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Neuropsychologische Defizite nach Kleinhirninfarkt

Neuropsychological dysfunction after cerebellar stroke

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Zusammenfassung

Ein 62-jähriger Patient wies als Folge eines rechtsseitigen ischämischen Kleinhirninfarktes (PICA-Stromgebiet) alltagsrelevante neuropsychologische Defizite auf. Diese umfassten schwerpunktmäßig Exekutivfunktionen und visuell-räumliche Gedächtnisleistungen; darüber hinaus bestanden affektive und Verhaltensauffälligkeiten sowie linguistische Besonderheiten. Anhand dieser Kasuistik wird die Literatur zu dem klinischen Bild des so genannten zerebellären kognitiv-affektiven Syndroms zusammenfassend dargestellt und kritisch diskutiert.

Summary

Secondary to an ischemic cerebellar lesion in the territory of the right posterior inferior cerebellar artery (PICA), a 62-year-old man suffered relevant neuropsychological dysfunction. This included disturbances of executive functions, impaired visuospatial memory, blunting of affect, inappropriate behaviour, and linguistic difficulties. In this case report, we discuss the clinical presentation of so-called cerebellar cognitive affective syndrome.

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Literatur

  1. Cabeza R, Nyberg L (2000) Imaging cognition II: an empirical review of 275 PET and fMRI studies. J Cogn Neurosci 12:1–47

    Article  CAS  Google Scholar 

  2. Fiez JA, Petersen SE, Cheney MK et al. (1992) Impaired non-motor learning and error detection associated with cerebellar damage. A single case study. Brain 115:155–178

    Google Scholar 

  3. Gebhart AL, Petersen SE, Thach WT (2002) Role of the posterolateral cerebellum in language. Ann NY Acad Sci 978:318–333

    Google Scholar 

  4. Glickstein M (2000) How are visual areas of the brain connected to motor areas for the sensory guidance of movement? Trends Neurosci 12:613–617

    Article  Google Scholar 

  5. Hoffmann M, Schmitt F (2004) Cognitive impairments in isolated subtentorial stroke. Acta Neurol Scand 109:14–24

    Article  Google Scholar 

  6. Holmes G (1939) The cerebellum of man. Brain 62:1–30

    Google Scholar 

  7. Ivry RB, Spencer RM, Zelaznik HN et al. (2002) The cerebellum and event timing. Ann NY Acad Sci 978:302–317

    Google Scholar 

  8. Malm J, Kristensen B, Karlsson T et al. (1998) Cognitive impairment in young adults with infratentorial infarcts. Neurology 51:433–440

    Google Scholar 

  9. Middleton FA, Strick PL (2001) Cerebellar projections to the prefrontal cortex of the primate. J Neurosci 21:700–712

    Google Scholar 

  10. Neau JP, Arroyo-Anllo E, Bonnaud V et al. (2000) Neuropsychological disturbances in cerebellar infarcts. Acta Neurol Scand 102:363–370

    Article  Google Scholar 

  11. Schmahmann JD, Sherman JC (1998) The cerebellar cognitive affective syndrome. Brain 121:561–579

    Article  PubMed  Google Scholar 

  12. Scott RB, Stoodley CJ, Anslow P et al. (2001) Lateralized cognitive deficits in children following cerebellar lesions. Dev Med Child Neurol 43:685–691

    Google Scholar 

  13. Seidler RD, Purushotham A, Kim SG et al. (2002) Cerebellum activation associated with performance change but not motor learning. Science 296:2043–2046

    Article  Google Scholar 

  14. Thach WT (1998) What is the role of the cerebellum in motor learning and cognition? Trends Cognit Sci 2:331–337

    Article  Google Scholar 

  15. Timmann, D, Maschke M, Kolb FP (2004) Motorische und kognitive Störungen bei zerebellären Erkrankungen. Aktuelle Neurol 31:170–179

    Article  Google Scholar 

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Correspondence to C. Willert.

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Willert, C., Schaumann-Kuchling, C., Adamaszek, M. et al. Neuropsychologische Defizite nach Kleinhirninfarkt. Nervenarzt 76, 988–991 (2005). https://doi.org/10.1007/s00115-004-1869-2

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  • DOI: https://doi.org/10.1007/s00115-004-1869-2

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