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Was gibt’s Neues beim Harnblasenkarzinom?

The latest news on bladder cancer

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Zusammenfassung

Eine Prüfung der aktuellen Literatur erbringt neue wissenschaftliche Erkenntnisse zur Diagnostik und Prognose und für neue molekulare Zielstrukturen. Die neue WHO-Klassifikation verfeinert unsere Stadieneinteilung und beeinflusst die Behandlungsoptionen des Blasenkarzinoms. Internationale klinische Daten zeigen neue Möglichkeiten, das individuelle Risiko bzgl. Remission oder Progression zu berechnen. Die systematische Genclusteranalyse definiert Multimarkerpanels, die als zuverlässige Prädikatoren für die Überlebenswahrscheinlichkeit dienen können. Die Entdeckung neuer Signalpfade beim Blasenkarzinom führen zu neuen Zielmolekülen für innovative Therapien.

Abstract

A review of the current literature provides new scientific insights into the diagnosis, prognosis and novel molecular targets for bladder cancer. The new WHO classification refines our staging system and influences treatment options. International clinical databases provide new tools for calculating the individual risk for bladder cancer recurrence and progression. Systematic gene cluster analysis defines multimarker panels that can serve as robust predictors of outcome. Discoveries of new signaling pathways in bladder cancer are leading to novel molecular targets for innovative therapies.

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Authors and Affiliations

  1. Urologische Klinik und Poliklinik der Technischen Universität München, Klinikum rechts der Isar, Ismaninger Str. 22, 81675, München, Deutschland

    M. Retz, R. Nawroth & J.E. Gschwend

  2. Urologische Belegabteilung, Städtisches Krankenhaus Kiel GmbH, Kiel, Deutschland

    J. Lehmann

Authors
  1. M. Retz
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  2. J. Lehmann
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  3. R. Nawroth
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  4. J.E. Gschwend
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Corresponding author

Correspondence to M. Retz.

Additional information

Präsentation im Rahmen des Schlussforums der Jahrestagung der Deutschen Gesellschaft für Urologie, Hamburg 2006

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Retz, M., Lehmann, J., Nawroth, R. et al. Was gibt’s Neues beim Harnblasenkarzinom?. Urologe 46, 727–732 (2007). https://doi.org/10.1007/s00120-007-1370-1

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  • DOI: https://doi.org/10.1007/s00120-007-1370-1

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