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Genome-wide association analysis to identify chromosomal regions determining components of earliness in wheat

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Abstract

The modification of flowering date is considered an important way to escape the current or future climatic constraints that affect wheat crops. A better understanding of its genetic bases would enable a more efficient and rapid modification through breeding. The objective of this study was to identify chromosomal regions associated with earliness in wheat. A 227-wheat core collection chosen to be highly contrasted for earliness was characterized for heading date. Experiments were conducted in controlled conditions and in the field for 3 years to break down earliness in the component traits: photoperiod sensitivity, vernalization requirement and narrow-sense earliness. Whole-genome association mapping was carried out using 760 molecular markers and taking into account the five ancestral group structure. We identified 62 markers individually associated to earliness components corresponding to 33 chromosomal regions. In addition, we identified 15 other significant markers and seven more regions by testing marker pair interactions. Co-localizations were observed with the Ppd-1, Vrn-1 and Rht-1 candidate genes. Using an independent set of lines to validate the model built for heading date, we were able to explain 34% of the variation using the structure and the significant markers. Results were compared with already published data using bi-parental populations giving an insight into the genetic architecture of flowering time in wheat.

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Acknowledgments

The authors acknowledge the experimental work carried out by Jean-Pierre Noclerq (INRA, Estrées-Mons). This work was partly supported by the “Agence Nationale de la Recherche” (ANR) Wheat Performance Project (ANR07-GPLA023).

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Authors and Affiliations

  1. INRA, UMR 1095 Génétique, Diversité et Ecophysiologie des Céréales, 234 Avenue du Brézet, 63 100, Clermont-Ferrand, France

    J. Le Gouis, J. Bordes, C. Ravel, F. Balfourier & V. Allard

  2. Université Blaise Pascal, UMR 1095 Génétique, Diversité et Ecophysiologie des Céréales, 63 177, Aubière Cedex, France

    J. Le Gouis, J. Bordes, C. Ravel, F. Balfourier & V. Allard

  3. INRA, UMR 1281 Stress Abiotiques et Différenciation des Végétaux Cultivés, Estrées-Mons, 80 203, Péronne, France

    E. Heumez

  4. BIOGEMMA, 8, rue des frères Lumière, 63 028, Clermont-Ferrand Cedex 02, France

    S. Faure & S. Praud

  5. INRA-UPS-CNRS-AgroParisTech, UMR de Génétique Végétale, Ferme du Moulon, 91190, Gif-sur-Yvette, France

    N. Galic, C. Remoué & M. Rousset

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  1. J. Le Gouis
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Correspondence to J. Le Gouis.

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Communicated by I. Mackay.

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Le Gouis, J., Bordes, J., Ravel, C. et al. Genome-wide association analysis to identify chromosomal regions determining components of earliness in wheat. Theor Appl Genet 124, 597–611 (2012). https://doi.org/10.1007/s00122-011-1732-3

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