was significantly negatively correlated (Rs = −0.33) with the tissue TBTCl concentrations. Conversely, a significant positive correlation (Rs = 0.60) was shown between the gill MDA contents and exposure time. This study illustrates oxyradical scavenger GPx best correlated with stress level of pollutants among the various antioxidant parameters.

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Acknowledgments

This work was supported by grants from the Research Project of Public Welfare, Ministry of Science and Technology of China (No. 2005DIB3J021), the Science and technology projects of Guangdong Province, China (No. 2009B030600001) and Central Public-interest Scientific Institution Basal Research Fund of China (No. 2009YD01).

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Correspondence to Xiao-Ping Jia.

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Chen, HG., Jia, XP., Cai, WG. et al. Antioxidant Responses and Bioaccumulation in Green-lipped Mussels (Perna Viridis) Under Acute Tributyltin Chloride Exposure. Bull Environ Contam Toxicol 87, 506 (2011). https://doi.org/10.1007/s00128-011-0390-0

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Keywords

  • Antioxidant response
  • Bioaccumulation
  • Tributyltin chloride (TBTCl)
  • Marine mussels (Perna viridis)