Skip to main content
SpringerLink
Log in

What we learned from narcolepsy of others

  • Clinical Implications
  • Published:
Journal of Molecular Medicine Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1.

References

  1. Mitler MM, Hajdukovic R, Erman M, Koziol JA (1990) Narcolepsy. J Clin Neurophysiol 7:93–118

    CAS  PubMed  Google Scholar 

  2. Gencik M, Dahmen N, Wieczorek S, Kasten M, Bierbrauer J, Anghelescu I, Szegedi A, Menezes Saecker AM, Epplen JT (2001) A prepro-orexin gene polymorphism is associated with narcolepsy. Neurology 56:115–117

    CAS  PubMed  Google Scholar 

  3. Mignot E, Hayduk R, Black J, Grumet FC, Guilleminault C (1997) HLA DQB1*0602 is associated with cataplexy in 509 narcoleptic patients. Sleep 20:1012–1020

    CAS  PubMed  Google Scholar 

  4. Mignot E, Young T, Lin L, Finn L (1999) Nocturnal sleep and daytime sleepiness in normal subjects with HLA-DQB1*0602. Sleep 22:347–352

    CAS  PubMed  Google Scholar 

  5. Wieczorek S, Dahmen N, Jagiello P, Epplen JT, Gencik M (2003) Polymorphisms of the TNF-receptors: no association with narcolepsy in German patients. J Mol Med (http://dx.doi.org/10.1007/s00109–002–0405–8)

  6. Lin L, Faraco J, Li R, Kadotani H, Rogers W, Lin X, Qiu X, de Jong PJ, Nishino S, Mignot E (1999) The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene. Cell 98:365–376

    CAS  PubMed  Google Scholar 

  7. Chemelli RM, Willie JT, Sinton CM, Elmquist JK, Scammell T, Lee C, Richardson JA, Williams SC, Xiong Y, Kisanuki Y, Fitch TE, Nakazato M, Hammer RE, Saper CB, Yanagisawa M (1999) Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell 98:437–451

    CAS  PubMed  Google Scholar 

  8. Willie JT, Chemelli RM, Sinton CM, Yanagisawa M. To eat or to sleep? Orexin in the regulation of feeding and wakefulness (2001) Annu Rev Neurosci 24:429–458

    Google Scholar 

  9. Mieda M, Yanagisawa M. Sleep, feeding, and neuropeptides: roles of orexins and orexin receptors (2002) Curr Opin Neurobiol 12:339–345

    Google Scholar 

  10. Beuckmann C, Yanagisawa M (2002). Orexins: from neuropeptides to energy homeostasis and sleep/wake regulation. J Mol Med 80:329–342

    CAS  PubMed  Google Scholar 

  11. Nishino S, Ripley B, Overeem S, Lammers GJ, Mignot E (2000) Hypocretin (orexin) deficiency in human narcolepsy. Lancet 355:39–40

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Franz-Volhard-Klinik, Humboldt University of Berlin, Wiltbergstrasse 50, 13125, Berlin-Buch, Germany

    Friedrich C. Luft

Authors
  1. Friedrich C. Luft
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Friedrich C. Luft.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Luft, F.C. What we learned from narcolepsy of others. J Mol Med 81, 69–70 (2003). https://doi.org/10.1007/s00109-002-0408-5

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00109-002-0408-5

Search

Navigation