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Nachweis und Charakterisierung von Lebermetastasen

Detection and characterization of liver metastases

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Zusammenfassung

Durch die Einführung von Ultraschallkontrastmitteln der zweiten Generation hat die Sonographie sowohl beim Nachweis von Lebermetastasen als auch bei ihrer Charakterisierung zu den anderen Schnittbildverfahren wie CT und MRT aufgeschlossen und kann dank ihrer hohen Zeit- und Ortsauflösung diesen gelegentlich überlegen sein. In zahlreichen Vergleichsstudien lagen ihre Sensitivität und Spezifität bei ca. 90%. Dank der hohen zeitlichen Auflösung ist die kontrastverstärkte Sonographie in der Lage, ein frühes und über nur wenige Sekunden anhaltendes arterielles Enhancement nachzuweisen. Aus strahlenhygienischer Sicht und bei fehlender Beeinträchtigung von Organfunktionen sollte die kontrastverstärkte Sonographie bei geeigneten Schallbedingungen als erstes bildgebendes Verfahren zur Evaluation einer hepatischen Metastasierung eingesetzt werden.

Abstract

Since the advent of second generation ultrasound (US) contrast agents, ultrasound has caught up with other imaging modalities for the detection and characterization of liver metastases and as a result of its high temporal and spatial resolution it can in some cases even be superior to computed tomography (CT) and magnetic resonance imaging (MRI). Many studies have demonstrated a sensitivity and specificity of over 90%. Due to its high temporal resolution contrast-enhanced US (CEUS) is capable of detecting even a very short duration of hyper-enhancement during the arterial phase. Radiation protection and lack of adverse effects on renal or thyroid function are additional arguments why CEUS should be recommended as the first imaging modality in the evaluation of hepatic metastases in cases of favorable scanning conditions.

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  1. Zentrale Sonographieabteilung, Klinikum Siloah, KRH, Roesebeckstr 15, 30559, Hannover, Deutschland

    H.-P. Weskott

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  1. H.-P. Weskott
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Correspondence to H.-P. Weskott.

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Weskott, HP. Nachweis und Charakterisierung von Lebermetastasen. Radiologe 51, 469–474 (2011). https://doi.org/10.1007/s00117-010-2100-z

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