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Multiple Raumforderungen bei einem 30-Jährigen mit Stuhlinkontinenz

30 year-old patient with multiple pelvic lesions and fecal incontinence

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Zusammenfassung

Bei einem 30-jährigen Patienten mit subakuter Stuhlinkontinenz und perianalem Sensibilitätsverlust zeigten sich in der Bildgebung multiple pelvine knöcherne Läsionen. In der Knochenmarkbiopsie erfolgte daraufhin der Nachweis einer akuten myeloischen Leukämie M2 mit Translokation t(8,21), die sich bildgebend in Form multipler Chlorome und hinsichtlich des Blutbilds aleukämisch erstmanifestierte. Unter Hochdosischemotherapie und autologer Stammzelltranplantation blieb der Patient in anhaltender Remission.

Abstract

In a 30 year-old patient with subacute loss of bowel control and perianal anesthesia radiologic examination showed multiple bone lesions. The results of a bone marrow aspiration showed acute myeloid leukemia M2 with translocation t(8,21) associated with granulocytic sarcoma. The patient was treated with high dose chemotherapy and had a complete remission after autologous stem cell transplantation.

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Authors and Affiliations

  1. Medizinische Klinik A, Klinikum Ludwigshafen, Bremserstraße 79, 67063, Ludwigshafen, Deutschland

    J. Schanz, B. Weiss, D. Henrich & M. Uppenkamp

  2. Institut für Pathologie, Klinikum Ludwigshafen, Ludwigshafen, Deutschland

    M.H. Bohrer

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  1. J. Schanz
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  2. B. Weiss
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  3. D. Henrich
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  4. M.H. Bohrer
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  5. M. Uppenkamp
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Correspondence to J. Schanz.

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Schanz, J., Weiss, B., Henrich, D. et al. Multiple Raumforderungen bei einem 30-Jährigen mit Stuhlinkontinenz. Internist 50, 1155–1160 (2009). https://doi.org/10.1007/s00108-009-2342-x

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  • DOI: https://doi.org/10.1007/s00108-009-2342-x

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