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Benignes Prostatasyndrom

Chirurgische Therapieoptionen

Benign prostatic hyperplasia (BPH)

Surgical therapy options

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Zusammenfassung

Die chirurgischen Therapieoptionen zur Behandlung des benignen Prostatasyndroms (BPS) können heute in sehr differenzierter Form betrachtet werden. Die instrumentellen Verfahren werden oft nach vorangegangener medikamentöser Therapie eingesetzt. Neben der seit Jahrzehnten bewährten Standardmethode, der transurethralen Resektion der Prostata (TURP), und deren Modifikationen wie der bipolaren Resektion verschiebt sich der Fokus des Interesses zunehmend auf alternative, so genannte minimalinvasive Verfahren wie transurethrale Mikrowellentherapie (TUMT) oder, in letzter Zeit besonders, lasergestützte Operationstechniken. Unter Zuhilfenahme der aktuellen Datenlage, vorzugsweise aus randomisierten kontrollierten Studien, wird zu den einzelnen Verfahren kritisch Stellung bezogen.

Abstract

The surgical treatment options available today for benign prostatic hyperplasia (BPH) can take various forms and often follow a course of pharmacological therapy. In addition to conventional transurethral resection of the prostate (TURP) and its modifications (bipolar resection), which has represented the standard therapeutic option for decades, the focus of research and clinical application has shifted to alternative so-called “minimally invasive” instrumental techniques, such as transurethral microwave therapy (TUMT) and, particularly more recently, to the different laser-assisted techniques. By reviewing the current literature, preferably from randomized controlled trials, critical appraisals of the individual procedures are made.

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Literatur

  1. Adam C, Hofstetter A, Deubner J et al (2004) Retropubic transvesical prostatectomy for significant prostatic enlargement must remain a standard part of urology training. Scand J Urol Nephrol 38:472–476

    Article  PubMed  Google Scholar 

  2. Alivizatos G, Skolarikos A, Chalikopoulos D et al (2008) Transurethral photoselective vaporization versus transvesical open enucleation for prostatic adenomas >80 ml: 12-mo results of a randomized prospective study. Eur Urol 54:427–437

    Article  PubMed  Google Scholar 

  3. Alschibaja M, May F, Treiber U et al (2005) Transurethral resection for benign prostatic hyperplasia. current developments. Urologe A 44:499–504

    Article  CAS  PubMed  Google Scholar 

  4. AUA Practice Guidelines Committee (2003) AUA guideline on management of benign prostatic hyperplasia (2003). Chapter 1: Diagnosis and treatment recommendations. J Urol 170:530–547

    Article  Google Scholar 

  5. Bach T, Wendt-Nordahl G, Michel MS et al (2009) Feasibility and efficacy of Thulium:YAG laser enucleation (VapoEnucleation) of the prostate. World J Urol 27:541–545

    Article  CAS  PubMed  Google Scholar 

  6. Bachmann A, Reich O, Wyler S et al (2004) The 80 W potassium-titanium-phosphate (KTP) laser vaporization of the prostate. Technique and 6 month follow-up after 70 procedures. Urologe A 43:1262–1270

    Article  CAS  PubMed  Google Scholar 

  7. Bachmann A, Ruszat R, Wyler S et al (2005) Photoselective vaporization of the prostate: the basel experience after 108 procedures. Eur Urol 47:798–804

    Article  PubMed  Google Scholar 

  8. Bachmann A, Schurch L, Ruszat R et al (2005) Photoselective Vaporization (PVP) versus Transurethral Resection of the Prostate (TURP): A Prospective Bi-Centre Study of Perioperative Morbidity and Early Functional Outcome. Eur Urol

  9. Barmoshe S, Zlotta AR (2006) How do I treat and follow my TUNA patients? World J Urol 24:397–404

    Article  PubMed  Google Scholar 

  10. Bartoletti R, Cai T, Tinacci G et al (2008) Transperineal microwave thermoablation in patients with obstructive benign prostatic hyperplasia: a phase I clinical study with a new mini-choked microwave applicator. J Endourol 22:1509–1517

