Lifetime prevalence and age-of-onset of mental disorders in adults from the Argentinean Study of Mental Health Epidemiology

  • Alfredo H. Cía
  • Juan Carlos Stagnaro
  • Sergio Aguilar Gaxiola
  • Horacio Vommaro
  • Gustavo Loera
  • María Elena Medina-Mora
  • Sebastían Sustas
  • Corina Benjet
  • Ronald C. Kessler
Original Paper

Abstract

Purpose

Although the Global Burden of Disease Study estimated that depressive disorders and anxiety disorders are the second and fifth leading causes of disability in Argentina, these estimates were based on imputations rather than epidemiological data. The policy implications of these results for the necessary expansion of mental health services in Argentina are sufficiently great that more direct estimates of the population burdens of common mental disorders are needed. Therefore, the purpose is to present the first results regarding lifetime prevalence, projected lifetime risk up to age 75, age-of-onset, cohort effects and socio-demographic correlates of DSM-IV mental disorders among adults (18+) from the general population of urban areas of Argentina.

Method

A multistage clustered area probability household survey was administered to 3927 individuals using the World Mental Health Composite International Diagnostic Interview.

Results

Lifetime prevalence of any disorder was 29.1% and projected lifetime risk at age 75 was 37.1%. Median age-of-onset of any disorder was 20 years of age. Disorders with highest lifetime prevalence were major depressive disorder (8.7%), alcohol abuse (8.1%), and specific phobia (6.8%). Anxiety disorders were the most prevalent group of disorder (16.4%) followed by mood (12.3%), substance (10.4%), and disruptive behavior disorders (2.5%). Women had greater odds of anxiety and mood disorders; men had greater odds of substance disorders. Age-at-interview was inversely associated with lifetime risk of any disorder.

Discussion

The results provide direct evidence for high lifetime societal burdens of common mental disorders in Argentina due to a combination of high prevalence and early age-of-onset.

Keywords

Epidemiology Argentina Mental health Psychiatric disorder Lifetime prevalence 

Notes

Acknowledgements

The Argentinean Study of Mental Health Epidemiology was funded by the Ministerio de Salud de la Nación (Argentinean Ministry of Health) (Grant Number 2002–17270/13 − 5). This survey was carried out in conjunction with the World Health Organization World Mental Health (WMH) Survey Initiative. We thank the WMH staff for assistance with instrumentation and fieldwork.

Compliance with ethical standards

Conflict of interest

In the past 3 years, Dr. Kessler received support for his epidemiological studies from Sanofi Aventis; was a consultant for Johnson & Johnson Wellness and Prevention, Sage Pharmaceuticals, Shire, Takeda; and served on an advisory board for the Johnson & Johnson Services Inc. Lake Nona Life Project. Kessler is a co-owner of DataStat, Inc., a market research firm that carries out healthcare research. On behalf of all authors, the corresponding author states that none of the other authors have conflicts of interest.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Alfredo H. Cía
    • 1
  • Juan Carlos Stagnaro
    • 2
  • Sergio Aguilar Gaxiola
    • 3
  • Horacio Vommaro
    • 4
  • Gustavo Loera
    • 5
  • María Elena Medina-Mora
    • 6
  • Sebastían Sustas
    • 7
  • Corina Benjet
    • 6
  • Ronald C. Kessler
    • 8
  1. 1.Anxiety Clinic and Research CenterCiudad Autónoma de Buenos AiresArgentina
  2. 2.Department of Psychiatry and Mental Health, School of MedicineUniversity of Buenos AiresBuenos AiresArgentina
  3. 3.Center for Reducing Health Disparities, Davis School of MedicineUniversity of CaliforniaSacramentoUSA
  4. 4.School of MedicineUniversity of Buenos AiresBuenos AiresArgentina
  5. 5.Center for Reducing Health DisparitiesUniversity of California, DavisSacramentoUSA
  6. 6.National Institute of Psychiatry Ramón de la Fuente MuñizMexico CityMexico
  7. 7.Department of Public Health, School of MedicineUniversity of Buenos AiresBuenos AiresArgentina
  8. 8.Department of Health Care PolicyHarvard Medical SchoolBostonUSA

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