Autismusspektrumstörungen bei Erwachsenen mit Intelligenzminderung

Häufigkeiten und Charakteristika

Autism spectrum disorders in adults with intellectual disabilities

Frequencies and characteristics

Zusammenfassung

Hintergrund

Erfassung der Häufigkeiten und klinischen Charakteristika von Autismusspektrumstörungen (ASS) bei Personen mit Intelligenzminderung (IM).

Methoden

Querschnittliche Datenanalyse einer klinisch-psychiatrischen Stichprobe von 710 Menschen mit IM.

Ergebnisse

Die Häufigkeit von ASS in einer Stichprobe Erwachsener mit IM betrug 19 %. ASS war assoziiert mit einem höheren Schweregrad der IM, männlichem Geschlecht (bei leichter bis mittelgradiger IM), Behandlung mit Antikonvulsiva und einer selteneren Beschäftigung in Werkstätten.

Schlussfolgerungen

ASS ist eine häufige klinische Diagnose bei Erwachsenen mit IM.

Abstract

Objective

Collation of frequencies and clinical characteristics of autism spectrum disorders (ASD) in persons with intellectual disability (ID).

Methods

Cross-sectional analysis of a clinical psychiatric sample of 710 adults with ID and mental disorders.

Results

The frequency of ASD in an adult sample with ID was 19%. The occurrence of ASD was associated with a higher severity of ID, male gender (in mild to moderate ID), anticonvulsive therapy and reduced employment rates in workshops.

Conclusion

The ASD are a frequent clinical diagnosis in adults with ID.

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Danksagung

Julia Böhm dankt der Stiftung Irene sowie der Wissenschaftlichen Gesellschaft Autismus-Spektrum (WGAS) e. V. für die Unterstützung in Form eines Promotionsstipendiums.

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Correspondence to Julia Böhm.

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Interessenkonflikt

J. Böhm, A. Diefenbacher, M. Heinrich und T. Sappok geben an, dass kein Interessenkonflikt besteht.

Alle beschriebenen Untersuchungen am Menschen wurden mit Zustimmung der zuständigen Ethikkommission, im Einklang mit nationalem Recht sowie gemäß der Deklaration von Helsinki von 1975 (in der aktuellen, überarbeiteten Fassung) durchgeführt. Von allen beteiligten Patienten liegt eine Einverständniserklärung vor.

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Böhm, J., Diefenbacher, A., Heinrich, M. et al. Autismusspektrumstörungen bei Erwachsenen mit Intelligenzminderung. Nervenarzt 90, 490–496 (2019). https://doi.org/10.1007/s00115-018-0635-9

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Schlüsselwörter

  • Häufigkeiten
  • Intelligenzminderung
  • Autismusspektrumstörung
  • Psychiatrische Komorbiditäten
  • Medikation

Keywords

  • Frequencies
  • Intellectual disability
  • Autism spectrum disorder
  • Psychiatric comorbidities
  • Medication