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Journal of Molecular Medicine

, Volume 94, Issue 9, pp 971–977 | Cite as

Archaeogenetics in evolutionary medicine

  • Abigail Bouwman
  • Frank Rühli
Review

Abstract

Archaeogenetics is the study of exploration of ancient DNA (aDNA) of more than 70 years old. It is an important part of the wider studies of many different areas of our past, including animal, plant and pathogen evolution and domestication events. Hereby, we address specifically the impact of research in archaeogenetics in the broader field of evolutionary medicine. Studies on ancient hominid genomes help to understand even modern health patterns. Human genetic microevolution, e.g. related to abilities of post-weaning milk consumption, and specifically genetic adaptation in disease susceptibility, e.g. towards malaria and other infectious diseases, are of the upmost importance in contributions of archeogenetics on the evolutionary understanding of human health and disease. With the increase in both the understanding of modern medical genetics and the ability to deep sequence ancient genetic information, the field of archaeogenetic evolutionary medicine is blossoming.

Keywords

Evolution of health Pathogen Immunity Adaptive changes 

Notes

Compliance with ethical standards

Authorship statement

AB and FR designed the article.

AB with some help of FR wrote the article.

AB and FR finalized and approved the article.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  1. 1.Universitat ZurichZürichSwitzerland

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