Horses and cows might teach us about human knees
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Our comparative study of the knees of horses and cows (paraphrased as highly evolved joggers and as domesticated couch-potatoes, respectively) demonstrates significant differences in the posterior sections of bovine and equine tibial cartilage, which are consistent with specialisation for gait. These insights were possible using a novel analytical measuring technique based on the shearing of small biopsy samples, called dynamic shear analysis. We assert that this technique could provide a powerful new tool to precisely quantify the pathology of osteoarthritis for the medical field.
KeywordsDynamic shear analysis Osteoarthritis Cartilage
We thank the United States Air Force Office of Scientific Research (FA9550-09-1-0111), Magdalen College Oxford, the European Research Council (SP2-GA-2008-233409), NIHR Biomedical Research Unit into Musculoskeletal Disease, Nuffield Orthopaedic Centre and University of Oxford for funding.
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