Zusammenfassung
In Deutschland werden pro Jahr etwa 100.000 herzchirurgische Operationen durchgeführt. Die häufigsten prognosebestimmenden postoperativen Probleme dieser Patienten bestehen in akuter Herzinsuffizienz, akuter Niereninsuffizienz, lokalen und systemischen Infektionen, neurologischen Komplikationen, Postkardiotomiesyndrom, Perikardtamponade und Vorhofflimmern. Eine gute Risikostratifizierung kardiochirurgischer Patienten kann anhand eines Scores erfolgen. Für den weiteren klinischen Verlauf dieser Patienten ist die Offenheitsrate der Bypässe entscheidend. Eine besondere Herausforderung für die moderne Kardiochirurgie stellt die Behandlung geriatrischer Patienten dar, wobei die Zahl von Herzoperationen bei Patienten in dieser Altersklasse zunimmt.
Abstract
In Germany, approximately 100,000 patients underwent cardiac surgery in 2005. The most important postoperative problems with prognostic impact for these patients were acute heart failure, acute renal failure, infections, neurological complications, postcardiotomy syndrome, cardiac tamponade and atrial fibrillation. The “EuroSCORE” is a relevant predictor of immediate and long-term outcome in these patients. The patency rates of coronary artery bypass grafts (CABG) are important for the long-term outcome in such surgery. There has been a significant increase in the number of patients aged 80 years and older who are referred for cardiac surgery, which is an outstanding challenge for cardiac surgeons.
Literatur
Alexander KP, Anstrom KJ, Muhlbaier LH et al. (2000) Outcomes of cardiac surgery in patients >or = 80 years: results from the National Cardiovascular Network. J Am Coll Cardiol 35: 731–738
Baim DS, Wahr D, George B et al. (2002) Randomized trial of a distal embolic protection device during percutaneous intervention of saphenous vein aorto-coronary bypass grafts. Circulation 105: 1285–1290
Bergman P, Linden J van der (2005) Atherosclerosis of the ascending aorta as a major determinant of the outcome of cardiac surgery. Nat Clin Pract Cardiovasc Med 2: 246–251; quiz 269
Biancari F, Kangasniemi OP, Luukkonen J et al. (2006) EuroSCORE predicts immediate and late outcome after coronary artery bypass surgery. Ann Thorac Surg 82: 57–61
Burgess DC, Kilborn MJ, Keech AC (2006) Interventions for prevention of post-operative atrial fibrillation and its complications after cardiac surgery: a meta-analysis. Eur Heart J 27: 2846–2857
Chiappini B, Camurri N, Loforte A et al. (2004) Outcome after aortic valve replacement in octogenarians. Ann Thorac Surg 78: 85–89
Cho KR, Kim JS, Choi JS et al. (2006) Serial angiographic follow-up of grafts one year and five years after coronary artery bypass surgery. Eur J Cardiothorac Surg 29: 511–516
Collart F, Feier H, Kerbaul F et al. (2005) Valvular surgery in octogenarians: operative risks factors, evaluation of Euroscore and long term results. Eur J Cardiothorac Surg 27: 276–280
Croal BL, Hillis GS, Gibson PH et al. (2006) Relationship between postoperative cardiac troponin I levels and outcome of cardiac surgery. Circulation 114: 1468–1475
Devbhandari MP, Duncan AJ, Grayson AD et al. (2006) Effect of risk-adjusted, non-dialysis-dependent renal dysfunction on mortality and morbidity following coronary artery bypass surgery: a multi-centre study. Eur J Cardiothorac Surg 29: 964–970
Finkelstein Y, Shemesh J, Mahlab K et al. (2002) Colchicine for the prevention of postpericardiotomy syndrome. Herz 27: 791–794
FitzGibbon GM, Leach AJ, Kafka HP et al. (1991) Coronary bypass graft fate: long-term angiographic study. J Am Coll Cardiol 17: 1075–1080
Fuster V, Ryden LE, Cannom DS et al. (2006) ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation: full text: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 guidelines for the management of patients with atrial fibrillation) developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society. Europace 8: 651–745
Hannan EL, Wu C, Ryan TJ et al. (2003) Do hospitals and surgeons with higher coronary artery bypass graft surgery volumes still have lower risk-adjusted mortality rates? Circulation 108: 795–801
Immer FF, Durrer M, Muhlemann KS et al. (2005) Deep sternal wound infection after cardiac surgery: modality of treatment and outcome. Ann Thorac Surg 80: 957–961
Iung B, Cachier A, Baron G et al. (2005) Decision-making in elderly patients with severe aortic stenosis: why are so many denied surgery? Eur Heart J 26: 2714–2720
