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Kombinierte Hybridsysteme (PET/CT, SPECT/CT) versus multimodale Bildgebung mit getrennten Systemen

Combined Scanners (PET/CT, SPECT/CT) Versus Multimodality Imaging with Separated Systems

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Zusammenfassung

Mit zunehmender Verbreitung von kombinierten PET/CT-Geräten hat die multimodale nuklearmedizinisch-radiologische Bildgebung in den letzten Jahren Einzug in die klinische Routine gefunden. Im Rahmen dieser Übersicht werden die notwendigen Komponenten für die multimodale Bildgebung, Strategien der Bildanalyse und Bildpräsentation sowie die diagnostischen Erwartungen an die kombinierte Diagnostik vorgestellt und diskutiert. Als zentraler Punkt wird die Frage abgehandelt, inwieweit kombinierte Geräte durch eine Softwarelösung auf der Basis getrennter Untersuchungen an getrennten Geräten ersetzt werden können. Die Vorteile und Limitationen der multimodalen Bildgebung mit kombinierten oder getrennten Geräten werden analysiert.

Abstract

With increasing use of combined PET/CT scanners in the last few years, multimodality imaging (Nuclear Medicine/Radiology) found its way into clinical routine diagnostics. In this overview, necessary components for multimodality imaging, strategies for image analysis and image presentation, and diagnostic goals of combined imaging are demonstrated and discussed. A special focus is on the question, whether combined scanners can be replaced by a software approach with separated modalities. Advantages and limitations of multimodality imaging with combined or separated scanners are shown.

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Literatur

  1. Alyafei S, Inoue T, Zhang H et al. (1999) Image fusion system using PACS for MRI, CT, and PET images. Clin Positron Imaging 2(3):137–143

    Article  PubMed  Google Scholar 

  2. Aquino SL, Asmuth JC, Alpert NM, Halpern EF, Fischman AJ (2003) Improved radiologic staging of lung cancer with 2-[18F]-fluoro-2-deoxy-D-glucose-positron emission tomography and computed tomography registration. J Comput Assist Tomogr 27(4):479–484

    Article  PubMed  Google Scholar 

  3. Cohade C, Wahl RL (2003) Applications of positron emission tomography/computed tomography image fusion in clinical positron emission tomography-clinical use, interpretation methods, diagnostic improvements. Semin Nucl Med 33(3):228–237

    PubMed  Google Scholar 

  4. Cohade C, Osman M, Marshall LN, Wahl RN (2003) PET-CT: accuracy of PET and CT spatial registration of lung lesions. Eur J Nucl Med Mol Imaging 30(5):721–726 (Epub 2003 Mar 1)

    PubMed  Google Scholar 

  5. Coleman RE, Hawk TC, Hamblen SM et al. (1999) Detection of recurrent brain tumor. Comparison of MR registered camera-based and dedicated PET images. Clin Positron Imaging 2(1):57–61

    Article  PubMed  Google Scholar 

  6. Dresel S, Grammerstorff J, Schwenzer K (2003) [18F]FDG imaging of head and neck tumours: comparison of hybrid PET and morphological methods. Eur J Nucl Med Mol Imaging 30(7):995–1003

    Article  CAS  PubMed  Google Scholar 

  7. Hutton BF, Braun M (2003) Software for image registration: algorithms, accuracy, efficacy. Semin Nucl Med 33(3):180–192

    Article  PubMed  Google Scholar 

  8. Keidar Z, Israel O, Krausz Y (2003) SPECT/CT in tumor imaging: technical aspects and clinical applications. Semin Nucl Med 33(3):205–218

    Article  PubMed  Google Scholar 

  9. Kinahan PE, Hasegawa BH, Beyer T (2003) X-ray-based attenuation correction for positron emission tomography/computed tomography scanners. Semin Nucl Med 33(3):166–179

