Consumption of low-fat dairy, but not whole-fat dairy, is inversely associated with depressive symptoms in Japanese adults

Abstract

Purpose

Dairy products have been reported to have various beneficial effects on human health. Although some previous studies have shown relationships between dairy consumption and depressive symptoms, the results of these studies were not consistent. This study aimed to investigate the association between frequency of low- and whole-fat dairy consumption, and depressive symptoms.

Methods

This cross-sectional study enrolled 1159 Japanese adults aged 19–83 years. Dietary intake was assessed using a brief self-administered diet history questionnaire. Depressive symptoms were evaluated by a self-rating depression scale (SDS) (the presence of depressive symptoms was defined as an SDS score ≥45 points). Logistic regression models were used to analyze the association between the frequency of low- and whole-fat dairy consumption and depressive symptoms.

Results

Higher frequency of low-fat dairy consumption was associated with a lower prevalence of depressive symptoms. In the final adjusted model, the odds ratios and 95% confidence intervals for prevalence of depressive symptoms when no consumption of low-fat dairy was compared to moderate (1–3 times per week) and high (≥4 times/week) frequencies of low-fat dairy consumption were 0.96 (0.71, 1.30) and 0.51 (0.35, 0.77), respectively (p for the trend = 0.004). No relationships were observed between the consumption of whole-fat dairy and depressive symptoms.

Conclusions

The current results indicate that a higher frequency of low-fat dairy consumption may be associated with a lower prevalence of depressive symptoms.

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References

  1. 1.

    Oh NS, Lee HA, Lee JY, Joung JY, Lee KB, Kim Y, Lee KW, Kim SH (2013) The dual effects of Maillard reaction and enzymatic hydrolysis on the antioxidant activity of milk proteins. J Dairy Sci 96(8):4899–4911. doi:10.3168/jds.2013-6613

    CAS  Article  PubMed  Google Scholar 

  2. 2.

    Haug A, Hostmark AT, Harstad OM (2007) Bovine milk in human nutrition–a review. Lipids Health Dis 6:25. doi:10.1186/1476-511X-6-25

    Article  PubMed  PubMed Central  Google Scholar 

  3. 3.

    Chatterton DE, Nguyen DN, Bering SB, Sangild PT (2013) Anti-inflammatory mechanisms of bioactive milk proteins in the intestine of newborns. Int J Biochem Cell Biol 45(8):1730–1747

    CAS  Article  PubMed  Google Scholar 

  4. 4.

    Soedamah-Muthu SS, Ding EL, Al-Delaimy WK, Hu FB, Engberink MF, Willett WC, Geleijnse JM (2011) Milk and dairy consumption and incidence of cardiovascular diseases and all-cause mortality: dose-response meta-analysis of prospective cohort studies. Am J Clin Nutr 93(1):158–171

    CAS  Article  PubMed  Google Scholar 

  5. 5.

    Tong X, Dong JY, Wu ZW, Li W, Qin LQ (2011) Dairy consumption and risk of type 2 diabetes mellitus: a meta-analysis of cohort studies. Eur J Clin Nutr 65(9):1027–1031

    CAS  Article  PubMed  Google Scholar 

  6. 6.

    Itabashi A (2006) [Prevention of osteoporosis by foods and dietary supplements. Milk basic protein (MBP) increases bone mineral density in young adult women and perimenopausal women]. Clin Calcium 16(10):1632–1638

    CAS  PubMed  Google Scholar 

  7. 7.

    Jauhiainen T, Korpela R (2007) Milk peptides and blood pressure. J Nutr 137(3 Suppl 2):825 S–829 S

    CAS  Google Scholar 

  8. 8.

    Ursin G, Bjelke E, Heuch I, Vollset SE (1990) Milk consumption and cancer incidence: a Norwegian prospective study. Br J Cancer 61(3):454–459

    CAS  Article  PubMed  Google Scholar 

  9. 9.

    Tseng M, Breslow RA, Graubard BI, Ziegler RG (2005) Dairy, calcium, and vitamin D intakes and prostate cancer risk in the national health and nutrition examination epidemiologic follow-up study cohort. Am J Clin Nutr 81(5):1147–1154

    CAS  PubMed  Google Scholar 

  10. 10.

    Hirschler V, Oestreicher K, Beccaria M, Hidalgo M, Maccallini G (2009) Inverse association between insulin resistance and frequency of milk consumption in low-income Argentinean school children. J Pediatr 154(1):101–105

    CAS  Article  PubMed  Google Scholar 

  11. 11.

    Valtonen M, Niskanen L, Kangas AP, Koskinen T (2005) Effect of melatonin-rich night-time milk on sleep and activity in elderly institutionalized subjects. Nord J Psychiatry 59(3):217–221

    Article  PubMed  Google Scholar 

  12. 12.

    Birnie K, Ben-Shlomo Y, Gunnell D, Ebrahim S, Bayer A, Gallacher J, Holly JM, Martin RM (2012) Childhood milk consumption is associated with better physical performance in old age. Age Ageing 41(6):776–784

    Article  PubMed  PubMed Central  Google Scholar 

  13. 13.

    Compton WM, Conway KP, Stinson FS, Grant BF (2006) Changes in the prevalence of major depression and comorbid substance use disorders in the United States between 1991–1992 and 2001–2002. Am J Psychiatry 163(12):2141–2147

    Article  PubMed  Google Scholar 

  14. 14.

