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Benigne rekurrierende aseptische Meningitis

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Benign recurring aseptic meningitis

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Zusammenfassung

Die benigne rekurrierende aseptische Meningitis (BRAM) oder Mollaret-Meningitis ist ein seltenes Krankheitsbild charakterisiert durch wiederholte Episoden einer aseptischen Meningitis gefolgt von beschwerdefreien Intervallen. Die Krankheit kann einen mehrjährigen Verlauf nehmen. Die Erkrankung wird häufig durch HSV-2 verursacht, seltener durch andere Viren oder Autoimmunerkrankungen. In bis zu 10 % bleibt die Genese unklar. Wir schildern den Fall einer Patientin mit idiopathischer BRAM und diskutieren anhand der Symptomatik, Diagnosestellung sowie anhand möglicher Therapien dieses seltene Krankheitsbild.

Abstract

Benign recurrent aseptic meningitis (BRAM) or Mollaret’s meningitis is a rare disease characterized by recurrent episodes of aseptic meningitis followed by spontaneous recovery. Disease courses over several years have been reported. In most cases, BRAM is caused by HSV-2, less frequently by other viruses or autoimmune diseases. In up to 10 %, the aetiology remains unclear. We present a case of idiopathic BRAM and discuss clinical findings, diagnosis and therapeutic options of this rare illness.

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Authors and Affiliations

  1. Medizinische Klinik mit Schwerpunkt Gastroenterologie, Infektiologie und Rheumatologie, Charité – Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Deutschland

    T. Kruis, L. Kredel, M. Nassir & T. Schneider

  2. Medizinische Universität Wien, Wien, Österreich

    M. Godbersen

Authors
  1. T. Kruis
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  2. L. Kredel
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  3. M. Nassir
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  4. M. Godbersen
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  5. T. Schneider
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Corresponding author

Correspondence to T. Kruis.

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Interessenkonflikt

T. Kruis, L. Kredel, M. Nassir, M. Godbersen und T. Schneider geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.

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Redaktion

H. Haller, Hannover (Schriftleitung)

B. Salzberger, Regensburg

C. Sieber, Nürnberg

T. Kruis und L. Kredel teilen sich die Erstautorenschaft.

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Kruis, T., Kredel, L., Nassir, M. et al. Benigne rekurrierende aseptische Meningitis . Internist 57, 188–193 (2016). https://doi.org/10.1007/s00108-015-0003-9

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  • DOI: https://doi.org/10.1007/s00108-015-0003-9

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