    Article  PubMed  Google Scholar 

  11. Baumert H, Ballaro A, Dugardin F et al (2006) Laparoscopic versus open simple prostatectomy: a comparative study. J Urol 175:1691–1694

    Article  CAS  PubMed  Google Scholar 

  12. Berges R, Dreikorn K, Hofner K et al (2009) Diagnostic and differential diagnosis of benign prostate syndrome (BPS): Guidelines of the German Urologists. Urologe A: 9.9.2009 [Epub ahead of print]

    Google Scholar 

  13. Blew BD, Fazio LM, Pace K et al (2005) Laparoscopic simple prostatectomy. Can J Urol 12:2891–2894

    PubMed  Google Scholar 

  14. Bouchier-Hayes DM, Anderson P, Van Appledorn S et al (2006) KTP laser versus transurethral resection: early results of a randomized trial. J Endourol 20:580–585

    Article  PubMed  Google Scholar 

  15. Boyle P, Robertson C, Vaughan ED et al (2004) A meta-analysis of trials of transurethral needle ablation for treating symptomatic benign prostatic hyperplasia. BJU Int 94:83–88

    Article  PubMed  Google Scholar 

  16. Chapple CR, Issa MM, Woo H (1999) Transurethral needle ablation (TUNA). A critical review of radiofrequency thermal therapy in the management of benign prostatic hyperplasia. Eur Urol 35:119–128

    Article  CAS  PubMed  Google Scholar 

  17. D’ancona FC (2008) Nonablative minimally invasive thermal therapies in the treatment of symptomatic benign prostatic hyperplasia. Curr Opin Urol 18:21–27

    Article  Google Scholar 

  18. Daehlin L, Frugard J (2000) Transurethral microwave thermotherapy in the management of lower urinary tract symptoms from benign prostatic obstruction: follow-up after five years. Scand J Urol Nephrol 34:304–308

    Article  CAS  PubMed  Google Scholar 

  19. De SM, Autorino R, Quarto G et al (2006) Gyrus bipolar versus standard monopolar transurethral resection of the prostate: a randomized prospective trial. Urology 67:69–72

    Article  Google Scholar 

  20. Desai MM, Aron M, Canes D et al (2008) Single-port transvesical simple prostatectomy: initial clinical report. Urology 72:960–965

    Article  PubMed  Google Scholar 

  21. Dineen MK, Shore ND, Lumerman JH et al (2008) Use of a temporary prostatic stent after transurethral microwave thermotherapy reduced voiding symptoms and bother without exacerbating irritative symptoms. Urology 71:873–877

    Article  PubMed  Google Scholar 

  22. Dunsmuir WD, Mcfarlane JP, Tan A et al (2003) Gyrus bipolar electrovaporization vs transurethral resection of the prostate: a randomized prospective single-blind trial with 1 y follow-up. Prostate Cancer Prostatic Dis 6:182–186

    Article  CAS  PubMed  Google Scholar 

  23. Elzayat EA, Elhilali MM (2006) Holmium laser enucleation of the prostate (HoLEP): the endourologic alternative to open prostatectomy. Eur Urol 49:87–91

    Article  PubMed  Google Scholar 

  24. Elzayat EA, Habib EI, Elhilali MM (2005) Holmium laser enucleation of the prostate: a size-independent new „gold standard“. Urology 66:108–113

    Article  PubMed  Google Scholar 

  25. Erol A, Cam K, Tekin A et al (2009) High power diode laser vaporization of the prostate: preliminary results for benign prostatic hyperplasia. J Urol 182:1078–1082

    Article  CAS  PubMed  Google Scholar 

  26. Freyer PJ (1912) One thousand cases of total enucleation of the prostate for radical cure of enlargement of that organ. Br Med J 2:868

    Article  Google Scholar 

  27. Fried NM (2005) High-power laser vaporization of the canine prostate using a 110 W Thulium fiber laser at 1.91 microm. Lasers Surg Med 36:52–56

    Article  PubMed  Google Scholar 

  28. Fung BT, Li SK, Yu CF et al (2005) Prospective randomized controlled trial comparing plasmakinetic vaporesection and conventional transurethral resection of the prostate. Asian J Surg 28:24–28

