References
Nadal-Ginard B, Mahdavi V (1989) Molecular basis of cardiac performance. J Clin Invest 84:1693–1700
Alpert NR, Mulieri LA (1982) Increased myothermal economy of isometric force generation in compensated cardiac hypertrophy induced by pulmonary artery constriction in rabbit. Circ Res 50:491–500
Ritter O, Luther HP, Haase H, Baltas LG, Balzereit D, Baumann G, Schulte HD, Morano I (1999) Expression of atrial myosin light chains but not a-myosin heavy chains correlate with increased ventricular function in patients with HOCM in vivo. J Mol Med DOI 10.1007/s001099900030
Morano I, Haase H (1997) Different actin affinities of human cardiac essential myosin light chain isoforms. FEBS Lett 408:71–74
Morano I, Ritter O, Bonz A, Timek T, Vahl CF, Michel G (1995) Myosin light chain–actin interaction regulates cardiac contractility. Circ Res 76:720–725
Morano M, Zacharzowski U, Maier M, Lange PE, Alexi-Meskishvili V, Haase H, Morano I (1996) Regulation of human heart contractility by essential myosin light chain isoforms. J Clin Invest 98:467–473
Morano I, Hädicke K, Haase H, Böhm M, Erdmann E, Schaub MC (1996) Changes in essential myosin light chain isoform expression provide a molecular basis for isometric force regulation in the failing human heart. J Mol Cell Cardiol 29:1177–1187
Fewell JG, Hetwett TE, Sanbe A, Klevitsky R, Hayes E, Warshaw D, Maughan D, Robbins J (1998) Functional significance of cardiac myosin essential light chain isoform switching in transgenic mice. J Clin Invest 101:2630–2639
Whittaker M, Wilson-Kubalek EM, Smith JE, Faust L, Milligan RA, Sweeney HL (1995) A 35-A movement of smooth muscle myosin and ADP release. Nature 378:748–751
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Kops, G., Luft, F. A light, rather than a heavy solution for hard working hearts. J Mol Med 77, 631–633 (1999). https://doi.org/10.1007/s001099900037
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DOI: https://doi.org/10.1007/s001099900037