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Urinzytologie und Urinmarker

Bedeutung für die Praxis

Urine cytology and urine markers

Significance for clinical practice

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Zusammenfassung

Das Urothelkarzinom der Harnblase ist eine häufige Erkrankung, die durch Screening von Risikogruppen rechtzeitig erkannt werden kann. Aufgrund der hohen Rezidivrate sind regelmäßige und engmaschige Nachsorgeuntersuchungen notwendig. Die Diagnose sowie die Kontrolle erfolgen über die Zystoskopie, die durch verschiedene, nichtinvasive Verfahren wie die Zytologie und Urinmarkersysteme ergänzt wird. Diese weisen gegenüber der Zystoskopie bezüglich ihrer Sensitivität und Spezifität unterschiedliche Vor- und Nachteile auf, sodass sie zusätzliche Informationen liefern können, die Zystoskopie jedoch nicht ersetzen. Dabei bleibt die klassische Urinzytologie das nichtinvasive Standardverfahren.

Abstract

Urothelial carcinoma of the bladder is a frequent disease that can be identified timely by screening patients at high risk. Due to the high rate of disease recurrence, frequent follow-up procedures are necessary. For this purpose, cystoscopy is the standard procedure, and supplementary non-invasive procedures such as cytology or tumor marker tests are used. These tests have different advantages and disadvantages in terms of their sensitivities and specificities. Thus, they provide additional information, but are not able to replace cystoscopy as the standard instrument in the diagnosis of bladder cancer.

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Tritschler, S., Zaak, D., Knuechel, R. et al. Urinzytologie und Urinmarker. Urologe 45, 1441–1448 (2006). https://doi.org/10.1007/s00120-006-1217-1

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  • DOI: https://doi.org/10.1007/s00120-006-1217-1

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