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Optionen der palliativen Therapie des Peniskarzinoms

Options in palliative therapy for penile cancer

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Zusammenfassung

Peniskarzinome gehören mit der Inzidenz von 0,1–0,9/100.000 Männer/Jahr zu den seltensten malignen Tumoren. Die meisten Patienten sind >50 Jahre. Der Tumor weist eine langsame Wachstumsrate auf. Der Erfolg der Therapie wird sehr stark durch den Lymphknotenstatus beeinflusst.

Der Tod am Krebs ist normalerweise Folge der lokalen Komplikationen, wie Arosionsblutung durch den Tumor oder infizierte Inguinalmetastasen. Die Therapie des fortgeschrittenen metastasierten Peniskarzinoms und der Komplikationen stellt eine Herausforderung dar. Unter Beachtung der Lebensqualität sollte die therapeutische Strategie das Alter des Patienten, sexuelle Funktion, Motivation und psychischen Zustand, die Vorerkrankungen und die Tumorbiologie berücksichtigen. Die palliative Therapie erfordert eine gute Zusammenarbeit mit Onkologen, Strahlentherapeuten, Plastischen Chirurgen, Physiotherapeuten und Psychologen.

Abstract

Penile cancer, with an incidence of 0.1–0.9/100,000 males/year, is one of the least common malignant tumors. Most patients are over 50 years old and the tumor is slow growing. Therapeutic success is highly dependent on lymph node status.

Cancer related death is usually due to local complications such as arrosion bleeding caused by the tumor or infected inguinal metastases. The therapy for advanced penile cancer and its complications represents a challenge. Taking into consideration quality of life, the therapeutic strategy should be based on the patient’s age, his sexual function, motivation and psychological condition, as well as previous illnesses and tumor biology. Palliative therapy requires good interdisciplinary work between oncologists, radiologists, plastic surgeons, physiotherapists and psychologists.

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  1. Urologische Klinik, Universitätsklinikum der RWTH, 52072, Pauwelsstraße 30, Aachen, Deutschland

    E. Preis & G. Jakse

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  1. E. Preis
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  2. G. Jakse
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Correspondence to E. Preis.

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Preis, E., Jakse, G. Optionen der palliativen Therapie des Peniskarzinoms. Urologe 46, 49–53 (2007). https://doi.org/10.1007/s00120-006-1273-6

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