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Tumorbedingte Fatigue und ihre psychosozialen Belastungen

Cancer-related fatigue and its psychosocial burden

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Zusammenfassung

Die tumorbedingte Fatigue ist ein verbreitetes und sehr belastendes Syndrom im Rahmen der Krebserkrankung und -therapie. Tumorbedingte Fatigue geht mit dem subjektiven Gefühl von physischer und mentaler Müdigkeit, Erschöpfung, Energieverlust und eingeschränkten Möglichkeiten der Erholung einher. Zum Diagnosezeitpunkt klagen bis zu 40%, im weiteren Verlauf der Krebsbehandlung mehr als 90% der Patienten über tumorbedingte Fatigue. Die psychosozialen Beeinträchtigungen sind erheblich; die Lebensqualität, das psychische Wohlbefinden, die Teilhabe am Alltagsleben und die berufliche Leistungsfähigkeit sind meist erheblich eingeschränkt. Die Ätiologie der Fatigue, insbesondere die Rolle psychosozialer Faktoren wie „distress“, Depression oder Angst, ist bislang noch nicht hinreichend erforscht. Die vorliegende Arbeit gibt einen Überblick über epidemiologische Grundlagen, krankheitsbegleitende Aspekte und psychosoziale Belastungen bei tumorbedingter Fatigue.

Abstract

Cancer-related fatigue (CRF) is a highly prevalent and the most distressing symptom during and after treatment for cancer. It is characterized by feelings of physical and mental tiredness, weakness, and lack of energy and is not influenced by rest or sleep. Approximately 40% of patients suffer from CRF at diagnosis and nearly all patients experience fatigue during the course of cancer therapy. The impact of CRF on daily living and patient quality of life (QoL) is substantial. It profoundly affects patient quality of life and limits personal, social and occupational roles. The fatigue is also associated with significant levels of distress and it imposes a financial burden by limiting the ability to work. The underlying causes of CRF are poorly understood as are the relationship between fatigue and psychosocial distress, depression or anxiety. This paper seeks to give an overview of cancer-related fatigue and its psychosocial burden.

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Authors and Affiliations

  1. Zentrum für Klinische Psychologie und Rehabilitation, Universität Bremen, Grazer Str. 6, 28359, Bremen, Deutschland

    U. de Vries & F. Petermann

  2. Institut für Public Health und Pflegeforschung, Abt. Interdisziplinäre Alterns- und Pflegeforschung, Universität Bremen, Bremen, Deutschland

    K. Reif

Authors
  1. U. de Vries
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  2. K. Reif
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  3. F. Petermann
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Correspondence to U. de Vries.

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de Vries, U., Reif, K. & Petermann, F. Tumorbedingte Fatigue und ihre psychosozialen Belastungen. Internist 52, 1317–1324 (2011). https://doi.org/10.1007/s00108-011-2921-5

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