Zusammenfassung
Bei Patienten mit metastasiertem Hodentumor ist die Residualtumorresektion (RTR) nach Chemotherapie Therapie der Wahl. Sie kann entweder unilateral oder als ausgedehnte bilaterale RTR durchgeführt werden. Häufig werden zusätzliche Prozeduren notwendig, beispielsweise Nephrektomie, Splenektomie, Wirbelkörperersatz, Organteilresektionen wie Leberteilresektion oder partielle Darmresektion sowie Gefäßersatz. Entsprechend vielfältig können die intra- und postoperativen Komplikationen sein. In unserer Publikation gehen wir auf mögliche Früh- und Spätkomplikationen der RTR bei metastasierten Hodentumoren mit Behandlungs- und Vermeidungsstrategien ein.
Abstract
Residual tumor resection (RTR) in patients with metastatic testicular cancer plays a pivotal role in a multimodal treatment. It can be performed unilaterally or as an extended bilateral RTR. Additional surgical procedures might be necessary, such as nephrectomy, splenectomy, partial colectomy, or vascular interventions with possible caval resection, cavotomy, or aortic resection with aortic grafting. Consequently, several complications can be seen in the intra- and postoperative course, most common of which are superficial wound infections, intestinal paralysis, lymphocele, and chylous ascites. We sought to describe complication management and how to prevent complications before they arise.
Literatur
American Cancer Society (2014) Cancer facts & figures 2014. American Cancer Society, Atlanta
Stephenson AJ, Tal R, Sheinfeld J (2006) Adjunctive nephrectomy at post-chemotherapy retroperitoneal lymph node dissection for nonseminomatous germ cell testicular cancer. J Urol 176(5):1996–1999
Hendry WF, Norman AR, Dearnaley DP et al (2002) Metastatic nonseminomatous germ cell tumors of the testis: results of elective and salvage surgery for patients with residual retroperitoneal masses. Cancer 94(6):1668–1676
Winter C, Pfister D, Busch J et al (2012) Residual tumor size and IGCCCG risk classification predict additional vascular procedures in patients with germ cell tumors and residual tumor resection: a multicenter analysis of the German Testicular Cancer Study Group. Eur Urol 61(2):403–409
Albers P, Bingoel C, Witthuhn R et al (2009) Complications of postchemotherapy residual tumor resection in patients with germ cell cancer. J Clin Oncol 27 (Suppl):e16077
Baniel J, Foster RS, Rowland RG et al (1995) Complications of post-chemotherapy retroperitoneal lymph node dissection. J Urol 153(3 Pt 2):976–980
Luz MA, Kotb AF, Aldousari S et al (2010) Retroperitoneal lymph node dissection for residual masses after chemotherapy in nonseminomatous germ cell testicular tumor. World J Surg Oncol 8:97. DOI 10.1186/1477-7819-8-97
Heidenreich A, Ohlmann C, Hegele A (2005) Repeat retroperitoneal lymphadenectomy in advanced testicular cancer. Eur Urol 47(1):64–71
Donohue JP, Thornhill JA, Foster RS et al (1993) Retroperitoneal lymphadenectomy for clinical stage A testis cancer (1965–1989): modifications of technique and impact on ejaculation. J Urol 149:237–243
Heidenreich A, Albers P, Hartmann M et al (2003) Complications of primary nerve sparing retroperitoneal lymph node dissection for clinical stage I nonseminomatous germ cell tumors of the testis: experience of the German Testicular Cancer Study Group. J Urol 169(5):1710–1714
Leibovitch I, Mor Y, Golomb J et al (2002) The diagnosis and management of postoperative chylous ascites. J Urol 167:449–457
Mosharafa AA, Foster RS, Koch MO et al (2004) Complications of post-chemotherapy retroperitoneal lymph node dissection for testis cancer. J Urol 171:1839–1841
Goldiner PL, Schweizer O (1979) The hazards of anesthesia and surgery in bleomycin-treated patients. Semin Oncol 6(1):121–124
Djaladat H, Nichols C, Daneshmand S (2012) Adjuvant surgery in testicular cancer patients undergoing postchemotherapy retroperitoneal lymph node dissection. Ann Surg Oncol 19(7):2388–2393
Cary KC, Beck S, Bihrle R et al (2013) Clinical and pathological features predictive of nephrectomy at post-chemotherapy retroperitoneal lymph node dissection. J Urol 189(3):812–817
Winter C, Pfister D, Bingoel C et al (2011) Predictive factors for additional vascular procedures in patients with germ cell tumors (GCT) and residual tumor resection (RTR): A multicenter analysis of the german testicular cancer study groups (GTCSG). J Clin Oncol 29(Suppl):e15050
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Interessenkonflikt. A. Lusch, M. Zaum, C. Winter und P. Albers geben an, dass kein Interessenkonflikt besteht. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.
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Lusch, A., Zaum, M., Winter, C. et al. Komplikationsmanagement nach Residualtumorresektion bei metastasiertem Hodentumor. Urologe 53, 991–995 (2014). https://doi.org/10.1007/s00120-014-3502-8
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DOI: https://doi.org/10.1007/s00120-014-3502-8