Skip to main content
Log in

Differenzialdiagnose von Raumforderungen im Kleinhirnbrückenwinkel

Differential diagnosis of space demands in the cerebellopontine angle

  • Weiterbildung · Zertifizierte Fortbildung
  • Published:
Der Radiologe Aims and scope Submit manuscript

Zusammenfassung

Die Mehrzahl der Raumforderungen im Kleinhirnbrückenwinkel liegt extraaxial. Innerhalb der Kleinhirnbrückenwinkelzisterne verlaufen wichtige Strukturen, v. a. N. trigeminus, N. facialis, N. vestibulocochlearis sowie A. cerebelli inferior anterior, A. cerebelli inferior posterior und zum Sinus petrosus führende Venen. Die häufigsten Raumforderungen im Kleinhirnbrückenwinkel sind Akustikusneurinom, Meningeom sowie vaskuläre Ektasien und Aneurysmen. Seltener sind Epidermoid und andere Schwannome sowie Metastasen, Paragangliome und Arachnoidalzysten. Intraaxial gelegene Tumoren im Bereich des Kleinhirnbrückenwinkels sind v. a. Medulloblastom, Astrozytom und Ependymom, die vorwiegend bei Kindern vorkommen, seltener Plexuspapillome. Daneben finden sich Raumforderungen, die vom Felsenbein ausgehen, wie Cholesterolgranulom, maligne Otitis media, Paragangliome und Metastasen. Zur Differenzialdiagnose sind neben den anatomischen Strukturen auch die Kenntnisse der Darstellung der verschiedenen Raumforderungen und Tumoren im Kleinhirnbrückenwinkel notwendig.

Abstract

Most of the space demands in the cerebellopontine angle lie extra-axially. Important structures run within the cisterns of the cerebellopontine angle, such as the trigeminal, facial and vestibulocochlear nerves as well as the anterior inferior and posterior inferior cerebellar arteries and the veins which lead to the petrosal sinus. The most common space demands are caused by acoustic neuromas, meningeomas, vascular ectasia and aneurysms. Less common are epidermoid and other schwannomas as well as metastases, paragangliomas and arachnoidal cysts. Intra-axial tumours in the area of the cerebellopontine angle include the medulloblastoma, astrocytoma and the ependymoma, which occurs predominantly in children, in addition to the uncommon choroid plexus papilloma. Nearby, there are also space demands around the petrous bone, such as cholesterol granuloma, malignant otitis media, paraganglioma and metastases. For differential diagnosis, an understanding of the space requirements of the tumours in the cerebellopontine angle is needed in addition to knowledge of the anatomical structures.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1
Abb. 2
Abb. 3
Abb. 4
Abb. 5
Abb. 6
Abb. 7
Abb. 8
Abb. 9
Abb. 10
Abb. 11
Abb. 12
Abb. 13
Abb. 14
Abb. 15

Literatur

  1. Alobid I, Gaston F, Morello A, Menendez LM, Benitez P (2002) Cavernous haemangioma of the internal auditory canal. Acta Otolaryngol 122: 501–503

    Article  PubMed  Google Scholar 

  2. Barai S, Bandopadhayaya GP, Julka PK, Dhanapathi H, Haloi AK, Seith A (2004) Cerebellar medulloblastoma presenting with skeletal metastasis. J Postgrad Med 50: 110–112

    PubMed  Google Scholar 

  3. Barkovich AJ (2000) Pediatric neuroimaging. Lippincott, Williams & Wilkins, Philadelphia, p 400

  4. Baser ME, Makariou EV, Parry DM (2002) Predictors of vestibular schwannoma growth in patients with neurofibromatosis type 2. J Neurosurg 96: 217–222

    PubMed  Google Scholar 

  5. Behling E, Birbe R, Veznadaroglu E, Andrews DW, Flanders A, Ken LC (2004) Gliosarcoma arising from an anaplastic ependymoma: a case report of a rare entity. Hum Pathol 35: 512–516

    Article  PubMed  Google Scholar 

  6. Ben Ammar CN, Kochbati L, Frikha H et al. (2004) Primitive intracranial ependymomas. Salah-Azaiz institute experience. Cancer Radiother 8: 75–80

    PubMed  Google Scholar 

  7. Bonneville F, Sarrazin J-L, Marsot-Dupuch K et al. (2001) Unusual lesions of the cerebellopontine angle. A segmental approach. RadioGraphics 21: 419–438