    PubMed  Google Scholar 

  29. Gilling PJ, Mackey M, Cresswell M et al (1999) Holmium laser versus transurethral resection of the prostate: a randomized prospective trial with 1-year followup. J Urol 162:1640–1644

    Article  CAS  PubMed  Google Scholar 

  30. Gratzke C, Schlenker B, Seitz M et al (2007) Complications and early postoperative outcome after open prostatectomy in patients with benign prostatic enlargement: results of a prospective multicenter study. J Urol 177:1419–1422

    Article  PubMed  Google Scholar 

  31. Gravas S, Melekos MD (2007) Transurethral microwave thermotherapy: from evidence-based medicine to clinical practice. Curr Opin Urol 17:12–16

    Article  PubMed  Google Scholar 

  32. Gupta N, Sivaramakrishna, Kumar R et al (2006) Comparison of standard transurethral resection, transurethral vapour resection and holmium laser enucleation of the prostate for managing benign prostatic hyperplasia of >40 g. BJU Int 97:85–89

    Article  PubMed  Google Scholar 

  33. Hai MA (2009) Photoselective vaporization of prostate: five-year outcomes of entire clinic patient population. Urology 73:807–810

    Article  PubMed  Google Scholar 

  34. Hai MA, Malek RS (2003) Photoselective vaporization of the prostate: initial experience with a new 80 W KTP laser for the treatment of benign prostatic hyperplasia. J Endourol 17:93–96

    Article  PubMed  Google Scholar 

  35. Hamann MF, Naumann CM, Seif C et al (2008) Functional outcome following photoselective vaporisation of the prostate (PVP): urodynamic findings within 12 months follow-up. Eur Urol 54:902–907

    Article  PubMed  Google Scholar 

  36. Hargreave TB, Heynes CF, Kendrick SW et al (1996) Mortality after transurethral and open prostatectomy in Scotland. Br J Urol 77:547–553

    CAS  PubMed  Google Scholar 

  37. Herrmann TR, Gross AJ, Schultheiss D et al (2006) Transurethral microwave thermotherapy for the treatment of BPH: still a challenger? World J Urol 24:389–396

    Article  CAS  PubMed  Google Scholar 

  38. Hoffman RM, Macdonald R, Monga M et al (2004) Transurethral microwave thermotherapy vs transurethral resection for treating benign prostatic hyperplasia: a systematic review. BJU Int 94:1031–1036

    Article  PubMed  Google Scholar 

  39. Hoffman RM, Monga M, Elliot SP et al (2007) Microwave thermotherapy for benign prostatic hyperplasia. Cochrane Database Syst Rev:CD004135

    Google Scholar 

  40. Holman CD, Wisniewski ZS, Semmens JB et al (1999) Mortality and prostate cancer risk in 19,598 men after surgery for benign prostatic hyperplasia. BJU Int 84:37–42

    Article  CAS  PubMed  Google Scholar 

  41. Holtgrewe HL, Valk WL (1962) Factors influencing the mortality and morbidity of transurethral prostatectomy: a study of 2,015 cases. J Urol 87:450–459

    CAS  PubMed  Google Scholar 

  42. Horasanli K, Silay MS, Altay B et al (2008) Photoselective potassium titanyl phosphate (KTP) laser vaporization versus transurethral resection of the prostate for prostates larger than 70 mL: a short-term prospective randomized trial. Urology 71:247–251

    Article  PubMed  Google Scholar 

  43. Horninger W, Unterlechner H, Strasser H et al (1996) Transurethral prostatectomy: mortality and morbidity. Prostate 28:195–200

    Article  CAS  PubMed  Google Scholar 

  44. John H, Bucher C, Engel N et al (2009) Preperitoneal robotic prostate adenomectomy. Urology 73:811–815

    Article  PubMed  Google Scholar 

  45. Kaye JD, Smith AD, Badlani GH et al (2008) High-energy transurethral thermotherapy with CoreTherm approaches transurethral prostate resection in outcome efficacy: a meta-analysis. J Endourol 22:713–718

