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Lasergestützte Resektionstechniken bei benigner Prostatahyperplasie

Laser-based resecting techniques in the treatment of benign prostatic obstruction

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Zusammenfassung

Für kaum eine Erkrankung in der Urologie gibt es so viele Therapieansätze wie für die Therapie der benignen Prostatahyperplasie (BPH). Über die letzten Jahrzehnte wurden immer wieder neue Therapieverfahren auf den Markt gebracht, um den Goldstandard, die monopolare Resektion mit der Schlinge, zu ersetzen. Nur wenige Verfahren haben sich hierbei klinisch tatsächlich etabliert. Nach einer ersten Verbreitungswelle des Nd:YAG-Lasers zur Behandlung der BPH wurde die Lasertherapie allerdings wieder komplett verlassen. Zu lang waren die Operationszeiten, zu mäßig die Erfolge und die Nebenwirkung zu ausgeprägt, um sich mit der TURP messen zu können.

Erst in den letzten Jahren hat, mit zunehmendem Verständnis der Laserphysik und der Entwicklung neuer Laser, die Laserchirurgie der benignen Prostataobstruktion wieder an Bedeutung gewonnen. Hierbei konkurrieren verschiedene vaporisierende und resezierende Verfahren um die Vormachtstellung in der klinischen Anwendung. Ziel dieses Artikels ist es, die aktuell zur Verfügung stehenden lasergestützten Resektionsverfahren vorzustellen und die Vor- sowie Nachteile der Verfahren zu beleuchten.

Abstract

A brought variety of options are at hand in the treatment of benign prostatic obstruction. During the last decades multiple therapeutic approaches have been pushed on the market to compete with the known Gold-Standard, the monopolar TUR-P. Only few have stood the test of time. The first wave of laser-based prostate surgery took place, when the Nd:YAG laser was introduced into clinical urology. However, operating time was long, surgical outcome often poor and the risk of serious complications was high. This lead to the vanishing of Nd:YAG lasers in clinical routine.

During the last years, with growing experience in laser physics and the development of new laser types, the laser-based prostatic surgery gained importance. In clinical routine different vaporizing or resecting techniques are established and compete on the market. Aim of this article is to review those lasers, which are currently used in resection techniques and to highlight advantages, but also disadvantages of the different systems.

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Literatur

  1. Bach T, Herrmann TR, Cellarius C, Gross AJ (2007) Bladder neck incision using a 70 W 2 micron continuous wave laser (RevoLix). World J Urol 25: 263–267

    Article  PubMed  Google Scholar 

  2. Bach T, Herrmann TR, Ganzer R et al. (2007) RevoLix vaporesection of the prostate: initial results of 54 patients with a 1-year follow-up. World J Urol 25: 257–262

    Article  PubMed  Google Scholar 

  3. Böwering R, Hofstetter A, Keiditsch E, Frank F (1979) Irradiation of prostatic carcinoma by neodymium-YAG-laser. Proc SPIE 211: 16–20

    Google Scholar 

  4. Camps JL Jr, Powers SK, Beckman WC Jr et al. (1985) Photodynamic therapy of prostate cancer: an in vitro study. J Urol 134: 1222–1226

    PubMed  Google Scholar 

  5. Elzayat E, Habib E, Elhilali M (2006) Holmium laser enucleation of the prostate in patients on anticoagulant therapy or with bleeding disorders. J Urol 175: 1428–1432

    Article  PubMed  CAS  Google Scholar 

  6. Elzayat EA, Elhilali MM (2006) Holmium laser enucleation of the prostate (HoLEP) the endourologic alternative to open prostatectomy. Eur Urol 49: 87–91

    Article  PubMed  Google Scholar 

  7. Elzayat EA, Elhilali MM (2007) Holmium laser enucleation of the prostate (HoLEP) long-term results, reoperation rate, and possible impact of the learning curve. Eur Urol 52: 1465–1471

    Article  PubMed  Google Scholar 

  8. Fried NM, Murray KE (2005) High-power thulium fiber laser ablation of urinary tissues at 1.94 microm. J Endourol 19: 25–31

    Article  PubMed  Google Scholar 

  9. Gilling PJ, Cass CB, Cresswell MD et al. (1996) The use of the holmium laser in the treatment of benign prostatic hyperplasia. J Endourol 10: 459–461

    PubMed  CAS  Google Scholar 

  10. Gilling PJ, Fraundorfer MR (1998) Holmium laser prostatectomy: a technique in evolution. Curr Opin Urol 8: 11–15

    Article  PubMed  CAS  Google Scholar 

  11. Gordon S, Watson G (2006) Thulium laser enucleation of the prostate. Eur Urol Suppl 5: 310

    Article  Google Scholar 

  12. Hochreiter WW, Thalmann GN, Burkhard FC, Studer UE (2002) Holmium laser enucleation of the prostate combined with electrocautery resection: the mushroom technique. J Urol 168: 1470–1474

    Article  PubMed  Google Scholar 

  13. Jansen ED, Leeuwen TG van, Motamedi M et al. (1994) Temperature dependence of the absorption coefficient of water for midinfrared laser radiation. Lasers Surg Med 14: 258–268

    Article  PubMed  CAS  Google Scholar 

  14. Johnson DE, Costello AJ, Wishnow KI (1991) Transurethral laser prostatectomy using a right angle laser delivery system. Lasers Surg Med Suppl 3: 76 S