John R, Choudhri AF, Weinberg AD et al. (2000) Multicenter review of preoperative risk factors for stroke after coronary artery bypass grafting. Ann Thorac Surg 69: 30–35; discussion 35–36
Khot UN, Friedman DT, Pettersson G et al. (2004) Radial artery bypass grafts have an increased occurrence of angiographically severe stenosis and occlusion compared with left internal mammary arteries and saphenous vein grafts. Circulation 109: 2086–2091
Kolh P, Kerzmann A, Lahaye L et al. (2001) Cardiac surgery in octogenarians; peri-operative outcome and long-term results. Eur Heart J 22: 1235–1243
Ling LH, Oh JK, Schaff HV et al. (1999) Constrictive pericarditis in the modern era: evolving clinical spectrum and impact on outcome after pericardiectomy. Circulation 100: 1380–1386
Maganti MD, Rao V, Borger MA et al. (2005) Predictors of low cardiac output syndrome after isolated aortic valve surgery. Circulation 112: I448–I452
Mathew JP, Fontes ML, Tudor IC et al. (2004) A multicenter risk index for atrial fibrillation after cardiac surgery. JAMA 291: 1720–1729
Mehta RH, Grab JD, O’Brien SM et al. (2006) Bedside tool for predicting the risk of postoperative dialysis in patients undergoing cardiac surgery. Circulation 114: 2208–2216; quiz 2208
Mitchell LB, Exner DV, Wyse DG et al. (2005) Prophylactic oral amiodarone for the prevention of arrhythmias that begin early after revascularization, valve replacement, or repair: PAPABEAR: a randomized controlled trial. JAMA 294: 3093–3100
Nashef SA, Roques F, Michel P et al. (1999) European system for cardiac operative risk evaluation (EuroSCORE). Eur J Cardiothorac Surg 16: 9–13
Olbrecht VA, Barreiro CJ, Bonde PN et al. (2006) Clinical outcomes of noninfectious sternal dehiscence after median sternotomy. Ann Thorac Surg 82: 902–907
Patti G, Chello M, Candura D et al. (2006) Randomized trial of atorvastatin for reduction of postoperative atrial fibrillation in patients undergoing cardiac surgery: results of the ARMYDA-3 (Atorvastatin for Reduction of MYocardial Dysrhythmia After cardiac surgery) study. Circulation 114: 1455–1461
Prince SE, Cunha BA (1997) Postpericardiotomy syndrome. Heart Lung 26: 165–168
Provenchere S, Berroeta C, Reynaud C et al. (2006) Plasma brain natriuretic peptide and cardiac troponin I concentrations after adult cardiac surgery: association with postoperative cardiac dysfunction and 1-year mortality. Crit Care Med 34: 995–1000
Rao V, Ivanov J, Weisel RD et al. (1996) Predictors of low cardiac output syndrome after coronary artery bypass. J Thorac Cardiovasc Surg 112: 38–51
Roach GW, Kanchuger M, Mangano CM et al. (1996) Adverse cerebral outcomes after coronary bypass surgery. Multicenter Study of Perioperative Ischemia Research Group and the Ischemia Research and Education Foundation Investigators. N Engl J Med 335: 1857–1863
Roques F, Nashef SA, Michel P et al. (1999) Risk factors and outcome in European cardiac surgery: analysis of the EuroSCORE multinational database of 19030 patients. Eur J Cardiothorac Surg 15: 816–822; discussion 822–813
Tatoulis J, Buxton BF, Fuller JA (2004) Patencies of 2127 arterial to coronary conduits over 15 years. Ann Thorac Surg 77: 93–101
Toumpoulis IK, Anagnostopoulos CE (2005) Can EuroSCORE accurately predict long-term outcome after cardiac surgery? Nat Clin Pract Cardiovasc Med 2: 620–621
Toumpoulis IK, Anagnostopoulos CE, Derose JJ Jr et al. (2005) The impact of deep sternal wound infection on long-term survival after coronary artery bypass grafting. Chest 127: 464–471
Vermeersch P, Agostoni P, Verheye S et al. (2006) Randomized double-blind comparison of sirolimus-eluting stent versus bare-metal stent implantation in diseased saphenous vein grafts: six-month angiographic, intravascular ultrasound, and clinical follow-up of the RRISC Trial. J Am Coll Cardiol 48: 2423–2431
Zakeri R, Freemantle N, Barnett V et al. (2005) Relation between mild renal dysfunction and outcomes after coronary artery bypass grafting. Circulation 112: I270–I275
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Fischer, D., Drexler, H. Aortokoronare Bypass- und Herzklappenoperationen. Internist 48, 586–596 (2007). https://doi.org/10.1007/s00108-007-1831-z
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DOI: https://doi.org/10.1007/s00108-007-1831-z