    Article  PubMed  Google Scholar 

  46. Knutson T, Johansson A, Damber JE et al (2009) Intraurethral prostate injections with mepivacaine epinephrine: effects on patient comfort, treatment time and energy consumption during high-energy transurethral microwave thermotherapy. Scand J Urol Nephrol 43:300–306

    Article  CAS  PubMed  Google Scholar 

  47. Koshiba K, Egawa S, Ohori M et al (1995) Does transurethral resection of the prostate pose a risk to life? 22-year outcome. J Urol 153:1506–1509

    Article  CAS  PubMed  Google Scholar 

  48. Kuo RL, Paterson RF, Siqueira TM Jr et al (2005) High-powered holmium-laser ablation: comparison of setting effectiveness using tissue-surrogate model. J Endourol 19:239–241

    Article  PubMed  Google Scholar 

  49. Leonardi R (2009) Preliminary results on selective light vaporization with the side-firing 980 nm diode laser in benign prostatic hyperplasia: an ejaculation sparing technique. Prostate Cancer Prostatic Dis 12:277–280

    Article  CAS  PubMed  Google Scholar 

  50. Madersbacher S, Alivizatos G, Nordling J et al (2004) EAU 2004 guidelines on assessment, therapy and follow-up of men with lower urinary tract symptoms suggestive of benign prostatic obstruction (BPH guidelines). Eur Urol 46:547–554

    Article  PubMed  Google Scholar 

  51. Madersbacher S, Lackner J, Brossner C et al (2005) Reoperation, myocardial infarction and mortality after transurethral and open prostatectomy: a nation-wide, long-term analysis of 23,123 cases. Eur Urol 47:499–504

    Article  PubMed  Google Scholar 

  52. Madersbacher S, Marberger M (1999) Is transurethral resection of the prostate still justified? BJU Int 83:227–237

    Article  CAS  PubMed  Google Scholar 

  53. Malek RS, Kuntzman RS, Barrett DM (2005) Photoselective potassium-titanyl-phosphate laser vaporization of the benign obstructive prostate: observations on long-term outcomes. J Urol 174:1344–1348

    Article  PubMed  Google Scholar 

  54. Mamoulakis C, Ubbink DT, De La Rosette JJ (2009) Bipolar versus monopolar transurethral resection of the prostate: a systematic review and meta-analysis of randomized controlled trials. Eur Urol: 7.7.2009 [Epub ahead of print]

    Google Scholar 

  55. Mariano MB, Graziottin TM, Tefilli MV (2002) Laparoscopic prostatectomy with vascular control for benign prostatic hyperplasia. J Urol 167:2528–2529

    Article  PubMed  Google Scholar 

  56. Mariano MB, Tefilli MV, Graziottin TM et al (2006) Laparoscopic prostatectomy for benign prostatic hyperplasia – a six-year experience. Eur Urol 49:127–131

    Article  PubMed  Google Scholar 

  57. Matlaga BR, Kim SC, Kuo RL et al (2006) Holmium laser enucleation of the prostate for prostates of >125 mL. BJU Int 97:81–84

    Article  PubMed  Google Scholar 

  58. Mccullough TC, Heldwein FL, Soon SJ et al (2009) Laparoscopic versus open simple prostatectomy: an evaluation of morbidity. J Endourol 23:129–133

    Article  PubMed  Google Scholar 

  59. Mearini E, Marzi M, Mearini L et al (1998) Open prostatectomy in benign prostatic hyperplasia: 10-year experience in Italy. Eur Urol 34:480–485

    Article  CAS  PubMed  Google Scholar 

  60. Millin T (1947) Retropubic urinary surgery. E&S Livingstone, Edinburgh

  61. Montorsi F, Naspro R, Salonia A et al (2004) Holmium laser enucleation versus transurethral resection of the prostate: results from a 2-center, prospective, randomized trial in patients with obstructive benign prostatic hyperplasia. J Urol 172:1926–1929

    Article  PubMed  Google Scholar 

  62. Moody JA, Lingeman JE (2001) Holmium laser enucleation for prostate adenoma greater than 100 gm.: comparison to open prostatectomy. J Urol 165:459–462

