Zusammenfassung
Das Urothelkarzinom der Harnblase ist eine häufige Erkrankung, und in der Routinediagnostik wird regelmäßig die Urinzytologie angewendet. Dieses Verfahren weist jedoch bei hochdifferenzierten Tumoren nur eine geringe Sensitivität auf, und es ist als subjektives Verfahren sehr stark von der Erfahrung des Untersuchers abhängig. Wir stellen hier die Fluoreszenzzytologie als Weiterentwicklung der Urinzytologie vor, die das Potential hat, als automatisiertes Verfahren auf der Basis der 5-ALA-induzierten photodynamischen Diagnostik (PDD) diese Nachteile der Standardzytologie auszugleichen.
Abstract
Urothelial cancer of the bladder is a frequent disease, and urinary cytology often is used as a routine diagnostic tool. But this technique has an impaired sensitivity in low-grade tumours, and as a subjective method it is highly dependent on the experience of the cytologist. Here we present the technique of fluorescence cytology as an improvement of conventional cytology. This method is potentially able to compensate for the disadvantages of urinary cytology as it is an automated process that uses the principles of 5-Ala-induced photodynamic diagnosis (PDD).
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Tritschler, S., Tauber, S., Meier, R. et al. Die Fluoreszenzzytologie. Urologe 46, 1121–1123 (2007). https://doi.org/10.1007/s00120-007-1449-8
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DOI: https://doi.org/10.1007/s00120-007-1449-8