    CAS  PubMed  Google Scholar 

  8. Brandsma D, Jansen GH, Spliet W, Van Nielen K, Taphoorn MJ (2003) The diagnostic difficulties of meningeal and intracerebral plasma cell granulomas — presentation of three cases. J Neurol 250: 1302–1306

    Article  PubMed  Google Scholar 

  9. Carvalho GA, Cervio A, Matthies C, Samii M (2000) Subarachnoid fat dissemination after resection of a cerebellopontine angle dysontogenic cyst: case report and review of the literature. Neurosurgery 47: 760–763

    Article  CAS  PubMed  Google Scholar 

  10. Chen CJ, Tseng YC, Hsu HL, Jung SM (2004) Imaging predictors of intracranial ependymoms. J Comput Assist Tomogr 28: 407–413

    Article  PubMed  Google Scholar 

  11. Choi JY, Chang KH, Yu IK et al. (2002) Intracranial and spinal ependymomas: review of MR images of 61 patients. Korean J Radiol 3: 219–228

    PubMed  Google Scholar 

  12. De Tella OI Jr, Herculano MA, Prandini MN, Stavile JN, Bonatelli AP (2003) Chordoid meningioma: report of two cases. Arq Neuropsiquiatr 61: 91–94

    PubMed  Google Scholar 

  13. Dutt SN, Mirza S, Chavda SV, Irving RM (2002) Radiologic differentiation of intracranial epidermoids from arachnoid cysts. Otol Neurotol 23: 84–92

    Article  PubMed  Google Scholar 

  14. Gerganov V, Bussarsky V, Romansky K, Popov R, Djendov S, Dimitri I (2003) Cerebellopontine angle meningiomas. Clinical features and surgical treatment. J Neurosurg Sci 47: 129–135

    CAS  PubMed  Google Scholar 

  15. Gomez-Brouchet A, Delisle MB, Cognard C et al. (2001) Vestibular schwannomas: correlations between magnetic resonance imaging and histopathologic appearance. Otol Neurotol 22: 79–86

    Article  CAS  PubMed  Google Scholar 

  16. Gwak HS, Hwang SK, Paek SH, Kim DG, Jung HW (2003) Long-term outcome of trigeminal neurinomas with modified classification focusing on petrous erosion. Surg Neurol 60: 39–48

    Article  PubMed  Google Scholar 

  17. Imhof H, Henk CB, Dirisamer A, Czerny C, Gstöttner W (2003) CT und MRT tumoröser Veränderungen des Schläfenbeins. Radiologe 43: 219–226

    Article  CAS  PubMed  Google Scholar 

  18. Inoue T, Kawahara N, Shibahara J, Masumoto T, Usami K, Kirino T (2004) Extradural neurenteric cyst of the cerebellopontine angle. Case report. J Neurosurg 100: 1091–1093

    PubMed  Google Scholar 

  19. KiMaio S, Mohr G, Dufour JJ, Albrecht S (2003) Distal mycotic aneurysm of the AICA mimicking intracanalicular acoustic neuroma. Can J Neurol Sci 30: 388–392

    PubMed  Google Scholar 

  20. Kwiek SJ, Bierzynska-Macyszyn G, Luszawski J et al. (2003) Correlation of facial nerve paresis and histopathological type vestibular schwannoma. Folia Neuropathol 41: 237–239

    PubMed  Google Scholar 

  21. Lunardi P, Missori P, Salvati M, Licastro G (1992) Cholesterol granuloma of the cerebello-pontine angle. Clin Neurol Neurosurg 94: 265–268

    Article  CAS  PubMed  Google Scholar 

  22. Mahmud MF, Khan AM, Nadol JB Jr (2003) Histopathology of the inner ear in unoperated acoustic neurinoma. Ann Otol Rhinol Laryngol 112: 979–986

    PubMed  Google Scholar 

  23. Mautner VF, Tatagiba M, Matthies C, Kluwe L (2003) Mosaikbildung bei Neurofibromatose Typ 2 und assoziiertes klinisches Spektrum. Aktuelle Neurologie 2003: 416

    Google Scholar 

  24. Mendenhall WM, Friedman WA, Amdur RJ, Antonelli PJ (2004) Management of acoustic schwannoma. Am J Otolaryngol 25: 38–47