    Article  CAS  PubMed  Google Scholar 

  63. Nadler RB, Blunt LW Jr, User HM et al (2004) Preperitoneal laparoscopic simple prostatectomy. Urology 63:778–779

    Article  PubMed  Google Scholar 

  64. Naspro R, Bachmann A, Gilling P et al (2009) A review of the recent evidence (2006–2008) for 532-nm photoselective laser vaporisation and holmium laser enucleation of the prostate. Eur Urol 55:1345–1357

    Article  PubMed  Google Scholar 

  65. Ott V (2005) Evaluation der Dissektionseigenschaften eines cw Thulium-YAG Lasersystems für den Einsatz in der laparoskopischen Kolonresektion. Inauguraldissertation zur Erlangung der Doktorwürde der Universität zu Lübeck – Einleitung und Problemstellung:5–21

  66. Pfitzenmaier J, Gilfrich C, Pritsch M et al (2008) Vaporization of prostates of >or =80 mL using a potassium-titanyl-phosphate laser: midterm-results and comparison with prostates of <80 mL. BJU Int 102:322–327

    Article  CAS  PubMed  Google Scholar 

  67. Porpiglia F, Terrone C, Renard J et al (2006) Transcapsular adenomectomy(Millin): a comparative study, extraperitoneal laparoscopy versus open surgery. Eur Urol 49:120–126

    Article  PubMed  Google Scholar 

  68. Rehman J, Khan SA, Sukkarieh T et al (2005) Extraperitoneal laparoscopic prostatectomy (adenomectomy) for obstructing benign prostatic hyperplasia: transvesical and transcapsular (Millin) techniques. J Endourol 19:491–496

    Article  PubMed  Google Scholar 

  69. Reich O, Bachmann A, Siebels M et al (2005) High power (80 W) potassium-titanyl-phosphate laser vaporization of the prostate in 66 high risk patients. J Urol 173:158–160

    PubMed  Google Scholar 

  70. Reich O, Gratzke C, Bachmann A et al (2008) Morbidity, mortality and early outcome of transurethral resection of the prostate: a prospective multicenter evaluation of 10,654 patients. J Urol 180:246–249

    Article  PubMed  Google Scholar 

  71. Reich O, Schlenker B, Gratzke C et al (2009) Plasma vaporisation of the prostate: Initial clinical results. Eur Urol: 26.5.2009 [Epub ahead of print]

    Google Scholar 

  72. Roehrborn CG, Issa MM, Bruskewitz RC et al (1998) Transurethral needle ablation for benign prostatic hyperplasia: 12-month results of a prospective, multicenter U.S. study. Urology 51:415–421

    Article  CAS  PubMed  Google Scholar 

  73. Roos NP, Wennberg JE, Malenka DJ et al (1989) Mortality and reoperation after open and transurethral resection of the prostate for benign prostatic hyperplasia. N Engl J Med 320:1120–1124

    Article  CAS  PubMed  Google Scholar 

  74. Ruszat R, Seitz M, Wyler SF et al (2009) Prospective single-centre comparison of 120-W diode-pumped solid-state high-intensity system laser vaporization of the prostate and 200-W high-intensive diode-laser ablation of the prostate for treating benign prostatic hyperplasia. BJU Int 104:820–825

    Article  CAS  PubMed  Google Scholar 

  75. Sandhu JS, Ng C, Vanderbrink BA et al (2004) High-power potassium-titanyl-phosphate photoselective laser vaporization of prostate for treatment of benign prostatic hyperplasia in men with large prostates. Urology 64:1155–1159

    Article  PubMed  Google Scholar 

  76. Sarica K, Alkan E, Luleci H et al (2005) Photoselective vaporization of the enlarged prostate with KTP laser: long-term results in 240 patients. J Endourol 19:1199–1202

    Article  PubMed  Google Scholar 

  77. Schatzl G, Madersbacher S, Djavan B et al (2000) Two-year results of transurethral resection of the prostate versus four ‚less invasive‘ treatment options. Eur Urol 37:695–701

    Article  CAS  PubMed  Google Scholar 

  78. Seitz M, Bayer T, Ruszat R et al (2009) Preliminary evaluation of a novel side-fire diode laser emitting light at 940 nm, for the potential treatment of benign prostatic hyperplasia: ex-vivo and in-vivo investigations. BJU Int 103:770–775

