Zusammenfassung
Das folgende Fallbeispiel beschreibt eine hämatogene Metastase in der Urethra eines Seminoms, welche zu einer obstruktiven Miktionssymptomatik mit der Notwendigkeit einer suprapubischen Zystostomie führte. Die daraufhin durchgeführte lokoregionale Radiotherapie führte sowohl zu einer kompletten Tumorremission mit Langzeitwirkung, als auch zu einem völligen Verschwinden der obstruktiven Miktionsproblematik.
Abstract
Anaplastic seminomas account for 5–10% of all seminomas. Their metastatic pattern is similar to the classic form of seminoma. We report on an oligophrenic patient with seminoma pT1 who developed a metastasis to the corpus spongiosum and penile urethra, which was successfully treated by local external radiotherapy resulting in long-term tumor remission over a 4-year follow-up period.
Literatur
Donohue JP, Zachary JM, Maynard BR (1982) Distribution of nodal metastases in nonseminomatous testis cancer. J Urol 128: 315
Bredael JJ, Vugrin D, Whitmore WF Jr (1982) Autopsy findings in 154 patients with germ cell tumors of the testis. Cancer 50: 548
Selikowitz SM, Olsson CA (1973) Metastatic urethral obstruction. Arch Surg 107: 908
Mostofi FK, Davis CJ Jr, Sesterhenn IA (1992) Carcinoma of the male and female urethra. Urol Clin North Am 19: 348
Marks LB, Shipley WU (1991) The role of radiation therapy in the treatment of testicular germ cell tumors. Hematol Oncol Clin North Am 5: 1172
Laguna MP, Pizzocaro G, Klepp O et al. (2001) EAU guidelines on testicular cancer. Eur Urol 40: 102
International Germ Cell Consensus Classification (1997) A prognostic factor-based staging system for metastatic germ cell cancers. International Germ Cell Cancer Collaborative Group. J Clin Oncol 15: 594
Frohlich MW, Small EJ (1998) Stage II nonseminomatous testis cancer: the roles of primary and adjuvant chemotherapy. Urol Clin North Am 25: 451
Saxman SB, Finch D, Gonin R et al. (1998) Long-term follow-up of a phase III study of three versus four cycles of bleomycin, etoposide, and cisplatin in favorable-prognosis germ cell tumors: the Indian University experience. J Clin Oncol 16: 702
De Wit R, Stoter G, Kaye SB et al. (1997) Importance of bleomycin in combination chemotherapy for good-prognosis testicular nonseminoma: a randomized study of the European Organization for Research and Treatment of Cancer Genitourinary Tract Cancer Cooperative Group. J Clin Oncol 15: 1837
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Gerber, R., Madersbacher, S., Fleischmann, A. et al. Seltene Seminommetastase im Corpus spongiosum und der Urethra. Urologe [A] 42, 1491–1492 (2003). https://doi.org/10.1007/s00120-003-0441-1
Issue Date:
DOI: https://doi.org/10.1007/s00120-003-0441-1