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A Body-Weight-Based Method to Estimate Inorganic Arsenic Body Burden Through Tilapia Consumption in Taiwan

Abstract

In the present study, a stage-classified exposure model is developed to better characterize long-term arsenic (As) accumulation of both genders of children, adolescents, and adults through tilapia consumption in Taiwan. Ingestion rate as well as elimination rate of As are treated dynamically and are used to parameterize the stage-classified accumulation model. Model simulations are carried out to produce temporal changes of As body burden of the residents who consume tilapia from blackfoot disease (BFD)-endemic area in three major cities in Taiwan. The model presented here can be served as a strong framework for refining human health risk assessments through fish consumption.

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References

  1. Caussy D (2003) Case studies of the impact of understanding bioavailability: arsenic. Ecotoxicol Environ Saf 56:164–173

    Article  CAS  Google Scholar 

  2. Chen CJ, Hsueh YM, Tseng MP, Lin YC, Hsu LI, Chou WL, Chiou HY, Wang IH, Chou YL, Tseng CH, Liou SH (2001) Individual susceptibility to arseniasis. In: Chappell WR, Abernathy CO, Calderon RL (eds) Arsenic exposure and health effects IV. Elsevier, Oxford, UK, pp 135–143

    Google Scholar 

  3. Gross-Sorokin MY, Grist EPM, Cooke M, Crane M (2003) Uptake and depuration of 4-nonylphenol by the benthic invertebrate Gammarus pulex: how important is feeding rate? Environ Sci Technol 37:2236–2241

    Article  CAS  Google Scholar 

  4. Huang YK, Lin KH, Chen HW, Chang CC, Liu CW, Yang MH, Hsueh YM (2003) Arsenic species contents at aquaculture farm and in farmed mouthbreeder (Oreochromis mossambicus) in blackfoot disease hyperendemic areas. Food Chem Toxicol 41:1491–1500

    Article  CAS  Google Scholar 

  5. Liao CM, Chen BC, Singh S, Lin MC, Liu CW, Han BC (2003) Acute toxicity and bioaccumulation of arsenic in tilapia (Oreochromis mossambicus) from a blackfoot disease area in Taiwan. Environ Toxicol 18:252–259

    Article  CAS  Google Scholar 

  6. Liao CM, Chen BC, Tsai JW, Chen JW, Ling MP, Chou YH (2004) A parsimonious AUC-based biokinetic method to estimate relative bioavailable zinc to abalone Haliotis diversicolor supertexta. Aquaculture 232:425–440

    Article  CAS  Google Scholar 

  7. Lin MC, Lin HY, Cheng HH, Chen YC, Liao CM, Shao KT (2005) Risk assessment of arsenic exposure from consumption of cultured milkfish, Chanos chanos (Forsskal), from the arsenic-contaminated area in southwestern Taiwan. Bull Environ Contam Toxicol 75:637–644

    Article  CAS  Google Scholar 

  8. Ling MP, Liao CM, Tsai JW, Chen BC (2005) A PBTK/TD Modeling-based approach can assess arsenic bioaccumulation in farmed tilapia (Oreochromis mossambicus) and human health risks. Integr Environ Assess Manag 1:40–54

    Article  CAS  Google Scholar 

  9. Llobet JM, Falco G, Casas C, Teixido A, Domingo JL (2003) Concentrations of arsenic, cadmium, mercury, and lead in common foods and estimated daily intake by children, adolescents, adults, and seniors of Catalonia, Spain. J Agric Food Chem 51:838–842

    Article  CAS  Google Scholar 

  10. Lung SCC, Chen CF, Hu SC, Bau YP (2003) Exposure of Taiwan residents to polychlorinated biphenyl congeners from farmed, ocean-caught, and imported fish. Environ Sci Technol 37:4579–4585

    Google Scholar 

  11. Mann S, Droz PO, Vahter M (1996) A physiologically based pharmacokinetic model for arsenic exposure. II. Validation and application in humans. Toxicol Appl Pharmacol 140:471–486

    Article  CAS  Google Scholar 

  12. Muñoz O, Devesa V, Suñer MA, Vélez D, Montoro R, Urieta I, Macho ML, Jalón M (2000) Total and inorganic arsenic in fresh and processed fish products. J Agric Food Chem 48:4369–4376

    Article  Google Scholar 

  13. Pomroy C, Charbonneau SM, McCullough RS, Tam GKH (1980) Human retention studies with arsenic. Toxicol Appl Pharmacol 53:550–556

    Article  CAS  Google Scholar 

  14. Reinfelder JR, Fisher NS, Luoma SN, Nichols JW, Wang WX (1998) Trace element trophic transfer in aquatic organisms: a critique of the kinetic model approach. Sci Total Environ 219:117–135

    Article  CAS  Google Scholar 

  15. Schoof RA, Yost LJ, Eickhoff J, Crecelius EA, Cragin DW, Meacher DM, Menzel DB (1999) A market basket survey of inorganic arsenic in food. Food Chem Toxicol 37:839–846

    Article  CAS  Google Scholar 

  16. Tsuji JS, Benson R, Schoof RA, Hook GC (2004) Health effect levels for risk assessment of childhood exposure to arsenic. Regul Toxicol Pharmacol 39:99–110

    Article  CAS  Google Scholar 

  17. Vahter M (2002) Mechanisms of arsenic biotransformation. Toxicol 181–182:211–217

    Article  Google Scholar 

  18. Yost LJ, Tao SH, Egan SK, Barraj LM, Smith KM, Tsuji JS, Lowney YW, Schoof RA, Rachman NJ (2004) Estimation of dietary intake of inorganic arsenic in U.S. children. Hum Ecol Risk Assess 10:473–483

    Article  CAS  Google Scholar 

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Acknowledgments

This study was supported by the National Science Council of Republic of China under Grant NSC 95-2313-B-451-001.

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Correspondence to B.-C. Chen.

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Chen, BC., Liao, CM. A Body-Weight-Based Method to Estimate Inorganic Arsenic Body Burden Through Tilapia Consumption in Taiwan. Bull Environ Contam Toxicol 80, 289–293 (2008). https://doi.org/10.1007/s00128-008-9365-1

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Keywords

  • Arsenic
  • Tilapia
  • Body weight
  • Human health risk assessment