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Die „likelihood ratio“

Beeinflussung der Therapieentscheidung durch einen diagnostischen Test

The likelihood ratio

Estimation of the impact of a diagnostic test on treatment decision

Der Urologe volume 52, pages 982–985 (2013)Cite this article

Zusammenfassung

„Likelihood ratios“ (LR) erlauben dem Kliniker einfach und schnell die Umrechnung der Vortest- zur Nachtestwahrscheinlichkeit einer bestimmten Erkrankung, basierend auf der erbrachten Information eines bestimmten Tests. Auf diese Weise kann der diagnostische Nutzen eines bestimmten Tests für eine bestimmte klinische Fragestellung eruiert werden. Entsprechend können LR auch dafür verwendet werden, die Leistungsfähigkeit zwischen verschiedenen diagnostischen Tests zu vergleichen. Urologen sollten sich mit dem Gebrauch der LR vertraut machen, um eine evidenzbasierte Anwendung diagnostischer Tests für ihre Patienten zu fördern. In diesem Review soll die Berechnung und Verwendung der LR verdeutlicht werden.

Abstract

Likelihood ratios (LRs) can be used to assess in an efficient manner the change of a pre-test probability to the post-test probability of a disease based on a given test result. For any clinical question or condition of interest, the diagnostic benefit can be calculated for each diagnostic test allowing to compare the performance of different diagnostic tests. Urologists should become familiar with the use of LR to promote a more evidence-based application of diagnostic test for different clinical scenarios. This review provides insights in the calculation and use of LR.

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Interessenkonflikt

Der korrespondierende Autor gibt für sich und seine Koautoren an, dass kein Interessenkonflikt besteht.

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Affiliations

  1. Klinik für Urologie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland

    L.A. Kluth, M. Rink, F.K.H. Chun & M. Fisch

  2. Department of Urology, Weill Medical College of Cornell University, 525 East 68th Street, Starr 900, 10065, New York, NY, USA

    L.A. Kluth, M. Rink & S.F. Shariat MD

  3. Division of Medical Oncology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY, USA

    S.F. Shariat MD

  4. Department of Urology, University of Florida, College of Medicine, Gainesville, FL, USA

    P. Dahm

Authors
  1. L.A. Kluth
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  2. M. Rink
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  3. F.K.H. Chun
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  4. M. Fisch
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  5. S.F. Shariat MD
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  6. P. Dahm
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Corresponding author

Correspondence to S.F. Shariat MD.

Additional information

Dr. Luis A. Kluth und Dr. Michael Rink waren zu gleichen Teilen an der Manuskripterstellung beteiligt.

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Kluth, L., Rink, M., Chun, F. et al. Die „likelihood ratio“. Urologe 52, 982–985 (2013). https://doi.org/10.1007/s00120-013-3145-1

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  • DOI: https://doi.org/10.1007/s00120-013-3145-1

Schlüsselwörter

  • Diagnostischer Test
  • Blasenkarzinom
  • Lymphknoten
  • Evidenzbasierte Medizin

Keywords

  • Diagnostic test
  • Bladder cancer
  • Lymph node
  • Evidence-based urology