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ZNS-Infektionen bei immunsupprimierten Patienten

CNS infections in immunocompromised patients

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Zusammenfassung

Erregerbedingte Entzündungen des ZNS sind beim immunkompetenten Patienten selten, unter Immunsuppression jedoch häufiger. Zusätzlich findet sich ein grundlegend verschiedenes Erregerspektrum. Pathognomonische Befunde in der Bildgebung existieren nicht, oftmals ist die Schnittbilddiagnostik auch bei ausgeprägter Klinik unauffällig oder unspezifisch. Der vorliegende Artikel soll einen Überblick über die häufigsten Erreger und bildmorphologischen Erscheinungsbilder geben. Auch die moderne Radiologie kann jedoch den Erregernachweis nicht ersetzen.

Abstract

CNS infections caused by infective agents are rare in immunocompetent hosts, but more frequent in immunocompromised patients. In addition, the spectrum of causative agents is completely different. There are no pathognomonic alterations in radiologic imaging, even in clinically severely ill patients imaging is often non-specific or inconspicious. This article gives a review of the most frequent infective agents and image alterations. Modern radiology is not yet able to replace the gold standard of pathogen detection.

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Authors and Affiliations

  1. Abt. für Diagnostische und Interventionelle Neuroradiologie,Radiologische Klinik, Universitätsklinikum des Saarlandes, 66421, Homburg/Saar, Deutschland

    K.M. Hartmann & W. Reith

  2. Universitätsklinikum des Saarlandes, Homburg/Saar, Deutschland

    M. Golinski

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  1. K.M. Hartmann
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  2. M. Golinski
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  3. W. Reith
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Correspondence to K.M. Hartmann.

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Hartmann, K., Golinski, M. & Reith, W. ZNS-Infektionen bei immunsupprimierten Patienten. Radiologe 48, 560–572 (2008). https://doi.org/10.1007/s00117-008-1680-3

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