Zusammenfassung
Klinisches/methodisches Problem
Evaluierung des gesunden bzw. pathologischen fetalen Gehirns.
Radiologische Standardverfahren
Die Magnetresonanztomographie.
Methodische Innovationen
Zukunftsweisende Techniken in der MRT-Bildgebung des fetalen Gehirns.
Leistungsfähigkeit
Die Diffusionstensorbildgebung (DTI) befindet sich bereits in der klinischen Anwendung, alle anderen Methoden sind bisher noch als experimentell zu werten.
Bewertung
Auf dem Weg zur Etablierung als Standardverfahren.
Empfehlung für die Praxis
Eine kombinierte Verarbeitung funktioneller und struktureller Daten, modelliert für jede Schwangerschaftswoche, wird es zukünftig ermöglichen, anhand dieser fusionierten Informationen einen präzisen Einblick in den Entwicklungsprozess des Gehirns zu erlangen. Diese Erkenntnisse und Ergebnisse werden entscheidend zur Klärung des zeitlichen Verlaufs und des komplexen Aufbaus früher morphologischer Auffälligkeiten beitragen sowie deren Einfluss auf kognitive und sensorische Fähigkeiten aufzeigen.
Abstract
Clinical/methodical issue
Evaluation of the normal and pathological fetal brain.
Standard radiological methods
Magnetic resonance imaging (MRI).
Methodical innovations
Advanced MRI of the fetal brain.
Performance
Diffusion tensor imaging (DTI) is used in clinical practice, all other methods are used at a research level.
Achievements
Serving as standard methods in the future.
Practical recommendations
Combined structural and functional data for all gestational ages will allow more specific insight into the developmental processes of the fetal brain. This gain of information will help provide a common understanding of complex spatial and temporal procedures of early morphological features and their impact on cognitive and sensory abilities.
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Schöpf, V., Dittrich, E., Berger-Kulemann, V. et al. Zukunftsweisende MRT-Techniken des fetalen Gehirns. Radiologe 53, 136–140 (2013). https://doi.org/10.1007/s00117-012-2401-5
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DOI: https://doi.org/10.1007/s00117-012-2401-5