    PubMed  Google Scholar 

  10. Maes F, Collignon A, Vandermeulen D, Marchal G, Suetens P (1997) Multimodality image registration by maximization of mutual information. IEEE Trans Med Imaging 16(2):187–198

    Article  CAS  PubMed  Google Scholar 

  11. Murphy M, O’Brien TJ, Morris K, Cook MJ (2001) Multimodality image-guided epilepsy surgery. J Clin Neurosci 8(6):534–538

    Article  CAS  PubMed  Google Scholar 

  12. Paulino AC, Thorstad WL, Fox T (2003) Role of fusion in radiotherapy treatment planning. Semin Nucl Med 33(3):238–243

    Article  PubMed  Google Scholar 

  13. Pelizzari CA, Chen GT, Spelbring DR, Weichselbaum RR, Chen CT (1989) Accurate three-dimensional registration of CT, PET, and/or MR images of the brain. J Comput Assist Tomogr 13(1):20–26

    CAS  PubMed  Google Scholar 

  14. Pfluger T, Schmied C, Porn U (2003) Integrated imaging using MRI and 123I metaiodobenzylguanidine scintigraphy to improve sensitivity and specificity in the diagnosis of pediatric neuroblastoma. Am J Roentgenol 181(4):1115–1124

    Google Scholar 

  15. Schoder H, Yeung HW (2004) Positron emission imaging of head and neck cancer, including thyroid carcinoma. Semin Nucl Med 34(3):180–197

    Article  PubMed  Google Scholar 

  16. Skalski J, Wahl RL, Meyer CR (2002) Comparison of mutual information-based warping accuracy for fusing body CT and PET by 2 methods: CT mapped onto PET emission scan versus CT mapped onto PET transmission scan. J Nucl Med 43(9):1184–1187

    PubMed  Google Scholar 

  17. Slomka PJ (2004) Software approach to merging molecular with anatomic information. J Nucl Med 45 (Suppl 1):36S–45S

    PubMed  Google Scholar 

  18. So EL (2002) Role of neuroimaging in the management of seizure disorders. Mayo Clin Proc 77(11):1251–1164

    PubMed  Google Scholar 

  19. Stokking R, Zubal IG, Viergever MA (2003) Display of fused images: methods, interpretation, and diagnostic improvements. Semin Nucl Med 33(3):219–227

    Article  PubMed  Google Scholar 

  20. Tsai CC, Tsai CS, Ng KK et al. (2003) The impact of image fusion in resolving discrepant findings between FDG-PET and MRI/CT in patients with gynaecological cancers. Eur J Nucl Med Mol Imaging 21:21

    Google Scholar 

  21. Visvikis D, Ell PJ (2003) Impact of technology on the utilisation of positron emission tomography in lymphoma: current and future perspectives. Eur J Nucl Med Mol Imaging 30(Suppl 1): S106–116

    PubMed  Google Scholar 

  22. Wells WM, 3rd, Viola P, Atsumi H, Nakajima S, Kikinis R (1996) Multi-modal volume registration by maximization of mutual information. Med Image Anal 1(1):35–51

    PubMed  Google Scholar 

  23. Winkler PA, Vollmar C, Krishnan KG, Pfluger T, Brückmann H, Noachtar S (2000) Usefulness of 3-D reconstructed images of the human cerebral cortex for localization of subdural electrodes in epilepsy surgery. Epilepsy Research 41(7):169–178

    Article  CAS  PubMed  Google Scholar 

  24. Zhang W, Simos PG, Ishibashi H et al. (2003) Multimodality neuroimaging evaluation improves the detection of subtle cortical dysplasia in seizure patients. Neurol Res 25(1):53–57

    Article  CAS  PubMed  Google Scholar 

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Pfluger, T., la Fougère, C., Stauss, J. et al. Kombinierte Hybridsysteme (PET/CT, SPECT/CT) versus multimodale Bildgebung mit getrennten Systemen. Radiologe 44, 1105–1112 (2004). https://doi.org/10.1007/s00117-004-1126-5

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