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Möglichkeiten der Ganzkörper-MRT zur Diagnostik muskuloskelettaler Erkrankungen

Possibilities of whole-body MRI for investigating musculoskeletal diseases

  • Ganzkörper-MRT
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Zusammenfassung

Dieser Beitrag gibt eine Übersicht über die Möglichkeiten und Limitationen der Ganzkörper-MRT für die Diagnostik von Erkrankungen des muskuloskelettalen Systems. Es werden die Vor- und Nachteile der Ganzkörper-MRT erörtert und ein Sequenzprotokoll für die muskuloskelettale Diagnostik vorgeschlagen. Auf Muskel-, Gelenk- und Knochenerkrankungen, bei denen der Einsatz der Ganzkörper-MRT indiziert erscheint, dabei insbesondere Polymyositis, Muskeldystrophie, rheumatoide Arthritis, Spondylitis ankylosans, Polytrauma, Skelettmetastasen, Plasmozytom und das maligne Lymphom wird eingegangen. Die Ganzkörper-MRT bietet neue Möglichkeiten, insbesondere zur Ausbreitungsdiagnostik und Verlaufskontrolle multifokaler muskuloskelettaler Erkrankungen. Der klinische Nutzen dieser Methode für die einzelnen Erkrankungsentitäten muss in weiteren Studien evaluiert werden.

Abstract

This contribution outlines possibilities and limitations of whole-body MRI for investigating musculoskeletal diseases. Benefits and drawbacks of the novel whole-body MRI technology are discussed and a possible whole-body MRI sequence protocol for musculoskeletal examinations is proposed. Muscle, joint and bone diseases are discussed in which the application of whole-body MRI may be of advantage. Particularly, polymyositis, muscledystrophy, rheumatoid arthritis, spondylitis ancylosans, multiple trauma, skeletal metastases, multiple myeloma and malignant lymphoma are mentioned. Whole-body MRI opens new advantages for the examination of multifocal musculoskeletal diseases. The clinical benefit of this method for particular diseases has to be evaluated in further studies, however.

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Literatur

  1. Engelhard K, Hollenbach HP, Wolfart K, v. Imhoff E, Fellner FA (2004) Comparison of whole-body MRI with automatic moving table technique and bone scintigraphy for screening for bone meatstases in patients with breast cancer. Eur Radiol 14(1):99–105

    Article  CAS  PubMed  Google Scholar 

  2. Lizuka-Mikami M, Nagai K, Yoshida K, Sugihara T, Suetsugu Y, Mikami M, Tamada T, Imai S, Kajihara Y, Fukunaga M (2004) Detection of bone marrow and extramedullary involvement on patients with non-Hodgkin’s lymphoma by whole-body MRI: comparison with bone and (67)Ga scintigraphics. Eur Radiol 14(6):1074–1081

    Article  PubMed  Google Scholar 

  3. Mazumdar A, Siegel MJ, Narra V, Luchtman-Jones L (2002) Whole body fast inversion recovery MR imaging of small cell neoplasms in pediatric patients: a pilot study. Am J Roentgenol 179(5):1261–1266

    Google Scholar 

  4. Green RA, Saifuddin A (2004) Whole spine MRI in the assessment of acute vertebral body trauma. Skeletal Radiol 33(3):129–135

    Google Scholar 

  5. Daldrup-Link HE, Franzius C, Link TM, Laukamp D, Sciuk J, Jurgens H, Schober O, Rummeny EJ (2001) Whole body MR imaging for detection of bone metastases in children and young adults: comparison with skeletal scintigraphy and FDG PET. Am J Roentgenol 177(1):229–236

    CAS  Google Scholar 

  6. O’Connell MJ, Powell T, Brennan D, Lynch T, Mc Carthy CJ, Eustace SJ (2002) Whole body MR imaging in the diagnosis of polymyositis. Am J Roentgenol 179(4):967–971

    Google Scholar 

  7. Walker RE, Eustace SJ (2001) Whole body magnetic resonance imaging: techniques, clinical indications, and future applications. Semin Musculoskelet Radiol 5(1):5–20