    Google Scholar 

  15. Kabalin JN (1996) Holmium: YAG laser prostatectomy: results of U.S. pilot study. J Endourol 10: 453–457

    PubMed  CAS  Google Scholar 

  16. Kabalin JN, Mackey MJ, Cresswell MD et al. (1997) Holmium: YAG laser resection of prostate (HoLRP) for patients in urinary retention. J Endourol 11291–11293

  17. Kuntz RM (2007) Laser treatment of benign prostatic hyperplasia. World J Urol 25: 241–247

    Article  PubMed  Google Scholar 

  18. Kuntz RM, Ahyai S, Lehrich K, Fayad A (2004) Transurethral holmium laser enucleation of the prostate versus transurethral electrocautery resection of the prostate: a randomized prospective trial in 200 patients. J Urol 172: 1012–1016

    Article  PubMed  Google Scholar 

  19. Kuntz RM, Lehrich K, Ahyai SA (2008) Holmium laser enucleation of the prostate versus open prostatectomy for prostates greater than 100 grams: 5-year follow-up results of a randomised clinical trial. Eur Urol 53: 160–168

    Article  PubMed  Google Scholar 

  20. Matlaga BR, Miller NL, Lingeman JE (2007) Holmium laser treatment of benign prostatic hyperplasia: an update. Curr Opin Urol 17: 27–31

    Article  PubMed  Google Scholar 

  21. Matsuoka K, Iida S, Tomiyasu K et al. (1998) Holmium laser resection of the prostate. J Endourol 12: 279–282

    Article  PubMed  CAS  Google Scholar 

  22. McNichols TA, Pope AJ, Timoney A et al. (1992) Hyperthermia of the prostate by interstitial laser coagulation. J Urol 147: 345A

    Google Scholar 

  23. Meng F, Gao B, Fu Q et al. (2007) Change of sexual function in patients before and after Ho: YAG laser enucleation of the prostate. J Androl 28: 259–261

    Article  PubMed  Google Scholar 

  24. Moody JA, Lingeman JE (2001) Holmium laser enucleation for prostate adenoma greater than 100 gm.: comparison to open prostatectomy. J Urol 165: 459–462

    Article  PubMed  CAS  Google Scholar 

  25. Mulvany WP, Beck CW (1968) The laser beam in urology. J Urol 99: 112–115

    Google Scholar 

  26. Muschter R, Hessel S, Hofstetter A et al. (1993) Interstitielle Laserkoagulation der BPH Urologe A32: 273–281

  27. Naspro R, Freschi M, Salonia A et al. (2004) Holmium laser enucleation versus transurethral resection of the prostate. Are histological findings comparable? J Urol 171: 1203–1206

    Article  PubMed  Google Scholar 

  28. Parsons RL, Campbell JL, Thomley MW et al. (1966) The effect of the laser of dog bladders: a preliminary report. J Urol 95: 716–717

    PubMed  CAS  Google Scholar 

  29. Pedraza R, Samadi A, Eshghi M (2004) Holmium laser enucleation of the prostate in critically ill patients with technique modification. J Endourol 18: 795–798

    Article  PubMed  Google Scholar 

  30. Pierre SA, Albala DM (2007) The future of lasers in urology. World J Urol 25: 275–283

    Article  PubMed  Google Scholar 

  31. Roth RA, Aretz HAT, Lage AL (1990) „TULIP“: Transurethral laser induced prostatectomy under ultrasound guidance. J Urol 143: 285A

    Google Scholar 

  32. Seitz M, Sroka R, Gratzke C et al. (2007) The diode laser: a novel side-firing approach for laser vaporization of the human prostate – immediate efficacy and 1-year follow-up. Eur Urol 52(6): 1717–1722

    Article  PubMed  Google Scholar 

  33. Seki N, Mochida O, Kinukawa N et al. (2003) Holmium laser enucleation for prostatic adenoma: analysis of learning curve over the course of 70 consecutive cases. J Urol 170: 1847–1850

    Article  PubMed  Google Scholar 

  34. Staehler G, Halldorsson T, Langerholc J, Bilgram R (1981) Endoscopic application of the Nd: YAG laser in urology; theory, results, dosimetry. Urol Res 9: 45–51

    Article  PubMed  CAS  Google Scholar 

  35. Tan AH, Gilling PJ, Kennett KM et al. (2003) A randomized trial comparing holmium laser enucleation of the prostate with transurethral resection of the prostate for the treatment of bladder outlet obstruction secondary to benign prostatic hyperplasia in large glands (40 to 200 grams). J Urol 170: 1270–1274

    Article  PubMed  CAS  Google Scholar 

  36. Teichmann HO, Herrmann TR, Bach T (2007) Technical aspects of lasers in urology. World J Urol 25: 221–225

    Article  PubMed  Google Scholar 

  37. Wendt Nordahl G, Huckele S, Honeck P et al. (2007) Systematic evaluation of 2 µm thulium laser device for treatment of benign prostatic enlargement in an ex-vivo model. J Urol 177: S614

    Article  Google Scholar 

  38. Westenberg A, Gilling P, Kennett K et al. (2004) Holmium laser resection of the prostate versus transurethral resection of the prostate: results of a randomized trial with 4-year minimum long-term followup. J Urol 172: 616–619

    Article  PubMed  Google Scholar 

  39. Xia SJ, Zhuo J, Sun XW et al. (2008) Thulium laser versus standard transurethral resection oft he prostate: a randomized prospective trial. Eur Urol 53: 382–390

    Article  PubMed  Google Scholar 

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Gross, A., Bach, T. Lasergestützte Resektionstechniken bei benigner Prostatahyperplasie. Urologe 47, 455–460 (2008). https://doi.org/10.1007/s00120-008-1662-0

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