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Adjuvante Chemotherapie bei soliden Tumoren des Gastrointestinaltrakts

Sind Fortschritte zu erkennen?

Adjuvant chemotherapy of solid tumors of the gastrointestinal tract: Where is the progress?

  • Schwerpunkt: Was ist gesichert in der Therapie?
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Zusammenfassung

Eine chirurgische Therapie strebt die vollständige Entfernung eines Tumors aus dem Organismus an. Eine anschließende adjuvante Chemotherapie soll durch die Beseitigung verbliebener Tumorzellen das Rezidiv verhindern und damit die langfristige Heilung verbessern. In den letzten Jahren konnte durch multimodale Konzepte, unter Einbeziehung neuer Kombinationschemotherapieschemata und innovativer Bestrahlungskonzepte, die langfristige Prognose für den einzelnen Patienten verbessert werden. Ziel dieser Übersicht ist es, die aktuellen Konzepte für ausgewählte Tumore des Gastrointestinaltrakts vorzustellen und zu bewerten.

Abstract

Surgical therapy of any malignancy always attempts the complete removal of a cancer from the organism. An adjuvant chemotherapy has the goal to remove remaining tumor-cells, to prevent recurrence of the disease and to improve long term survival. Within the last years there has been a substantial improvement in prognosis due to multi-modal therapeutic regimens including combination-chemo-therapy and innovative radiation-protocols. This review aims to present and to critically review current concepts in the treatment of selected tumors of the gastrointestinal tract.

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  1. Klinik für Innere Medizin I, Zentrum für Innere Medizin, Universität Ulm, Robert-Koch-Straße 8, 89081, Ulm, Deutschland

    G. von Wichert &  T. Seufferlein

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  1. G. von Wichert
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  2. T. Seufferlein
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Correspondence to T. Seufferlein.

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von Wichert, G., Seufferlein, T. Adjuvante Chemotherapie bei soliden Tumoren des Gastrointestinaltrakts. Internist 48, 1335–1342 (2007). https://doi.org/10.1007/s00108-007-1974-y

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  • DOI: https://doi.org/10.1007/s00108-007-1974-y

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