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Obeticholsäure bei primär biliärer Cholangitis

PBC OCA International Study of Efficacy (POISE)

Obeticholic acid in primary biliary cholangitis

PBC OCA international study of efficacy (POISE)

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Literatur

  1. Yimam KK, Bowlus CL (2014) Obeticholic acid for the treatment of primary biliary cirrhosis. Expert Opin Orphan Drugs 2:1351–1358

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  2. Trivedi PJ, Hirschfield GM, Gershwin ME (2015) Obeticholic acid for the treatment of primary biliary cirrhosis. Expert Ref Clin Pharmacol 9:1–14

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  3. Nevens F et al for the POISE Study Group (2016) A placebo-controlled trial of obeticholic acid in primary biliary chonangitis. New Engl J Med 375:631−643

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Author information

Authors and Affiliations

  1. Klinik für Gastroenterologie und Hepatologie, Universitätsklinikum Essen, Hufelandstr. 55, 45122, Essen, Deutschland

    G. Gerken

  2. Lippetal, Deutschland

    S. Nitschmann

Authors
  1. G. Gerken
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  2. S. Nitschmann
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Corresponding author

Correspondence to G. Gerken.

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Interessenkonflikt

G. Gerken gibt an, von folgenden Unternehmen Vortragshonorare erhalten zu haben: AbbVie, BMS, Falk Foundation, Gilead, Intercept, Janssen-Cilag, MSD. S. Nitschmann gibt an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren.

Additional information

Redaktion

M. Hallek, Köln

W. Lehmacher, Köln

N. Marx, Aachen

U. Müller-Ladner, Bad Nauheim

H. Wedemeyer, Hannover

M. Wehling, Mannheim

T.R. Weihrauch, Düsseldorf

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Gerken, G., Nitschmann, S. Obeticholsäure bei primär biliärer Cholangitis. Internist 58, 202–204 (2017). https://doi.org/10.1007/s00108-016-0185-9

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  • DOI: https://doi.org/10.1007/s00108-016-0185-9

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