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Seventeen-Year Observation on Urinary Cadmium and β2-Microglobulin in Inhabitants After Cessation of Cadmium-Exposure in Japan

Abstract

The purpose of this study was to clarify the change and relationship of urinary cadmium (Cd) and β2-microglobulin (β2-MG) concentrations of inhabitants in Cd-polluted areas after soil restoration. The urinary Cd and β2-MG concentrations of 25 males and 28 females did not show a significant change, 22 years after the Cd-polluted soil was restored. Once exposed to Cd, it was found to remain in the body, 22 years after the Cd -polluted soil was restored. However, this did not influence renal tubular dysfunction in most of the younger generation compared with elders heavily exposed to Cd.

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Acknowledgments

The authors thank the inhabitants of the Kanehira area, who had to endure physical examinations over a period of 17 years. Also, we sincerely wish the inhabitants of the Kanehira area good health and long lives.

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Correspondence to Reiko Sato.

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Sato, R., Kido, T., Honda, R. et al. Seventeen-Year Observation on Urinary Cadmium and β2-Microglobulin in Inhabitants After Cessation of Cadmium-Exposure in Japan. Bull Environ Contam Toxicol 84, 363–367 (2010). https://doi.org/10.1007/s00128-010-9947-6

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Keywords

  • Urinary-Cadmium
  • Urinary-β2-Microglobulin
  • Biological half life
  • Soil restoration