Abstract
Purpose
Ethnic minority groups with early psychosis may have longer treatment delays, potentially leading to poorer outcomes. We updated a previous systematic review of the literature on racial and ethnic differences in duration of untreated psychosis (DUP) among people with first-episode psychosis.
Results
Six of 17 studies described significant differences across aggregated racial groups; however, the pooled estimates did not show differences across groups. Additional data from this update allowed for disaggregated analyses, finding that Black-African groups have a shorter DUP, whereas Black-Caribbean groups have longer DUP, relative to White groups.
Conclusions
These findings highlight the importance of in-depth research on disaggregated ethnic groups to inform targeted early intervention strategies for minority populations.
References
Perkins DO, Gu H, Boteva K, Lieberman JA (2005) Relationship between duration of untreated psychosis and outcome in first-episode schizophrenia: a critical review and meta-analysis. Am J Psychiatry 162:1785–1804
Marshall M, Lewis S, Lockwood A, Drake R, Jones P, Croudace T (2005) Association between duration of untreated psychosis and outcome in cohort of first-episode patients: a systematic review. Arch Gen Psychiatry 62:975–983
Norman RMG, Malla AK, Verdi MB, Hassall LD, Fazekas C (2004) Understanding delay in treatment for first-episode psychosis. Psychol Med 34:255–266
Mcgorry PD, Killackey E, Yung AR (2007) Early intervention in psychotic disorders: detection and treatment of the first episode and the critical early stages 187:S8–S10
Anderson KK, Flora N, Archie S, Morgan C, Mckenzie K (2014) A meta-analysis of ethnic differences in pathways to care at the first episode of psychosis. Acta Psychiatr Scand 130:257–268
Anderson KK, Flora N, Archie S, Morgan C, McKenzie K (2014) Race, ethnicity, and the duration of untreated psychosis: a systematic review. Soc Psychiatry Psychiatr Epidemiol 49:1161–1174
The World Bank Group (2019) High income. [Online]. Available: https://data.worldbank.org/income-level/high-income
Bhui K, Stansfeld S, Hull S, Priebe S, Mole F, Feder G (2003) Ethnic variations in pathways to and use of specialist mental health services in the UK: systematic review. Br J Psychiatry 182:105–116
Sass B, Moffat J, Bhui K, Mckenzie K (2009) Enhancing pathways to care for black and minority ethnic populations: a systematic review. Int Rev Psychiatry 21:430–438
Morgan C, Fearon P, Hutchinson G, McKenzie K, Lappin JM, Abdul-Al R et al (2006) Duration of untreated psychosis and ethnicity in the AESOP first-onset psychosis study. Psychol Med 36:239–247
Ghali S, Fisher HL, Joyce J, Major B, Hobbs L, Soni S et al (2013) Ethnic variations in pathways into early intervention services for psychosis. Br J Psychiatry 202:277–283
de Dominguez MG, Fisher HL, Major B, Chisholm B, Rahaman N, Joyce J et al (2013) Duration of untreated psychosis in adolescents: ethnic differences and clinical profiles. Schizophr Res 150:526–532
Haas GL, Garratt LS, Sweeney JA (1998) Delay to first antipsychotic medication in schizophrenia: impact on symptomatology and clinical course of illness. J Psychiatr Res 32:151–159
Basu S, Subramaniam M, Abdin E, Poon LY, Verma S (2015) Does ethnicity have an impact on duration of untreated psychoses: a retrospective study in Singapore. Int J Soc Psychiatry 61:623–630
Van Der Ven E, Bourque F, Joober R, Selten J-P, Malla A (2012) Comparing the clinical presentation of first-episode psychosis across different migrant and ethnic minority groups in Montreal, Quebec. Can J Psychiatry 57:300–308
Singh SP, Brown L, Winsper C, Gajwani R, Islam Z, Jasani R et al (2015) Ethnicity and pathways to care during first episode psychosis: the role of cultural illness attributions. BMC Psychiatry 15:1–8
Pek E, Mythily S, Chong S (2006) Clinical and social correlates of duration of untreated psychosis in first-episode psychosis patients. Ann Acad Med Singap 35:24–26
Archie S, Akhtar-Danesh N, Norman R, Malla A, Roy P, Zipursky RB (2010) Ethnic diversity and pathways to care for a first episode of psychosis in Ontario. Schizophr Bull 36:688–701
Drake RJ, Haley CJ, Akhtar S, Lewis SW (2000) Causes and consequences of duration of untreated psychosis in schizophrenia. Br J Psychiatry 177:511–515
Turner M, Smith-Hamel C, Mulder R (2006) Pathways to care in a New Zealand first-episode of psychosis cohort. Aust N Z J Psychiatry 40:421–428
Compton MT, Chien VH, Leiner AS, Goulding SM, Weiss PS (2008) Mode of onset of psychosis and family involvement in help-seeking as determinants of duration of untreated psychosis. Soc Psychiatry Psychiatr Epidemiol 43:975–982
Brunet K, Birchwood M, Lester H, Thornhill K (2007) Provision of child and adolescent mental health in-patient services in Englad between 1999 and 2006. Psychiatr Bull 31:408–410
Addington J, Heinssen RK, Robinson DG, Schooler NR, Marcy P, Brunette MF et al (2015) Duration of untreated psychosis in community treatment settings in the United States. Psychiatr Serv 66:753–756
Reichert A, Jacobs R (2018) Socioeconomic inequalities in duration of untreated psychosis: evidence from administrative data in England. Psychol Med 48:822–833
Anderson KK, Flora N, Ferrari M, Tuck A, Archie S, Kidd S et al (2015) Pathways to first-episode care for psychosis in African-, Caribbean-, and European-origin groups in Ontario. Can J Psychiatry 60:223–231
Harrison G, Holton A, Neilson D, Owens D (1989) Severe mental disorder in Afro-Caribbean patients: some social, demographic and service factors. Psychol Med 19:683–696
Morgan C, Fearon P, Lappin J, Heslin M, Donoghue K, Lomas B et al (2017) Ethnicity and long-term course and outcome of psychotic disorders in a UK sample: the AEsOP-10 study. Br J Psychiatry 211:88–94
Ferrari M, Flora N, Anderson KK, Tuck A, Archie S, Kidd S et al (2015) The African, Caribbean and European (ACE) pathways to care study: a qualitative exploration of similarities and differences between African-origin, Caribbean-origin and European-origin groups in pathways to care for psychosis. BMJ Open 5:1–12
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ESM_1: Flow chart of the search strategy and exclusion process for the systematic review (PDF 15 kb)
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ESM_3: Findings on duration of untreated psychosis and ethnic/racial group for studies included in the systematic review (n = 17) (XLSX 17 kb)
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ESM_5: Meta-analysis of the log-transformed standardized mean difference (SMD) in duration of untreated psychosis for Black and Asian groups relative to White (PNG 50 kb)
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Schoer, N., Huang, C.W. & Anderson, K.K. Differences in duration of untreated psychosis for racial and ethnic minority groups with first-episode psychosis: an updated systematic review and meta-analysis. Soc Psychiatry Psychiatr Epidemiol 54, 1295–1298 (2019). https://doi.org/10.1007/s00127-019-01737-3
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DOI: https://doi.org/10.1007/s00127-019-01737-3