This study reports significant alterations in various haematological parameters such as red and white blood corpuscles counts, haemoglobin content and packed cell volume in adult Swiss albino mice orally administered with diluted distillery soil leachate (5%–20%) for 30 days. Soil leachate also affected red blood cell morphology (poikilocytosis). The haematology of exposed mice improved in the reversal groups. Present study infers contamination potential of distillery soil leachate in the groundwater.
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Banerjee AC, Bajwa I, Bathal KK (2004) Effect of distillery effluents on grown of Casuarina equselfoliaI. Pollut Res 23(1):179–182
Bhaduri TJ (1980) Treatments alterations for spent wash from distilleries. An overview. In: Tyagi PC, Tripathi A (eds) Proc of seminar on disposal of sugar mill and distillery effluents, vol II, pp 34–46
Blair PC, Thompson MB, Bechtold M, Wilson RE, Moorman MP, Fowler BA (1990) Evidence for oxidative damage to red blood cells in mice induced by arsine gas. Toxicol 63:25–34
Bukowska B, Kowalska S (2003) The presence and toxicity of phenol derivatives—their effect on human erythrocytes. Curr Top Biophys 27(1–2):43–51
Central Pollution Control Board (CPCB) (1989) Status of water supply and wastewater collection treatment and disposal in class I cities—report of Central Pollution Control Board
Chandravathy VM, Sreedevi V, Reddy SLN (1996) Haematological alterations induced by lead nitrate in adult male Swiss albino mice. J Environ Pollut 3(3,4):207–209
Dacie JV, Lewis SM (1977) Practical haematology, 15th edn. ELBS, Churchill, Livingstone
Devarajan L, G Oblisami (1995) Effects of distillery effluents on plant and soil enzymatic activities and groundnut quality. Madras Agric J 82:664
Dubey RC (1993) A textbook of biotechnology. Chand S & Company Ltd, New Delhi:139–241
Duchnowicz P, Koter M, Duda W (2002) Damage of erythrocyte by phenoxy-acetic herbicides and their metabolites. Pestic Biochem Physiol 74:1–7
Eaton DL, Klaassen CD (1998) Principals of toxicology. In: Klaassen CD (Ed) Toxicology. The basic science of poison, 5th edn, pp 335–354
Fischbach F (1984) A manuel of laboratory diagnostic tests. JB Lippincott Company, New York, pp 1–898
Ghai CL (1993) A text book of practical physiology, 4th edn. Jaypee, pp 1–367
Guilthermino L, Soares AMVM, Carvalho AP, Lopes MC (1998) Effect of cadmium and parathion exposure on hematology and blood biochemistry of adult male rats. Bull Environ Contam Toxicol 60:52–59
Khanna DR, Bhutiani R, Kumar P (2003) Characterization of a treated distillery effluent. Nat Environ Pollut Tech 2(1):113–114
Kou HW, Jain GJ, Chen CL, Liu CS, Lai JS (1997) White blood cell count as an indicator of formaldehyde exposure. Bull Environ Contam Toxicol 59:261–267
Kumar S, Gopal K (2001) Impact of distillery effluent on physiological consequences in the fresh water teleost Channa punctatus. Bull Environ Contam Toxicol 66:617–622
Larsson A, Haux C, Sjobeck M (1985) Fish physiology and metal pollution results and experiences from laboratory and field studies. Ecotoxicol Environ 9:250–281
Lopez LE, Favari L, Martinez TL, Madrigal M, Soto C (2003) Hazard assessment of a mixture of pollutants from a sugar industry to three fish species of western Mexico by the responces of enzymes and lipid peroxidation. Bull Environ Contam Toxicol 70:739–745
Lynch MJ, Rakhael SS, Miller LD, Space DD, Inwood MJH (1969) Medical laboratory technology and clinical pathology, 2nd edn. WB Saunders Co, Phaladelphia, pp 1–299
Mathur N, Krishnatrey R, Sharma S, Pathak S, Sharma KP (2003) Certain haematological responses in Swiss albino mice following exposure to textile dye wastewater. J Environ Biol 24(2):161–164
Nunes AC, Mathias MDL, Crespo AM (2001) Morphological and haematological parameters in the Algerian mouse (Mus spretus) inhabiting an area contaminated with heavy metals. Environ Pollut 113:87–93
Oda H, Haux H, Nakajima H (1980) Reduction of haemoglobin with nitric oxide and nitrogen dioxide in mice. J Toxicol Environ 6:673–678
Pathade GR (1999) A review of current technologies for distillery wastewater treatment. Technoscience, Jaipur
Reddy GH, Chetty CS, Reddy GR (2003) Alterations in haematological parameters of lead exposed and α-tocopherol administered developing rats. Indian J Comp Animal Physiol 21:71–76
Sateesh TVR, Nayak V, Anjaneyulu GVSR, Mishra KD (1999) Fytolan induced alterations in the blood of male Swiss albino mice. Indian J Environ Sci 3(1):75–79
Shaw BP, Dash S, Panigrahi AK (1991) Effect of methyl mercuric chloride treatment on haematological characteristics and erythrocyte morphology of Swiss mice. Environ Pollut 73:43–52
Varma MC, Pratap R (2006) Effect of distillery effluent on certain biochemical and hematological characteristics of swiss albino mice, Mus musculus. J Haematol Ecotoxicol 1(1):13–20
Authors wish to express their sincere thanks to the Head, Department of Zoology, University of Rajasthan, Jaipur, to provide technical support, DBT, New Delhi, for financial support and CSIR, New Delhi for awarding Research Associateship to Dr. Shweta Sharma.
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Sharma, S., Sharma, A., Singh, P.K. et al. Impact of Distillery Soil Leachate on Haematology of Swiss Albino Mice (Mus musculus). Bull Environ Contam Toxicol 79, 273–277 (2007). https://doi.org/10.1007/s00128-007-9225-4
- Distillery soil leachate
- Swiss albino mice