Abstract
Purpose
Our theoretical model proposes that insomnia, worry, and negative affect are important determinants of paranoid thinking. Anxiety produces anticipation of threat, depression increases the sense of vulnerability, worry leads to implausible ideas, and insomnia exacerbates negative affect and creates an altered perceptual state. The study objective was to examine for the first time these factors as predictors of the onset of new paranoid thinking and of the persistence of existing paranoid thinking.
Method
A total of 2,382 participants in the 2000 British National Psychiatric Morbidity Survey were followed-up 18 months after their first assessment. Baseline assessments were used to predict the development and persistence of paranoid thinking at follow-up. Data were weighted to be representative of the general household population.
Results
Insomnia, worry, anxiety, depression and depressive ideas were each substantial predictors both of new inceptions of paranoia and of the persistence of existing paranoid thinking. Worry and insomnia were the strongest predictors. For example, insomnia at the first assessment led to a more than threefold increase in later inceptions of paranoid thinking.
Conclusions
The study indicates that insomnia, worry, anxiety and depression are potential risk factors for new inceptions of paranoid thinking. The results also corroborate an emerging literature indicating that anxiety, worry and depression may encourage the persistence of paranoid thinking. The study provides the first longitudinal evidence linking insomnia and paranoia. The important clinical implication is that the use of interventions for common mental health difficulties in people with psychosis may have the additional benefit of reducing paranoia.
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References
Allardyce J, McCreadie RG, Morrison G, van Os J (2007) Do symptom dimensions or categorical diagnoses best discriminate between risk factors for psychosis. Soc Psychiatry Psychiatr Epidemiol 42:429–437
Bebbington PE, Nayani T (1995) The Psychosis Screening Questionnaire. Int J Methods Psychiatr Res 5:11–20
Bebbington PE, Wilkins S, Jones P, Forester A, Murray RM, Toone B, Lewis S (1993) Life events and psychosis: results from the Camberwell Collaborative Psychosis Study. Br J Psychiatry 162:72–79
Breslau N, Roth T, Rosenthal L, Andreski P (1996) Sleep disturbance and psychiatric disorders: a longitudinal epidemiological study of young adults. Biol Psychiatry 39:411–418
Claridge G (1997) Schizotypy: implications for illness and health. Oxford University Press, Oxford
First MB, Gibbon M, Spitzer RL, Williams JBW, Benjamin L (1997) Structured clinical interview for DSMIV axis ii personality disorders. American Psychiatric Press, Washington
Foster C, Startup H, Potts L, Freeman D (2010) A randomised controlled trial of a worry intervention for individuals with persistent persecutory delusions. J Behavior Ther Exp Psychiatry 41:45–51
Freeman D (2007) Suspicious minds: the psychology of persecutory delusions. Clin Psychol Rev 27:425–457
Freeman D (2011) Improving cognitive treatments for delusions. Schizophr Res. doi:10.1016/j.schres.2011.08.012
Freeman D, Brugha T, Meltzer H, Jenkins R, Stahl D, Bebbington P (2010) Persecutory ideation and insomnia: findings from the second British National Survey of Psychiatric Morbidity. J Psychiatr Res 44:1021–1026
Freeman D, Freeman J, Garety P (2008) Overcoming paranoid and suspicious thoughts. Basic Books, New York
Freeman D, Garety PA, Bebbington PE, Smith B, Rollinson R, Fowler D, Kuipers E, Ray K, Dunn G (2005) Psychological investigation of the structure of paranoia in a non-clinical population. Br J Psychiatry 186:427–435
Freeman D, Garety PA, Kuipers E, Fowler D, Bebbington PE (2002) A cognitive model of persecutory delusions. Br J Clin Psychol 41:331–347
Freeman D, McManus S, Brugha T, Meltzer H, Jenkins R, Bebbington P (2011) Concomitants of paranoia in the general population. Psychol Med 41:923–936
Freeman D, Pugh K, Antley A, Slater M, Bebbington P, Gittins M, Dunn G, Kuipers E, Fowler D, Garety PA (2008) A virtual reality study of paranoid thinking in the general population. Br J Psychiatry 192:258–263
Freeman D, Pugh K, Vorontsova N, Antley A, Slater M (2010) Testing the continuum of delusional beliefs. J Abnorm Psychol 119:83–92
Freeman D, Pugh K, Vorontsova N, Southgate L (2009) Insomnia and paranoia. Schizophr Res 108:280–284
Harrow M, Jobe T, Astrachan-Fletcher EB (2008) Prognosis of persecutory delusions in schizophrenia: a 20-year longitudinal study. In: Freeman D, Bentall R, Garety P (eds) Persecutory delusions. Oxford University Press, Oxford, pp 73–90
Hepworth C, Startup H, Freeman D (2011) Developing treatments for persistent persecutory delusions: the impact of an emotional processing and metacognitive awareness (EPMA) intervention. J Nerv Mental Dis 199:653–658
Jenkins R, Meltzer H, Bebbington P, Brugha T, Farrell M, McManus S, Singleton N (2009) The British Mental Health Survey Programme: achievements and latest findings. Soc Psychiatry Psychiatr Epidemiol 44:899–904
Jones P, Rodgers B, Murray R, Marmot M (1994) Child developmental risk factors for adult schizophrenia in the British 1946 birth cohort. Lancet 344:1398–1402
Kendler KS, Hettema JM, Butera F, Gardner CO, Prescott CA (2003) Life event dimensions of loss, humiliation, entrapment, and danger in the prediction of onsets of major depression and generalised anxiety. Arch Gen Psychiatry 60:789–796
