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Operative Therapie von Wirbelsäulenmetastasen urologischer Tumoren

Operative therapy of spinal metastases from urological tumors

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Zusammenfassung

Die Behandlung von Knochenmetastasen urologischer Tumoren stellt – bis auf die Resektion solitärer Metastasen von Nierenzellkarzinomen – eine palliative Therapieform dar. Aufgrund der hohen Inzidenz von Wirbelkörpermetastasen können für den Patienten hierbei klinisch bedeutende Symptome und mögliche Komplikationen wie Schmerzen, eine Instabilität der Wirbelsäule oder eine Spinalkanalkompression mit entsprechenden neurologischen Ausfallserscheinungen resultieren. Durch gezielte Diagnostik und Einleitung strahlentherapeutischer und/oder chirurgischer Therapien kann bei einem Großteil der Patienten eine unmittelbare Schmerzreduktion, sowie eine frühzeitige Mobilisierung und teils auch eine Regredienz bestehender neurologischer Ausfallserscheinungen und somit eine bessere Lebensqualität erreicht werden.

Abstract

The treatment of bone metastases from urological tumors represents a palliative form of therapy, apart from the resection of solitary metastases from renal cell carcinomas. Due to the high incidence of spinal metastases this can result in clinically significant symptoms and possible complications for patients, such as pain, spinal instability and compression of the spinal canal with corresponding neurological deficits. By the use of targeted diagnostics and induction of radiotherapeutic and/or surgical treatment, for the majority of patients an immediate reduction in pain as well as early mobilization and sometimes even regression of existing neurological deficits and therefore an improved quality of life can be achieved.

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Einhaltung ethischer Richtlinien

Interessenkonflikt. R.H. Richter, M. Hammon, M. Uder, J. Huber, P.J. Goebell, F. Kunath, B. Wullich und B. Keck geben an, dass kein Interessenkonflikt besteht. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.

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Authors and Affiliations

  1. Orthopädische Universitätsklinik Erlangen, Friedrich-Alexander Universität Erlangen, Rathsberger Straße 57, 91054, Erlangen, Deutschland

    R.H. Richter

  2. Radiologisches Institut, Universitätsklinikum Erlangen, Erlangen, Deutschland

    M. Hammon & M. Uder

  3. Klinik und Poliklinik für Urologie, Medizinische Fakultät Carl Gustav Carus, TU Dresden, Dresden, Deutschland

    J. Huber

  4. Urologische Universitätsklinik Erlangen, Universitätsklinikum Erlangen, Erlangen, Deutschland

    P.J. Goebell, F. Kunath, B. Wullich & B. Keck

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  1. R.H. Richter
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  2. M. Hammon
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  3. M. Uder
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  7. B. Wullich
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Correspondence to R.H. Richter.

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Richter, R., Hammon, M., Uder, M. et al. Operative Therapie von Wirbelsäulenmetastasen urologischer Tumoren. Urologe 55, 232–240 (2016). https://doi.org/10.1007/s00120-015-3999-5

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  • DOI: https://doi.org/10.1007/s00120-015-3999-5

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