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Toxicity of Waterborne Copper in Premetamorphic Tadpoles of Lithobates catesbeianus (Shaw, 1802)

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Abstract

Toxicity parameters of Copper to pre-metamorphic larvae of Lithobates catesbeianus were evaluated in laboratory conditions. The acute toxicity (as LC-50 96 h) was 3.96 mg Cu2+ L−1 (95% confidence interval: 3.21–4.89); the bioconcentration of the metal after 96 h exposure followed an exponential increase. The potential genotoxicity effect evaluated with Micronucleus Test showed a reduced sensitivity of the animals to the assayed concentrations of the metal, exhibiting only a modest increase in the frequency of erythrocytes micronuclei, meanwhile larvae exposed to cyclophosphamide (positive control) showed significant increases. The Condition Factor was significantly reduced while the Hepatosomatic Index remained unaltered.

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Acknowledgments

Supported in part by grants from the CIC-Buenos Aires, ANPCyT and UNLu.

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Correspondence to Alfredo Salibián.

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Ossana, N.A., Castañé, P.M., Poletta, G.L. et al. Toxicity of Waterborne Copper in Premetamorphic Tadpoles of Lithobates catesbeianus (Shaw, 1802). Bull Environ Contam Toxicol 84, 712–715 (2010). https://doi.org/10.1007/s00128-010-0014-0

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  • DOI: https://doi.org/10.1007/s00128-010-0014-0

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