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Seminom klinisches Stadium I

Neuer Therapiestandard Surveillance?

Clinical stage I seminoma

Is surveillance a new therapy standard?

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Zusammenfassung

Hintergrund

Die Therapie des Seminoms im klinischen Stadium I ist einem steten Wandel unterworfen. Wurden Surveillance, adjuvante Strahlentherapie und adjuvante Chemotherapie bis vor wenigen Jahren als weitgehend gleichberechtigte Therapiealternativen angesehen, machen aktuell publizierte Studien eine differenziertere Betrachtungsweise notwendig.

Diskussion

Die Übersicht diskutiert die jüngsten Daten zu möglichen Spätfolgen adjuvanter Strahlen- und Chemotherapie, die Frage einer Risikostratifizierung sowie die Vorteile und Limitationen einer Surveillancestrategie.

Abstract

Background

The therapy of stage I seminoma is under constant change. While surveillance, adjuvant radiotherapy and adjuvant chemotherapy were seen as equal therapeutic alternatives up to a few years ago, recently published studies make it necessary to adopt a more differentiated approach.

Discussion

In this review, recent data on the long-term effects of adjuvant radiotherapy and chemotherapy, the question of risk stratification as well as the advantages and limitations of a surveillance strategy are discussed.

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Einhaltung ethischer Richtlinien

Interessenkonflikt. F. Zengerling, J. Müller, A.J. Schrader und M. Schrader geben an, dass kein Interessenkonflikt besteht. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.

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Authors and Affiliations

  1. Klinik für Urologie und Kinderurologie, Universitätsklinikum Ulm, Prittwitzstraße 43, 89075, Ulm, Deutschland

    F. Zengerling, J. Müller, A.J. Schrader &  M. Schrader

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  1. F. Zengerling
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  2. J. Müller
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  3. A.J. Schrader
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  4. M. Schrader
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Correspondence to M. Schrader.

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Zengerling, F., Müller, J., Schrader, A. et al. Seminom klinisches Stadium I. Urologe 52, 1265–1269 (2013). https://doi.org/10.1007/s00120-013-3319-x

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  • DOI: https://doi.org/10.1007/s00120-013-3319-x

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