    Article  PubMed  Google Scholar 

  25. Miyamoto RC, Miyamoto RT (2003) Pediatric neurotology. Semin Pediatr Neurol 10: 298–303

    PubMed  Google Scholar 

  26. Oruckaptan HH, Berker M, Soylemezoglu F, Ozcan OE (2001) Parafalcine chondrosarcoma: an unusual localization for a classical variant. Case report and review of the literature. Surg Neurol 55: 174–179

    Article  CAS  PubMed  Google Scholar 

  27. Osborn AG (2004) Diagnostic imaging. Brain. University of Utah School of Medicine, Salt Lake City, Utah

  28. Pilz P (1981) Herpes zoster oticus — neuropathologic contribution to the genesis of concomitant ficial paralysis. Wien Klin Wochenschr 25: 753–735

    Google Scholar 

  29. Reni M (2003) Guidelines for the treatment of adult intra-cranial grade II–III ependymal tumours. Forum (Genova) 13: 90–98

  30. Reni M, Brandes AA, Vavassori V et al. (2004) A multicenter study of the prognosis and treatment of adult brain ependymal tumors. Cancer 100: 1221–1229

    Article  PubMed  Google Scholar 

  31. Rodriguez F, Scheithauer BW, Ockner DM, Giannini C (2004) Solitary fibrous tumor of the cerebellopontine angle with salivary gland heterotopia: a unique presentation. Am J Surg Pathol 28: 139–142

    Article  PubMed  Google Scholar 

  32. Sarma S, Sekhar LN, Schessel DA (2002) Nonvestibular schwannomas of the brain: a 7-year experience. Neurosurgery 50: 437–449

    Article  PubMed  Google Scholar 

  33. Sathyanarayana S, Baskaya MK, Fowler M, Roberts R, Nanda A (2003) Solitary tuberculoma of the cerebellopontine angle: a rare presentation. J Clin Neurosci 10: 120–122

    Article  PubMed  Google Scholar 

  34. Schlote W, Riede U-N, Wiestler OD (2004) Nervensystem. In: Riede UN, Schaefer HE (Hrsg) Allgemeine und spezielle Pathologie. Thieme, Stuttgart New York

  35. Somers J, Faber LP (1999) Chondroma and Chondrosarcoma. Semin Thorac Cardiovasc Surg 11: 270–277

    CAS  PubMed  Google Scholar 

  36. Stipkovits EM, Graamans K, Jansen GH, Velthof MA (2001) Acoustic neuroma. Predominance of Antoni type B cells in tumors of patients with vestibular paresis. Otol Neurotol 22: 215–217

    Article  CAS  PubMed  Google Scholar 

  37. Tos M, Stangerup SE, Cayse-Thomasen P, Tos T, Thomsen J (2004) What is the real incidence of vestibular schwannoma? Arch Otolaryngol Head Neck Surg 130: 216–220

    Article  PubMed  Google Scholar 

  38. Warakaulle DR, Anslw P (2003) Differential diagnosis of intracranial lesions with high signal on T1 or low signal on T2-weighted MRI. Clin Radiol 12: 922–933

    Article  Google Scholar 

  39. Weber AL, Brown EW, Hug EB, Liebsch NJ (1995) Cartilaginous tumors and chordomas of the cranial base. Otolaryngol Clin North Am 28: 453–471

    CAS  PubMed  Google Scholar 

  40. Ymakawa H, Hattori T, Tanigawara T, Sahashi Y, Ohkuma A (2004) Intracanalicular aneurysm at the meatal loop of the distal anterior inferior cerebellar artery: a case report and review of the literature. Surg Neurol 61: 82–88

    Article  PubMed  Google Scholar 

  41. Yu KB, Lim MK, Kim HJ et al. (2002) Clear-cell meningioma: CT and MR imaging findings in two cases involving the spinal canal and cerebellopontine angle. Korean J Radiol 3: 125–129

    PubMed  Google Scholar 

Download references

Interessenkonflikt:

Der korrespondierende Autor versichert, dass keine Verbindungen mit einer Firma, deren Produkt in dem Artikel genannt ist, oder einer Firma, die ein Konkurrenzprodukt vertreibt, bestehen.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to W. Reith.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Holst, B., Grunwald, I.Q., Brill, G. et al. Differenzialdiagnose von Raumforderungen im Kleinhirnbrückenwinkel. Radiologe 44, 1113–1137 (2004). https://doi.org/10.1007/s00117-004-1131-8

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00117-004-1131-8

Schlüsselwörter

Keywords

Navigation