    Article  PubMed  Google Scholar 

  79. Seitz M, Reich O, Gratzke C et al (2009) High-power diode laser at 980 nm for the treatment of benign prostatic hyperplasia: ex vivo investigations on porcine kidneys and human cadaver prostates. Lasers Med Sci 24:172–178

    Article  PubMed  Google Scholar 

  80. Seitz M, Ruszat R, Bayer T et al (2009) Ex vivo and in vivo investigations of the novel 1,470 nm diode laser for potential treatment of benign prostatic enlargement. Lasers Med Sci 24:419–424

    Article  PubMed  Google Scholar 

  81. Seitz M, Sroka R, Gratzke C et al (2007) The diode laser: a novel side-firing approach for laser vaporisation of the human prostate–immediate efficacy and 1-year follow-up. Eur Urol 52:1717–1722

    Article  PubMed  Google Scholar 

  82. Servadio C (1992) Is open prostatectomy really obsolete? Urology 40:419–421

    Article  CAS  PubMed  Google Scholar 

  83. Shalev M, Richter S, Kessler O et al (1999) Long-term incidence of acute myocardial infarction after open and transurethral resection of the prostate for benign prostatic hyperplasia. J Urol 161:491–493

    Article  CAS  PubMed  Google Scholar 

  84. Sotelo R, Clavijo R, Carmona O et al (2008) Robotic simple prostatectomy. J Urol 179:513–515

    Article  PubMed  Google Scholar 

  85. Sotelo R, Spaliviero M, Garcia-Segui A et al (2005) Laparoscopic retropubic simple prostatectomy. J Urol 173:757–760

    Article  PubMed  Google Scholar 

  86. Sotelo RJ, Astigueta JC, Desai MM et al (2009) Laparoendoscopic single-site surgery simple prostatectomy: initial report. Urology 74:626–630

    Article  PubMed  Google Scholar 

  87. Spaliviero M, Araki M, Wong C (2008) Short-term outcomes of Greenlight HPS laser photoselective vaporization prostatectomy (PVP) for benign prostatic hyperplasia (BPH). J Endourol 22:2341–2347

    Article  PubMed  Google Scholar 

  88. Starkman JS, Santucci RA (2005) Comparison of bipolar transurethral resection of the prostate with standard transurethral prostatectomy: shorter stay, earlier catheter removal and fewer complications. BJU Int 95:69–71

    Article  PubMed  Google Scholar 

  89. Tan AH, Gilling PJ (2005) Lasers in the treatment of benign prostatic hyperplasia: an update. Curr Opin Urol 15:55–58

    Article  PubMed  Google Scholar 

  90. Tan AH, Gilling PJ, Kennett KM et al (2003) A randomized trial comparing holmium laser enucleation of the prostate with transurethral resection of the prostate for the treatment of bladder outlet obstruction secondary to benign prostatic hyperplasia in large glands (40 to 200 grams). J Urol 170:1270–1274

    Article  CAS  PubMed  Google Scholar 

  91. Te AE (2007) Is transurethral microwave thermotherapy comparable to transurethral resection for BPH? Nat Clin Pract Urol 4:478–479

    Article  PubMed  Google Scholar 

  92. Te AE, Malloy TR, Stein BS et al (2004) Photoselective vaporization of the prostate for the treatment of benign prostatic hyperplasia: 12-month results from the first United States multicenter prospective trial. J Urol 172:1404–1408

    Article  PubMed  Google Scholar 

  93. Tefekli A, Muslumanoglu AY, Baykal M et al (2005) A hybrid technique using bipolar energy in transurethral prostate surgery: a prospective, randomized comparison. J Urol 174:1339–1343

    Article  PubMed  Google Scholar 

  94. Thomas AW, Cannon A, Bartlett E et al (2005) The natural history of lower urinary tract dysfunction in men: minimum 10-year urodynamic followup of transurethral resection of prostate for bladder outlet obstruction. J Urol 174:1887–1891

    Article  PubMed  Google Scholar 

  95. Tkocz M, Prajsner A (2002) Comparison of long-term results of transurethral incision of the prostate with transurethral resection of the prostate, in patients with benign prostatic hypertrophy. Neurourol Urodyn 21:112–116

