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Hirnstrukturelle Konsequenzen perinataler Stress- und Deprivationserfahrungen

Effects of perinatal stress and deprivation on functional brain development

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Zusammenfassung

Der Artikel fasst die Bedeutung frühkindlicher Erfahrungen für die funktionelle Reifung des Gehirns und die Entwicklung geistiger und psychischer Fähigkeiten aus neurobiologischer Sicht zusammen. Es wird dargelegt, dass vor allem emotionale Erfahrungen einen synaptischen Selektions- und Reorganisationsprozess in den präfrontalen kortikalen und subkortikalen Regionen des limbischen Systems auslösen und somit die funktionelle Optimierung dieses „Belohnungssystems“ maßgeblich steuern, welches bei Lern- und Gedächtnisprozessen eine essenzielle Rolle spielt.

Abstract

The article summarizes the critical importance of perinatal emotional experience on functional brain maturation and the development of intellectual and emotional behaviors from a neurobiologic standpoint. Emphasis is given to the effect of early emotional experience, which triggers neuronal and synaptic selection and reorganization processes in prefrontal cortical and subcortical limbic pathways and thereby optimizes the functional capacity of these “emotional” systems which play an essential role in learning and memory formation and retrieval.

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  1. Abteilung Zoologie und Entwicklungsneurobiologie, Institut für Biologie, Otto-von-Guericke-Universität Magdeburg, Leipzigerstraße 44, 39120, Magdeburg, Deutschland

    A.K. Braun

  2. Arbeitsgruppe „Funktionelle Plastizität“, Institut für Biologie, Otto-von-Guericke-Universität Magdeburg, Magdeburg, Deutschland

    J. Bock

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  1. A.K. Braun
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Correspondence to A.K. Braun.

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Braun, A., Bock, J. Hirnstrukturelle Konsequenzen perinataler Stress- und Deprivationserfahrungen. Monatsschr Kinderheilkd 156, 629–634 (2008). https://doi.org/10.1007/s00112-008-1783-y

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  • DOI: https://doi.org/10.1007/s00112-008-1783-y

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