Skip to main content
SpringerLink
Log in

Tumor-induced dysfunction in T lymphocytes: increased sensitivity to apoptosis

  • Main topic
  • Published:
Der Urologe Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Finke JH, Rayman P, George R, Uzzo R, Tannenbaum CS, Kolenko V, Novick AC, Bukowski RM (2002) Tumor induced sensitivity to apoptosis in T cells from patients with renal cell carcinoma; role of NFxB suppression in this process. Clin Cancer Res 7:940–946

    Google Scholar 

  2. Kudo D, Rayman P, Horton C, Cathcart MK, Bukowski RM, Thornton M, Tannenbaum C, Finke JH (2003) Gangliosides expressed by the renal cell carcinoma cell line SK-RC-45 are involved in tumor-induced apoptosis of T cells. Cancer Res 63:1676–1683

    CAS  PubMed  Google Scholar 

  3. Molto L, Rayman P, Paszkiewicz-Kozik E, Thornton M, Reese L, Bukowski R, Finke J, Tannenbaum C (2003) The Bcl-2 transgene protects T cells from RCC-mediated apoptosis. Clin Cancer Res 9:4060–4068

    CAS  PubMed  Google Scholar 

  4. Tatsumi T, Kierstead LS, Ranieri E, Gesualdo L, Schena FP, Finke JH, Bukowski RM, Mueller-Berghalus J, Kirkwood JM, Kwok WW, Storkus WJ (2002) Disease-associated bias in T helper type 1 (Th1)/Th2 CD4+ T cell responses against MAGE-6 in HLA-DRB 1040 (+) patients with renal cell carcinoma and melanoma. J Exp Med 196:619–628

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Tatsumi T, Herrem CJ, Olson WC, Finke JH, Bukowski RM, Kinch MS, Ranieri E, Storkus WL (2003) Disease stage variation in CD4+ and CD8+ T-cell reactivity to the receptor tyrosine kinase EphA2 in patients with renal cell carcinoma. Cancer Res 63:4481–4489

    CAS  PubMed  Google Scholar 

  6. Ritter G, Livingston PO (1991) Ganglioside antigens expressed by human cancer cells. Semin Cancer Biol 2:401–409

    CAS  PubMed  Google Scholar 

Download references

Conflict of interest:

No information supplied

Author information

Authors and Affiliations

  1. Department of Immunology, Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, OH, USA

    J. H. Finke, C. Tannenbaum, P. Rayman, T. Das, K. Biswas, A. Richmond, C. Moon, M. Thornton, I. Gill & A. Novick

  2. The Glickman Urological Institute, The Cleveland Clinic Foundation, Cleveland, OH, USA

    J. H. Finke

  3. Department of Experimental Therapeutics, The Cleveland Clinic Foundation, Cleveland, OH, USA

    J. H. Finke & R. Bukowski

  4. University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA

    W. Storkus

  5. Bose Institute, Calcutta, India

    T. Das

  6. Department of Immunology, NB 30, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA

    J. H. Finke

Authors
  1. J. H. Finke
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. C. Tannenbaum
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. W. Storkus
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. P. Rayman
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. T. Das
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. K. Biswas
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. A. Richmond
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. C. Moon
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. M. Thornton
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. I. Gill
    View author publications

    You can also search for this author in PubMed Google Scholar

  11. A. Novick
    View author publications

    You can also search for this author in PubMed Google Scholar

  12. R. Bukowski
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to J. H. Finke.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Finke, J.H., Tannenbaum, C., Storkus, W. et al. Tumor-induced dysfunction in T lymphocytes: increased sensitivity to apoptosis. Urologe 43 (Suppl 3), 131–132 (2004). https://doi.org/10.1007/s00120-004-0600-z

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00120-004-0600-z

Keywords

Search

Navigation