    Article  PubMed  Google Scholar 

  96. Tooher R, Sutherland P, Costello A et al (2004) A systematic review of holmium laser prostatectomy for benign prostatic hyperplasia. J Urol 171:1773–1781

    Article  PubMed  Google Scholar 

  97. Van Velthoven R, Peltier A, Laguna MP et al (2004) Laparoscopic extraperitoneal adenomectomy (Millin): pilot study on feasibility. Eur Urol 45:103–109; discussion 109

    Article  Google Scholar 

  98. Varkarakis I, Kyriakakis Z, Delis A et al (2004) Long-term results of open transvesical prostatectomy from a contemporary series of patients. Urology 64:306–310

    Article  PubMed  Google Scholar 

  99. Varkarakis J, Bartsch G, Horninger W (2004) Long-term morbidity and mortality of transurethral prostatectomy: a 10-year follow-up. Prostate 58:248–251

    Article  PubMed  Google Scholar 

  100. Vesely S, Knutson T, Dicuio M et al (2005) Transurethral microwave thermotherapy: clinical results after 11 years of use. J Endourol 19:730–733

    Article  PubMed  Google Scholar 

  101. Vogel A, Venugopalan P (2003) Pulsed ablation of biological tissues. Chem Rev 103

  102. Volkan T, Ihsan TA, Yilmaz O et al (2005) Short term outcomes of high power (80 W) potassium-titanyl-phosphate laser vaporization of the prostate. Eur Urol 48:608–613

    Article  PubMed  Google Scholar 

  103. Walmsley K, Kaplan SA (2004) Transurethral microwave thermotherapy for benign prostate hyperplasia: separating truth from marketing hype. J Urol 172:1249–1255

    Article  PubMed  Google Scholar 

  104. Wasson JH, Bubolz TA, Lu-Yao GL et al (2000) Transurethral resection of the prostate among medicare beneficiaries: 1984 to 1997. For the patient outcomes research team for prostatic diseases. J Urol 164:1212–1215

    Article  CAS  PubMed  Google Scholar 

  105. Xia SJ, Zhuo J, Sun XW et al (2008) Thulium laser versus standard transurethral resection of the prostate: a randomized prospective trial. Eur Urol 53:382–389

    Article  PubMed  Google Scholar 

  106. Yang Q, Peters TJ, Donovan JL et al (2001) Transurethral incision compared with transurethral resection of the prostate for bladder outlet obstruction: a systematic review and meta-analysis of randomized controlled trials. J Urol 165:1526–1532

    Article  CAS  PubMed  Google Scholar 

  107. Zargooshi J (2007) Open prostatectomy for benign prostate hyperplasia: short-term outcome in 3000 consecutive patients. Prostate Cancer Prostatic Dis 10:374–377

    Article  CAS  PubMed  Google Scholar 

  108. Zhou LY, Xiao J, Chen H et al (2009) Extraperitoneal laparoscopic adenomectomy for benign prostatic hyperplasia. World J Urol 27:385–387

    Article  PubMed  Google Scholar 

  109. Zlotta AR, Giannakopoulos X, Maehlum O et al (2003) Long-term evaluation of transurethral needle ablation of the prostate (TUNA) for treatment of symptomatic benign prostatic hyperplasia: clinical outcome up to five years from three centers. Eur Urol 44:89–93

    Article  PubMed  Google Scholar 

  110. Zwergel U, Wullich B, Lindenmeir U et al (1998) Long-term results following transurethral resection of the prostate. Eur Urol 33:476–480

    Article  CAS  PubMed  Google Scholar 

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  1. Urologische Klinik und Poliklinik, Klinikum Großhadern, Ludwig-Maximilians-Universität München, 81377, München, Deutschland

    O. Reich, M. Seitz, C. Gratzke, B. Schlenker, S. Walther & C. Stief

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Reich, O., Seitz, M., Gratzke, C. et al. Benignes Prostatasyndrom. Urologe 49, 113–126 (2010). https://doi.org/10.1007/s00120-009-2183-1

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