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Medikamentöse Therapie der Komplikationen der Leberzirrhose

Medical therapy of complications in liver cirrhosis

  • Schwerpunkt: Was ist gesichert in der Therapie?
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Zusammenfassung

Patienten mit einer Leberzirrhose tragen das Risiko für eine Vielzahl von Komplikationen, die deutlich machen, dass es sich hierbei um eine Systemerkrankung handelt. Die medikamentösen Therapiemöglichkeiten der Komplikationen sind dementsprechend vielfältig. Sie reichen von akuten therapeutischen Maßnahmen wie der Gabe von vasoaktiven Substanzen im Rahmen einer akuten Varizenblutung bis zur Dauerprophylaxe mit oralen Antibiotika nach einer spontan bakteriellen Peritonitis. Dabei sollten allerdings die ursächliche Bekämpfung der Grunderkrankung, die Identifikation von Auslösern für akute Komplikationen und auch die Möglichkeit der Lebertransplantation immer im Auge behalten werden.

Abstract

Patients with liver cirrhosis bear a considerable risk of a variety of complications that involve virtually all organ systems. They can be addressed with a wide spectrum of drugs for acute interventions as well as for prophylactic purposes. At the same time treatment of the underlying disease, the identification and treatment of triggering factors and the possibility of liver transplantation should be kept in mind.

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Authors and Affiliations

  1. Medizinische Klinik und Poliklinik I, Universitätsklinikum, Rheinische Friedrich-Wilhelms-Universität, Sigmund-Freud-Straße 25, 53105, Bonn, Deutschland

    F. Grünhage, J. Heller, B. Appenrodt, V. Schmitz &  T. Sauerbruch

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  1. F. Grünhage
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  2. J. Heller
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  3. B. Appenrodt
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  4. V. Schmitz
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  5. T. Sauerbruch
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Correspondence to T. Sauerbruch.

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Grünhage, F., Heller, J., Appenrodt, B. et al. Medikamentöse Therapie der Komplikationen der Leberzirrhose. Internist 48, 1349–1357 (2007). https://doi.org/10.1007/s00108-007-1965-z

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  • DOI: https://doi.org/10.1007/s00108-007-1965-z

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