    Article  CAS  PubMed  Google Scholar 

  8. Abe T, Kojima K, Kearns CF, Yohena H, Fukuda J (2003) Whole body muscle hypertrophy from resistance training: distribution and total mass. Br J Sports Med 37(6):543–545

    Article  CAS  PubMed  Google Scholar 

  9. Gruning T, Tiepolt C, Kropp J, Franke WG (2001) Diagnosis of bone metastasis with whole body MRI? Radiologe 41(9):792–795

    Article  CAS  PubMed  Google Scholar 

  10. Tausig A, Mantey N, Berger F, Sommer H, Pluger T, Hahn K (2000) Advantages and limitations of whole-body bone marrow MRI using Turbo-STIR sequences in comparison to planar bone scans. Nuklearmedizin 39(6):174–179

    CAS  PubMed  Google Scholar 

  11. Hargarden G, O’Connell M, Kavanagh E, Powell T, Ward R, Eustace S (2003) Current concepts in whole-body imaging using turbo short tau inversion recovery MR imaging. Am J Roentgenol 180(1):247–252

    CAS  Google Scholar 

  12. Pichiecchio A, Uggetti C, Egitto MG, Berardinelli A, Orcesi S, Gorni KO, Zanardi C, Tagliabue A (2002) Quantitative MR evaluation of body compsition in patients with Duchenne muscular dystrophy. Eur Radiol 12(11):2704–2709

    PubMed  Google Scholar 

  13. Lauenstein TC, Goedhe SC, Herborn CU, Treder W, Ruehm SG, Debatin JF, Barkhausen J (2002) Three dimensional volumetric interpolated breath-hold MR imaging for whole-body tumor staging in less than 15 minutes: a feasibility study. Am J Roentgenol 179(2):445–449

    Google Scholar 

  14. Gong QY, Pheonix J, Kemp GJ, Garcia-Finana M, Frostick SP, Brodie DA, Edwards RH, Whitehouse GH, Roberts N (2000) Estimation of body composition in muscular dystrophy by MRI and stereology. J Magn Reson Imaging 12(3):467–475

    Article  CAS  PubMed  Google Scholar 

  15. Bohndorf K, Imhof H (1998) Radiologische Diagnostik der Knochen und Gelenke. Thieme, Stuttgart

  16. Steinborn M, Tilling R, Heuck A, Brügel M, Stäbler A, Reiser M (2000) Diagnostik der Metastasierung im Knochenmark mittels MRT. Radiologe 40:826–834

    Article  CAS  PubMed  Google Scholar 

  17. Baur A, Stabler A, Nagel D, Lamerz R, Bartl R, Hiller E, Wendtner C, Bachner F, Reiser M (2002) Magnetic resonance imaging as a supplement for the clinical staging system of Durie and Salmon? Cancer 95(6):1334–1345

    Article  PubMed  Google Scholar 

  18. Goehde S, Forsting M, Debatin J (2003) Screening with MRI. A new „all inclusive“ protocol. Semin Ultrasound CT MR 24:2–11

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Abteilung für Diagnostische Radiologie, Klinikum der Eberhardt-Karls-Universität Tübingen

    S. Lenk, C. D. Claussen & H. P. Schlemmer

  2. Abteilung für Strahlentherapie, Universitätsklinikum Tübingen

    S. Fischer

  3. Abteilung für Hämatoonkologie, Universitätsklinikum Tübingen

    I. Kötter

  4. Abteilung für Diagnostische Radiologie, Klinikum der Eberhardt-Karls-Universität, Hoppe-Seyler-Straße 3, 72076 , Tübingen

    S. Lenk

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  1. S. Lenk
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  2. S. Fischer
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  3. I. Kötter
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  4. C. D. Claussen
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  5. H. P. Schlemmer
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Correspondence to S. Lenk.

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Lenk, S., Fischer, S., Kötter, I. et al. Möglichkeiten der Ganzkörper-MRT zur Diagnostik muskuloskelettaler Erkrankungen. Radiologe 44, 844–853 (2004). https://doi.org/10.1007/s00117-004-1097-6

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  • DOI: https://doi.org/10.1007/s00117-004-1097-6

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