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Klinik und Diagnostik der Osteoporose und Osteomalazie

Clinical presentation and diagnosis of osteoporosis and osteomalacia

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Zusammenfassung

Osteoporose und Osteomalazie sind systemische metabolische Knochenerkrankungen, welche die Zusammensetzung, Architektur und Funktion des Knochens beeinträchtigen. Aufgrund der demografischen Entwicklung und sensitiver Nachweisverfahren werden beide Erkrankungen zunehmend häufiger diagnostiziert. Insbesondere ältere und chronisch kranke Menschen oder Bewohner in Seniorenresidenzen sind betroffen. Patienten mit gastroenterologischen, rheumatologischen und endokrinologischen Grunderkrankungen weisen ebenfalls ein hohes Risiko einer Osteoporose oder Osteomalazie auf. In dieser aktuellen Übersicht werden die praktischen Aspekte zur Klinik und Diagnostik der Osteoporose und der Osteomalazie dargestellt.

Abstract

Osteoporosis and osteomalacia are systemic metabolic bone diseases characterized by an impaired composition, architecture, and quality of bone. In light of the demographic development and the recent use of sensitive tests, both diseases are increasingly diagnosed. Subjects at high risk include elderly, chronically hospitalized patients, and nursing home residents. Patients with gastrointestinal, rheumatologic and endocrine disorders are also at risk for the development of osteoporosis or osteomalacia. In this review, we will discuss practical aspects of the clinical presentation and the diagnosis of osteoporosis and osteomalacia.

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Correspondence to L.C. Hofbauer.

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Därr, R., Ziller, V., Hadji, P. et al. Klinik und Diagnostik der Osteoporose und Osteomalazie. Internist 49, 1170–1177 (2008). https://doi.org/10.1007/s00108-008-2114-z

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