Krabbendam L, Janssen I, Bijl RV, Vollebergh WAM, van Os J (2002) Neuroticism and low self-esteem as risk factors for psychosis. Soc Psychiatry Psychiatr Epidemiol 37:1–6
Larkin W, Morrison AP (eds) (2006) Trauma and Psychosis. Routledge, Hove
Lewis G, Pelosi A, Araya RC, Dunn G (1992) Measuring psychiatric disorder in the community: a standardised assessment for use by lay interviewers. Psychol Med 22:465–468
Lincoln TM, Lange J, Burau J, Exner C Moritz S (2010) The effect of state anxiety on paranoid ideation and jumping to conclusions. An experimental investigation. Schizophr Bull 36:1140–1148. doi:10.1093/schbul/sbp029
Lincoln TM, Peter N, Schäfer M, Moritz S (2008) Impact of stress on paranoia: an experimental investigation of moderators and mediators. Psychol Med 39:1129–1139
McGrath JJ (2007) The surprisingly rich contours of schizophrenia epidemiology. Arch Gen Psychiatry 64:14–16
Moffitt TE, Caspi A, Harrington H, Milne BJ, Melchior M, Goldberg D, Poulton R (2007) Generalised anxiety disorder and depression; childhood risk factors in a birth cohort followed to age 32. Psychol Med 37:441–452
Morphy H, Dunn KM, Lewis M, Boardman HF, Croft PR (2007) Epidemiology of insomnia: a longitudinal study in a UK population. Sleep 30:274–280
Myers E, Startup H, Freeman D (2011) Cognitive behavioural treatment of insomnia in individuals with persistent persecutory delusions. J Behav Ther Exp Psychiatry 42:330–336
Myin-Germeys I, van Os J (2007) Stress-reactivity in psychosis: evidence for an affective pathway to psychosis. Clin Psychol Rev 27:409–424
Peralta V, Cuesta MJ (1999) Dimensional structure of psychotic symptoms: an item-level analysis of SAPS and SANS symptoms in psychotic disorders. Schizophr Res 38:13–26
Shevlin M, Adamson G, Vollebergh W, de Graaf R, van Os J (2007) An application of item response mixture modelling to psychosis indicators in two large community samples. Soc Psychiatry Psychiatr Epidemiol 42:771–779
Singleton N, Bumpstead R, O’Brien M, Lee A, Meltze H (2001) Psychiatric morbidity among adults living in private households. TSO, London
Singleton N, Lewis G (2003) Better or worse: a longitudinal study of the Mental Health of Adults Living in Private Households in Great Britain. London, TSO
SPSS (2006) SPSS Base 15.0 User’s Guide. SPSS Inc., Chicago
Startup H, Freeman D, Garety PA (2007) Persecutory delusions and catastrophic worry in psychosis: developing the understanding of delusion distress and persistence. Behav Res Ther 45:523–537
Thewissen V, Bentall RP, Oorschot M, à Campo J, van Lierop T, van Os J, Myin-Germeys I (2011) Emotions, self-esteem, and paranoid episodes: an experience sampling study. Br J Clin Psychol 50:178–195. doi:10.1348/014466510X508677
Van Os J, Linscott RJ, Myin-Germeys I, Delespaul P, Krabbendam L (2009) A systematic review and meta-analysis of the psychosis continuum. Psychol Med 39:179–195
Vázquez-Barquero JL, Lastra I, Nuñez MJC, Castanedo SH, Dunn G (1996) Patterns of positive and negative symptoms in first episode schizophrenia. Br J Psychiatry 168:693–701
Wigman JTW, Vollebergh WAM, Raaijmakers QAW, Iedema J, van Dorsselaer S, Ormel J, Verhulst FC, van Os J (2011) The structure of the extended psychosis phenotype in early adolescence—a cross-sample replication. Schizophr Bull 37:850–860. doi:10.1093/schbul/sbp154
Wiles NJ, Zammit S, Bebbington P, Singleton N, Meltzer H, Lewis G (2006) Self-reported psychotic symptoms in the general population. Br J Psychiatry 188:519–526
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Daniel Freeman is supported by an MRC Senior Clinical Fellowship.
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Appendix: Items comprising the dimensional paranoia measure
Appendix: Items comprising the dimensional paranoia measure
Do you avoid getting involved with people unless you are certain that they will like you?
Do you find it hard to be ‘open’ even with people you are close to?
Do you often worry about being criticised or rejected in social situations?
Do you believe that you are not as good, as smart, or as attractive as most other people?
Do you find it hard to disagree with people even when you think they are wrong?
Do you often have to keep an eye out to stop people from using you or hurting you?
Do you spend a lot of time wondering if you can trust your friends or the people that you work with?
Do you find that it is best not to let other people know much about you because they will use it against you?
Do you often detect hidden threats or insults in things people say or do?
When you are out in public and see people talking, do you often feel that they are talking about you?
When you are around people, do you often get the feeling that you are being watched or stared at?
Over the past year, have you ever felt that your thoughts were directly interfered with or controlled by some outside force or person?
Over the past year, have there been times when you felt that people were against you?
Have there been times when you felt that people were deliberately acting to harm you or your interests?
Have there been times you felt that a group of people was plotting to cause you serious harm or injury?
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Freeman, D., Stahl, D., McManus, S. et al. Insomnia, worry, anxiety and depression as predictors of the occurrence and persistence of paranoid thinking. Soc Psychiatry Psychiatr Epidemiol 47, 1195–1203 (2012). https://doi.org/10.1007/s00127-011-0433-1
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DOI: https://doi.org/10.1007/s00127-011-0433-1