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Neue MRT-Leitlinien bei multipler Sklerose

New MRI guidelines for multiple sclerosis

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Zusammenfassung

Hintergrund

Die Leitlinien zum Einsatz der Magnetresonanztomographie (MRT) bei der Diagnose und Überwachung von multipler Sklerose (MS) wurden von einem Expertengremium überarbeitet, um einen effizienten Einsatz der MRT in der klinischen Routinepraxis zu bekommen.

Ziele

Die Leitlinien-Revision berücksichtigt nun neue Entwicklungen und relevante Wissensfortschritte, wie die anhaltende Diskussion um die Sicherheit in Bezug auf intravenöse gadoliniumbasierte Kontrastmittel. Der Wert der spinalen MRT für diagnostische, prognostische und Überwachungszwecke wurde neu evaluiert. Die Standardisierung zerebraler und spinaler MRT-Protokolle für Diagnostik, Einschätzung der Prognose und Therapiemonitoring sowie der Einsatz der 3‑D-FLAIR (Fluid-Attenuated Inversion Recovery) als wichtigste Sequenz für die zerebrale Diagnostik wurden eingeführt, da dies eine bessere Interpretation und Vergleichbarkeit, z. B. bei Verlaufsbeurteilungen, erlaubt.

Abstract

Background

To improve the efficient use of magnetic resonance imaging (MRI) in routine clinical practice, an expert panel has revised the guidelines for its use in the diagnosis and monitoring of multiple sclerosis (MS).

Objectives

The revised guidelines now take into account new developments and relevant advances in knowledge, such as the ongoing debate about safety related to intravenous gadolinium-based contrast agents. The value of spinal cord MRI for diagnostic, prognostic, and surveillance purposes has been re-evaluated. Standardization of brain and spinal cord MRI protocols for diagnosis, assessment of prognosis, and monitoring of therapy, as well as the use of 3D-FLAIR (three-dimensional fluid-attenuated inversion recovery) as the most important sequence in the diagnosis of lesions in the brain have been included, as this allows better interpretation and comparability, e.g., in follow-up assessments.

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Authors and Affiliations

  1. Klinik für Diagnostische und Interventionelle Neuroradiologie, Universitätsklinikum des Saarlandes, Kirrberger Straße, 66424, Homburg-Saar, Deutschland

    Wolfgang Reith, Alena Hausmann & Michael Kettner

Authors
  1. Wolfgang Reith
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  2. Alena Hausmann
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  3. Michael Kettner
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Correspondence to Wolfgang Reith.

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Interessenkonflikt

W. Reith, A. Hausmann und M. Kettner geben an, dass kein Interessenkonflikt besteht.

Für diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.

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Reith, W., Hausmann, A. & Kettner, M. Neue MRT-Leitlinien bei multipler Sklerose. Radiologe 62, 322–326 (2022). https://doi.org/10.1007/s00117-022-00991-y

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