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Kaplan-Meier-Analysen in der urologischen Praxis

Kaplan-Meier analysis in urological practice

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Zusammenfassung

Kaplan-Meier-Kurven und Überlebensschätzungen sind gängige Methoden Überlebensdaten in der Medizin zu präsentieren, insbesondere wenn das Follow-up der Studienteilnehmer unterschiedliche Längen besitzt. Unabhängig von Überlebensanalysen werden Kaplan-Meier-Kurven generell auch zur graphischen Darstellung anderer zeitgebundener Ereignisse verwendet. Ein grundlegendes Verständnis der Erstellung, Analyse und Interpretation von Kaplan-Meier-Kurven ist daher von großem Interesse, um eine adäquate Auswertung der urologischen Literatur in der täglichen Praxis sicherzustellen. Dieser Artikel fasst Basisprinzipien der Kaplan-Meier-Analyse sowie mögliche Schwierigkeiten und Varianten zusammen. Ein gutes Verständnis der Interpretation von Kaplan-Meier-Analysen kann zur Verbesserung der evidenzbasierten Urologie beitragen.

Abstract

Kaplan-Meier curves and estimates of survival are the most common way to present survival data in medicine, especially for cohorts with different lengths of follow-up. Moreover, Kaplan-Meier curves present a frequently used general graphic approach to display time-to-event outcomes. A solid understanding of how Kaplan-Meier curves are generated and how they should be analyzed and interpreted is of great importance to appraise urological literature in daily clinical practice. This article describes the basic principles of Kaplan-Meier analysis, possible variants and pitfalls. Improved knowledge of Kaplan-Meier analysis can help to improve Evidence-based urology and its application in patient care.

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Der korrespondierende Autor gibt für sich und seine Koautoren an, dass kein Interessenkonflikt besteht.

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Authors and Affiliations

  1. Klinik und Poliklinik für Urologie, Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Deutschland

    M. Rink, L.A. Kluth, M. Fisch & R. Dahlem

  2. Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY, USA

    L.A. Kluth & S.F. Shariat

  3. Division of Medical Oncology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY, USA

    S.F. Shariat

  4. Department of Urology, University of Florida, College of Medicine, Gainesville, FL, USA

    P. Dahm

Authors
  1. M. Rink
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  2. L.A. Kluth
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  3. S.F. Shariat
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  4. M. Fisch
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  5. R. Dahlem
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  6. P. Dahm
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Corresponding author

Correspondence to M. Rink.

Additional information

Dr. Michael Rink und Dr. Luis A. Kluth waren zu gleichen Teilen an der Manuskripterstellung beteiligt.Ein Beitrag zur Serie „Evidenz-basierte Urologie“. Redaktion: P. Dahm und M. Rink.

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Rink, M., Kluth, L., Shariat, S. et al. Kaplan-Meier-Analysen in der urologischen Praxis. Urologe 52, 838–841 (2013). https://doi.org/10.1007/s00120-013-3150-4

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  • DOI: https://doi.org/10.1007/s00120-013-3150-4

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