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Die chirurgische Therapie der Lungenmetastasen—Indikationen, Techniken und Ergebnisse

Surgical therapy of lung metastases—indications, technique, results

  • Perkutane Ablation von Lungenmetastasen
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Zusammenfassung

Für die chirurgische Therapie von Lungenmetastasen bestehen noch keine etablierten Leitlinien. Aus umfangreichen retrospektiven Patientenanalysen lassen sich jedoch Prognosefaktoren ableiten, die einer Therapieentscheidung zugrunde gelegt werden sollten. Das sind im Wesentlichen der ursprüngliche Primärtumor, die Dauer des krankheitsfreien Intervalls und die Anzahl der Lungenmetastasen. Oberstes chirurgisches Therapieziel ist die vollständige, aber möglichst parenchymsparende Tumorresektion. Die Fünfjahresüberlebensrate resezierter Patienten liegt unabhängig vom Primärtumor zwischen 35 und 48%. Umstritten ist nach wie vor, ob Lungenmetastasen über eine offene Thorakotomie oder unter videothorakoskopischen Bedingungen entfernt werden können. Unabhängig von der Verfahrenswahl sind thoraxchirurgische Eingriffe—auch im fortgeschrittenen Patientenalter—mit einer sehr geringen Morbidität und Mortalität durchführbar.

Abstract

Due to the absence of established guidelines for the surgical treatment of lung metastases, informational prognostic factors such as: initial primary tumor, length of disease-free interval and number of lung metastases, can be derived from extensive, retrospective patient analyses and thereby serve as a directive in the development of a therapeutic course of treatment. The ultimate surgical goal is a complete, yet, parenchymal-sparing tumor resection. Regardless of primary tumor type, the 5-year survival rate for resected patients varies between 26 and 53%. Controversy still remains as to whether lung metastases should be removed either via open thoracotomy, or under video thoracoscopic conditions. Independent of surgical approach, thoracic surgical operations are associated with very low rates of morbidity as well as mortality even in patients of advanced age.

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Stier, A., Heidecke, CD. Die chirurgische Therapie der Lungenmetastasen—Indikationen, Techniken und Ergebnisse. Radiologe 44, 715–718 (2004). https://doi.org/10.1007/s00117-004-1072-2

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