    Sharpley CF, Agnew LL (2011) Cytokines and depression: findings, issues, and treatment implications. Rev Neurosci 22(3):295–302

    CAS  Article  PubMed  Google Scholar 

  15. 15.

    Dowlati Y, Herrmann N, Swardfager W, Liu H, Sham L, Reim EK, Lanctot KL (2010) A meta-analysis of cytokines in major depression. Biol Psychiatry 67(5):446–457

    CAS  Article  PubMed  Google Scholar 

  16. 16.

    Howren MB, Lamkin DM, Suls J (2009) Associations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysis. Psychosom Med 71(2):171–186

    CAS  Article  PubMed  Google Scholar 

  17. 17.

    Tsai AC, Chang TL, Chi SH (2012) Frequent consumption of vegetables predicts lower risk of depression in older Taiwanese - results of a prospective population-based study. Public Health Nutr 15(6):1087–1092

    Article  PubMed  Google Scholar 

  18. 18.

    Aihara Y, Minai J, Aoyama A, Shimanouchi S (2011) Depressive symptoms and past lifestyle among Japanese elderly people. Community Ment Health J 47(2):186–193

    Article  PubMed  Google Scholar 

  19. 19.

    Miyake Y, Tanaka K, Okubo H, Sasaki S, Arakawa M (2015) Intake of dairy products and calcium and prevalence of depressive symptoms during pregnancy in Japan: a cross-sectional study. BJOG 122(3):336–343

    CAS  Article  PubMed  Google Scholar 

  20. 20.

    The Japan International Center for Occupational Safety and Health (JICOSH). http://wwwjnioshgojp/icpro/jicosh-old/english/topics/OSHLegislationhtml. Accessed 25 Sept 2015

  21. 21.

    Guo H, Niu K, Monma H, Kobayashi Y, Guan L, Sato M, Minamishima D, Nagatomi R Association of Japanese dietary pattern with serum adiponectin concentration in Japanese adult men. Nutr Metab Cardiovasc Dis. doi:10.1016/j.numecd.2010.06.006

  22. 22.

    Zung WW (1969) A cross-cultural survey of symptoms in depression. Am J Psychiatry 126(1):116–121

    CAS  Article  PubMed  Google Scholar 

  23. 23.

    Zung WW, Richards CB, Short MJ (1965) Self-rating depression scale in an outpatient clinic. Further validation of the SDS. Arch Gen Psychiatry 13(6):508–515

    CAS  Article  PubMed  Google Scholar 

  24. 24.

    Fountoulakis KN, lacovides A, Samolis S, Kleanthous S, Kaprinis SG, St Kaprinis G, Bech P (2001) Reliability, validity and psychometric properties of the Greek translation of the Zung Depression Rating Scale. BMC Psychiatry 1:6

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  25. 25.

    Sasaki S, Ushio F, Amano K, Morihara M, Todoriki O, Uehara Y, Toyooka E (2000) Serum biomarker-based validation of a self-administered diet history questionnaire for Japanese subjects. J Nutr Sci Vitaminol (Tokyo) 46(6):285–296

    CAS  Article  Google Scholar 

  26. 26.

    Kobayashi S, Murakami K, Sasaki S, Okubo H, Hirota N, Notsu A, Fukui M, Date C (2011) Comparison of relative validity of food group intakes estimated by comprehensive and brief-type self-administered diet history questionnaires against 16 d dietary records in Japanese adults. Public Health Nutr 14(7):1200–1211

    Article  PubMed  Google Scholar 

  27. 27.

    Kobayashi S, Honda S, Murakami K, Sasaki S, Okubo H, Hirota N, Notsu A, Fukui M, Date C (2012) Both comprehensive and brief self-administered diet history questionnaires satisfactorily rank nutrient intakes in Japanese adults. J Epidemiol Jpn Epidemiol Assoc 22(2):151–159

    Article  Google Scholar 

  28. 28.

    Chaturvedi S (2004) The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7): is it really practical? Natl Med J India 17(4):227

    PubMed  Google Scholar 

  29. 29.

    Bassett DR Jr (2003) International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc 35(8):1396

    Article  PubMed  Google Scholar 

  30. 30.

    Delgado PL (2000) Depression: the case for a monoamine deficiency. J Clin Psychiatry 61(Suppl 6):7–11

    CAS  PubMed  Google Scholar 

  31. 31.

    Sanchez-Villegas A, Verberne L, De Irala J, Ruiz-Canela M, Toledo E, Serra-Majem L, Martinez-Gonzalez MA (2011) Dietary fat intake and the risk of depression: the SUN Project. PloS One 6(1):e16268. doi:10.1371/journal.pone.0016268

    CAS  Article  PubMed  PubMed Central  Google Scholar 

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Acknowledgements

We thank all participants and the Sendai Oroshisho Center for the possibility to perform the study. This study was supported by a Grant-in-Aid for “Knowledge Cluster Initiative” from the Ministry of Education, Culture, Sports, Science and Technology of Japan, and was partially supported by the Center of Innovation Program from Japan Science and Technology Agency, JST.

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Correspondence to Ryoichi Nagatomi.

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Cui, Y., Huang, C., Momma, H. et al. Consumption of low-fat dairy, but not whole-fat dairy, is inversely associated with depressive symptoms in Japanese adults. Soc Psychiatry Psychiatr Epidemiol 52, 847–853 (2017). https://doi.org/10.1007/s00127-016-1333-1

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Keywords

  • Cross-sectional study
  • Low-fat dairy
  • Consumption frequency
  • Depressive symptom